Last update 21 Dec 2024

Calcium Dobesilate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Calcium dobesilate (INN), Calcium Dobesilate Capsules, Calcium Dobesilate Granules
+ [9]
Target
Mechanism
VEGFR2 antagonists(Vascular endothelial growth factor receptor 2 antagonists)
Inactive Indication-
Originator Organization-
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure

Molecular FormulaC12H12CaO10S2
InChIKeyAEWLOKQYGXDGFV-UHFFFAOYSA-N
CAS Registry20123-80-2

External Link

R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Arteriosclerosis Obliterans
CN
04 Jul 1992
Chronic venous insufficiency
CN
04 Jul 1992
Hypertension
CN
04 Jul 1992
Microvascular Disease
CN
04 Jul 1992
Phlebitis
CN
04 Jul 1992
Spasm
CN
04 Jul 1992
Ulcer
CN
04 Jul 1992
Varicose Veins
CN
04 Jul 1992
Diabetic Retinopathy
KR
19 Jan 1988
Edema
KR
19 Jan 1988
Hemorrhoids
KR
19 Jan 1988
Postthrombotic Syndrome
KR
19 Jan 1988
Venous Insufficiency
KR
19 Jan 1988
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetic NephropathiesPreclinical-23 Oct 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
uqebirtlwp(ukbsnqeobf) = doqxricurf cmudvjslza (ubmdzbfivt )
-
01 Apr 2009
Not Applicable
Diabetic Retinopathy
type 2 diabetes
194
Doxium® (DX) 2g
qtndtjpjss(sgwjyyfizh): P-Value = 0.0016
Positive
01 May 2004
Placebo
Not Applicable
194
gkbywiqxue(whnlokvrzp): P-Value = p0.044
-
01 May 2004
Placebo
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Approval

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Regulation

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