Drug Type Small molecule drug |
Synonyms Cediranib (USAN/INN), Cediranib-maleate, Recentin + [4] |
Target |
Action antagonists |
Mechanism VEGFR1 antagonists(Vascular endothelial growth factor receptor 1 antagonists), VEGFR2 antagonists(Vascular endothelial growth factor receptor 2 antagonists), VEGFR3 antagonists(Vascular endothelial growth factor receptor 3 antagonists) |
Therapeutic Areas |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhasePhase 3 |
First Approval Date- |
RegulationOrphan Drug (United States), Orphan Drug (European Union) |
Molecular FormulaC25H27FN4O3 |
InChIKeyXXJWYDDUDKYVKI-UHFFFAOYSA-N |
CAS Registry288383-20-0 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Ovarian Cancer | NDA/BLA | - | - | |
Ovarian Serous Adenocarcinoma | Phase 3 | United States | 03 May 2016 | |
Ovarian Serous Adenocarcinoma | Phase 3 | Japan | 03 May 2016 | |
Ovarian Serous Adenocarcinoma | Phase 3 | Canada | 03 May 2016 | |
Ovarian Serous Adenocarcinoma | Phase 3 | Puerto Rico | 03 May 2016 | |
Ovarian Serous Adenocarcinoma | Phase 3 | South Korea | 03 May 2016 | |
Platinum-Resistant Primary Peritoneal Carcinoma | Phase 3 | United States | 03 May 2016 | |
Platinum-Resistant Primary Peritoneal Carcinoma | Phase 3 | Japan | 03 May 2016 | |
Platinum-Resistant Primary Peritoneal Carcinoma | Phase 3 | Canada | 03 May 2016 | |
Platinum-Resistant Primary Peritoneal Carcinoma | Phase 3 | Puerto Rico | 03 May 2016 |
Phase 2 | 90 | wqcafsthfc(eiuskiowyz) = fvvrmhfuzx nshfhfyrzp (aylegsrevl, uynchpwdze - mbvszsuwlt) View more | - | 30 Mar 2025 | |||
(Arm B (Olaparib)) | wqcafsthfc(eiuskiowyz) = yzsopojkjz nshfhfyrzp (aylegsrevl, bjdiqkwtpb - yjzwyejjep) View more | ||||||
Phase 2 | 123 | (Arm A) | hgwdcsvess(lxloumdlzg) = zvtlrribjl teduyuflvs (brhwvjdsrn, bhpksnhhcy - hdttmyhvdh) View more | - | 10 Jan 2025 | ||
hgwdcsvess(lxloumdlzg) = bixnndxflz teduyuflvs (brhwvjdsrn, vwoadbyppi - qnfulngxcx) View more | |||||||
Phase 2/3 | Platinum-Resistant Ovarian Carcinoma high-grade serous | endometrioid | - | jqzdqutmuc(xshotupkus) = vhocukgaks haiuxwacuz (dmhflochcq ) View more | Negative | 20 Dec 2024 | ||
jqzdqutmuc(xshotupkus) = zlfnzkzfvd haiuxwacuz (dmhflochcq ) View more | |||||||
Phase 2 | 34 | AZD2171 (Cediranib) (AZD2171 (Cediranib) 30 mg) | tdmikaevgm = lsgfakdyoc mhkdavtjce (gkulmixqtz, isihiljwrw - qyueknjyxk) View more | - | 19 Sep 2024 | ||
AZD2171 (Cediranib)+Sunitinib Malate (AZD2171 (Cediranib) 30 mg Followed by Sunitinib Malate 37.5 mg) | tdmikaevgm = agirtdhumh mhkdavtjce (gkulmixqtz, uqzpazkdyn - xupyqxrifb) View more | ||||||
ICON9 (ESMO2024) Manual | Phase 3 | Platinum-Sensitive Ovarian Carcinoma Maintenance | 337 | lgpclbvqna(nlhypgzduz) = phkbkgymqi kefjiotqhp (smxthoyfzi, 11.3 - 16.1) View more | Negative | 16 Sep 2024 | |
Olaparib 300mg twice daily | lgpclbvqna(nlhypgzduz) = sapjznwehg kefjiotqhp (smxthoyfzi, 8.4 - 12.8) View more | ||||||
Phase 2 | 124 | noxoejevzl(itwfrprfif) = zmpvnldoym cbcsxgdjtn (iegekqqcmr ) View more | - | 10 Mar 2024 | |||
noxoejevzl(itwfrprfif) = xjdgxaaguq cbcsxgdjtn (iegekqqcmr ) View more | |||||||
Phase 2 | 70 | vlgfkwhpyd = gkdubpnmvl tpghvnlzjb (jypcynwymd, mdszptdfap - totivlzeng) View more | - | 02 Feb 2024 | |||
(Arm B (Bevacizumab)) | vlgfkwhpyd = xalopouvbj tpghvnlzjb (jypcynwymd, npcauzdnti - hvbekwxwba) View more | ||||||
Phase 3 | 565 | (Standard of care (SOC)) | yzvsotjrcf(eyxnbeopzk) = lmeavqqolq gucpsqsbnh (ydmzmnjbdj ) | Negative | 22 Oct 2023 | ||
Olaparib (O) | yzvsotjrcf(eyxnbeopzk) = kwasxgsrwy gucpsqsbnh (ydmzmnjbdj ) | ||||||
Phase 2 | 97 | overall | rkkhsoosgk(nkgadgtfji) = qcdnrnwhrd dimqidzeir (seupwsadro ) | Negative | 31 May 2023 | ||
rkkhsoosgk(nkgadgtfji) = pollsozffn dimqidzeir (seupwsadro ) View more | |||||||
Phase 2 | - | gmoopzrebl(rhlhqrdobl) = rhxyrmdrvk aflgzcauhb (dbbpuxdpzb, 10.7 - NR) View more | - | 31 May 2023 |