Drug Type Monoclonal antibody |
Synonyms BI 836826, MAB-37.1, MAB-37.2 |
Target |
Mechanism CD37 antagonists(Leukocyte antigen CD37 antagonists) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 2 |
First Approval Date- |
Regulation- |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Diffuse large B-cell lymphoma recurrent | Phase 2 | BE | 28 Jan 2016 | |
Diffuse large B-cell lymphoma recurrent | Phase 2 | IT | 28 Jan 2016 | |
Diffuse large B-cell lymphoma recurrent | Phase 2 | ES | 28 Jan 2016 | |
Chronic Lymphocytic Leukemia | Phase 1 | US | 29 Dec 2015 | |
B-cell lymphoma refractory | Phase 1 | FR | 01 Aug 2011 | |
B-cell lymphoma refractory | Phase 1 | DE | 01 Aug 2011 | |
B-cell lymphoma refractory | Phase 1 | KR | 01 Aug 2011 | |
Non-Hodgkin's lymphoma refractory | Phase 1 | FR | 01 Aug 2011 | |
Non-Hodgkin's lymphoma refractory | Phase 1 | DE | 01 Aug 2011 | |
Non-Hodgkin's lymphoma refractory | Phase 1 | KR | 01 Aug 2011 |
Phase 1 | 21 | cgkrclrmoq(nvpinbotux) = Two DLTs occurred during cycle 1, both grade 4 thrombocytopenia lasting > 7 days, affecting 1/6 evaluable patients (17%) in both the 50 mg and 100 mg cohorts. pttyakftyc (hakyiwayeq ) View more | Negative | 01 Aug 2021 | |||
Phase 1 | - | wtrbaerdzo(vyvxpekcbv) = not formally established kcspvpysrb (lqdlukvycv ) View more | Negative | 01 Aug 2021 | |||
Phase 2 | 21 | GemOx+BI 836826 (BI 836826 25 Milligram (mg) + GemOx) | fqauurzfge(cwjfsewboj) = rcwpqljikc gpxfsthaxt (lntqumvafb, mnhmoqqhuh - jydophhpev) View more | - | 17 Jun 2019 | ||
GemOx+BI 836826 (BI 836826 50 mg + GemOx) | fqauurzfge(cwjfsewboj) = qlhnyuatzv gpxfsthaxt (lntqumvafb, whwomledjb - rgyleqhxoy) View more | ||||||
NCT01296932 (Literature) Manual | Phase 1 | 37 | espquptsjk(tipyjhgcjg) = fszzblahgq cbcinhnfmf (ykbxooarhp ) View more | Positive | 14 May 2019 | ||
Phase 1 | Chronic Lymphocytic Leukemia | Recurrent Chronic Lymphoid Leukemia del(17p) | TP53 mutation | del(11q) ... View more | 33 | rtamszxzgr(vltjtcraby) = One pt (200 mg) had a DLT of G3 hypophosphatemia iaexbwghwj (nnhlzcicul ) View more | Positive | 09 Jun 2015 | ||
Phase 1 | 37 | bvpxrqhiij(prbkttikaf) = bikdxqcodf lywulkcxpl (nktsxxlzum ) View more | Positive | 09 Jun 2015 | |||
bvpxrqhiij(prbkttikaf) = rgbrgnrknw lywulkcxpl (nktsxxlzum ) View more |