Shenyang Huatai Medication Research Co., Ltd.

Main purpose: To compare agomelatine tablets (25mg) provided by Shenyang Funing Pharmaceutical Co., Ltd. and agomelatine tablets (25mg, brand name: Differences in the degree and rate of absorption of Dimension New®) in healthy adult populations to evaluate its bioequivalence. Secondary purpose: To evaluate the efficacy of agomelatine tablets (25 mg) provided by Shenyang Funing Pharmaceutical Co., Ltd. and agomelatine tablets (25 mg, trade name) licensed by Les Laboratoires Servier under fasting and postprandial administration conditions. : Dimension New®) safety in healthy adults.

This trial was designed to study the pharmacokinetic characteristics of escitalopram oxalate tablets (10 mg) administered by healthy subjects on an empty stomach and after a meal, developed by Shenyang Huatai Pharmaceutical Research Co., Ltd. and produced by Shenyang Funing Pharmaceutical Co., Ltd. ; Using Escitalopram Oxalate Tablets (Lexopram®, 10 mg) produced by H. Lundbeck A/S as a reference preparation, compare the pharmacokinetic parameters of the two preparations and evaluate the human bioequivalence of the two preparations , and observe the safety of the two preparations in healthy subjects.

main purpose Comparing postprandial administration conditions, the trazodone hydrochloride tablets (50 mg) provided by Shenyang Funing Pharmaceutical Co., Ltd. and the trazodone hydrochloride tablets (50 mg, trade name: RESLIN®) licensed by Erygonic Co., Ltd. are effective in healthy adults. The difference in absorption degree and speed was evaluated to evaluate its bioequivalence. secondary purpose To evaluate the effects of trazodone hydrochloride tablets (50 mg) provided by Shenyang Funing Pharmaceutical Co., Ltd. and trazodone hydrochloride tablets (50 mg, trade name: RESLIN®) certified by Erygonic Co., Ltd. in healthy adults under postprandial administration conditions. security in.