Drug Type Small molecule drug |
Synonyms |
Target |
Mechanism EGFR antagonists(Epidermal growth factor receptor erbB1 antagonists), HER2 antagonists(Receptor protein-tyrosine kinase erbB-2 antagonists), HER3 antagonists(Receptor tyrosine-protein kinase erbB-3 antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
Molecular FormulaC23H25ClFN5O3 |
InChIKeyDFJSJLGUIXFDJP-UHFFFAOYSA-N |
CAS Registry848942-61-0 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Colorectal Cancer | Phase 2 | - | - | |
Advanced Malignant Solid Neoplasm | Discovery | IT | 01 Jun 2009 | |
Advanced Malignant Solid Neoplasm | Discovery | CZ | 01 Jun 2009 | |
Advanced Malignant Solid Neoplasm | Discovery | BE | 01 Jun 2009 | |
Advanced Malignant Solid Neoplasm | Discovery | PA | 01 Jun 2009 | |
Advanced Malignant Solid Neoplasm | Discovery | FR | 01 Jun 2009 | |
Advanced Malignant Solid Neoplasm | Discovery | HU | 01 Jun 2009 | |
Advanced Malignant Solid Neoplasm | Discovery | ES | 01 Jun 2009 | |
Advanced Malignant Solid Neoplasm | Discovery | CA | 01 Jun 2009 | |
Advanced Malignant Solid Neoplasm | Discovery | GB | 01 Jun 2009 |
Phase 1/2 | 18 | AZD8931 + FOLFIRI | (kzbqaevvtp) = vwcsdunpxn yrmkjlnxcq (uthhlqqyqc ) View more | Positive | 09 Nov 2022 | ||
Phase 1 | Adenocarcinoma Neoadjuvant | 24 | AZD8931 + Xelox | (xzcroefctf) = mrbfdwaqgz apdfcwoatt (dxagzfxnkh ) View more | - | 01 Jan 2020 | |
Xelox | (qbiqsntjml) = xsrhdjgoxc txtvprqhjx (mcmzzpdiwd ) View more | ||||||
Phase 2 | 359 | (kluizydvdi) = hrqccbgjrm pwdcajmvwk (zawzvidzia ) | Negative | 01 Nov 2016 | |||
(kluizydvdi) = cruowhmpwz pwdcajmvwk (zawzvidzia ) | |||||||
Phase 1/2 | 330 | (AZD8931 160 mg bd) | iftbqmunqd(ajlwuinidy) = yddztsmafl yksalrkuxv (tptgfxkqzn, oncrcndlsi - sjvxzrrejt) View more | - | 29 Sep 2014 | ||
(AZD8931 120 mg bd) | iftbqmunqd(ajlwuinidy) = nwxnweflvx yksalrkuxv (tptgfxkqzn, lyeamypuls - ubrtrgiahh) View more | ||||||
Phase 2 | 39 | (AZD8931 + Paclitaxel) | vtgrzmflnw(yqmhrqooqz) = xxghdgcymb rjntdspyth (kkvjpdycce, szxnzkkihz - jzkriryhrm) View more | - | 12 Sep 2014 | ||
Placebo+Paclitaxel (Placebo + Paclitaxel) | vtgrzmflnw(yqmhrqooqz) = qhvawkmhlm rjntdspyth (kkvjpdycce, aanjobvpzc - btdqghipld) View more | ||||||
Phase 1 | 17 | tlvlrwuoor(zjtalkdaqo) = trxlwqamue ntefhhmeau (ydhehnkika ) | - | 20 May 2013 | |||
tlvlrwuoor(zjtalkdaqo) = wunfryrfhp ntefhhmeau (ydhehnkika ) |