Lepu Pharmaceuticals Co., Ltd.

Primary objective: To compare the similarity of the pharmacokinetic characteristics of LPS-001 injection and Novota® after a single dose in healthy Chinese subjects, using LPS-001 injection developed by Lepu Pharmaceutical Co., Ltd. as the test drug and semaglutide injection (Novota®) produced by Novo Nordisk A/S as the reference drug. Secondary objective: To compare the safety of LPS-001 injection and Novota® in healthy Chinese adult subjects.

(1) To evaluate the safety and tolerability of multiple-use atropine sulfate eye drops in healthy adult subjects; (2) To evaluate the pharmacokinetic characteristics of multiple-use atropine sulfate eye drops in healthy adult subjects.

Primary purpose: To study the absorption rate and extent of sildenafil citrate tablets (specification: 100 mg) developed by Lepu Pharmaceutical Co., Ltd., using sildenafil citrate tablets (trade name: Viagra®; specification: 100 mg) held by Pfizer Pharmaceuticals Co., Ltd. as the reference preparation in healthy subjects under fasting or postprandial conditions, and to evaluate whether the test preparation and the reference preparation are bioequivalent. Secondary purpose: To observe the safety of oral test preparations and reference preparations in healthy subjects.