Bozhiyan New Taizhou Pharmaceutical Technology Co., Ltd.

Main purpose To study the pharmacokinetics of a single oral dose of the test preparation of sildenafil citrate orodispersible film (specification: 50 mg) and the reference preparation of sildenafil citrate orodispersible film (trade name: Viagra®, specification: 50 mg) in healthy male subjects in China under fasting and fed conditions, and to evaluate the bioequivalence of the two preparations when taken orally under fasting and fed conditions. Secondary purpose 1. To observe the safety of the test preparation of sildenafil citrate orodispersible film and the reference preparation in healthy male subjects. 2. To evaluate the taste (palatability), oral dissolution time, mucosal adhesion and irritation of the test preparation of sildenafil citrate orodispersible film and the reference preparation.

Primary objective: To study the pharmacokinetic characteristics of the test preparation avatrombopag maleate tablets (specification: 20 mg) and the reference preparation avatrombopag maleate tablets (Doptelet/Su Kexin, specification: 20 mg) in healthy adult subjects, and to evaluate the oral bioequivalence of the two preparations. Secondary objective: To study the safety of the test preparation avatrombopag maleate tablets (specification: 20 mg) and the reference preparation avatrombopag maleate tablets (Doptelet/Su Kexin) (specification: 20 mg) in healthy subjects.