[Translation] A Phase I, randomized, double-blind, placebo-controlled study to evaluate the safety, tolerability, and pharmacokinetic characteristics of Troriluzole (BHV-4157) 280 mg after single and multiple doses in healthy Chinese subjects
主要目的:评估在中国健康受试者中单次(280 mg)和多次(280 mg/日,连续5天)给药Troriluzole后的安全性和耐受性。
次要目的:评估在中国健康受试者中单次(280 mg)和多次(280 mg/日,连续5天) 给药Troriluzole后利鲁唑的药代动力学(PK)特征。
[Translation] Primary objective: To evaluate the safety and tolerability of troriluzole after single (280 mg) and multiple (280 mg/day, 5 consecutive days) administration in healthy Chinese subjects.
Secondary objective: To evaluate the pharmacokinetic (PK) characteristics of riluzole after single (280 mg) and multiple (280 mg/day, 5 consecutive days) administration of troriluzole in healthy Chinese subjects.