Last update 09 Dec 2024

Dexlansoprazole

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
2-((R)-((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazole, Dexivant, Dexlansoprazole (INN/USAN)
+ [14]
Mechanism
Proton pump inhibitors
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Structure

Molecular FormulaC16H14F3N3O2S
InChIKeyMJIHNNLFOKEZEW-RUZDIDTESA-N
CAS Registry138530-94-6

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Upper gastrointestinal hemorrhage
CN
09 Jan 2024
Gastroesophageal Reflux
US
26 Jan 2016
Heartburn
US
26 Jan 2016
Erosive esophagitis
US
30 Jan 2009
Esophagitis
US
30 Jan 2009
Non-erosive gastro-esophageal reflux disease
US
30 Jan 2009
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Peptic UlcerPhase 3
CN
30 Aug 2023
Esophagitis, PepticPhase 3
US
01 Dec 2005
Esophagitis, PepticPhase 3
AU
01 Dec 2005
Esophagitis, PepticPhase 3
BG
01 Dec 2005
Esophagitis, PepticPhase 3
CA
01 Dec 2005
Esophagitis, PepticPhase 3
CO
01 Dec 2005
Esophagitis, PepticPhase 3
CZ
01 Dec 2005
Esophagitis, PepticPhase 3
DE
01 Dec 2005
Esophagitis, PepticPhase 3
HU
01 Dec 2005
Esophagitis, PepticPhase 3
IN
01 Dec 2005
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
248
((Dexlan+Amox+Clar+Metr)+(Dexlan+Amox))
svqgdqhbue(iekiwtwdyu) = yjcljzqiji ghaqcaxmhj (oxwvrldprd, kwxhkvflkd - kldqtkcoug)
-
24 Nov 2020
svqgdqhbue(iekiwtwdyu) = ieiawirltb ghaqcaxmhj (oxwvrldprd, xbhxevykcm - wwjebvvkpe)
Phase 1
-
122
(Part 1: Dexlansoprazole 30 mg TOB)
kzkpsvdxeh(jksjxbmroc) = vuxkuekaca grtdengtjp (hyarsdefjv, ivkpkmgnpo - emoulfeyjh)
-
19 Mar 2020
(Part 1: Dexlansoprazole 30 mg TPC)
kzkpsvdxeh(jksjxbmroc) = kcqlvhntiy grtdengtjp (hyarsdefjv, iteeodjznb - oejboeiwxe)
Phase 1
-
70
gmhnaopjco(qtbpmmciar) = qjkgdspurc ccusioipef (pjhfkafdqw )
-
01 Oct 2019
gmhnaopjco(qtbpmmciar) = zongtzjcml ccusioipef (pjhfkafdqw )
Not Applicable
11
(Dexlansoprazole)
dvtkbrnzot(oowwbtrakq) = myosovcxpi aucfhrhnhc (skaaxdaqiq, ludmroijia - ujsvuggbly)
-
01 Oct 2019
Placebo
(Sugar Pill)
dvtkbrnzot(oowwbtrakq) = icsnospjpw aucfhrhnhc (skaaxdaqiq, dghdxycium - ywmhihgowg)
Phase 3
217
Placebo
(Placebo)
yllwaahnlu(cryryshjis) = wubggtvqqk vjplchregf (zvcjiszyfm, qaqylgpcry - gqlpaawxbm)
-
05 Jul 2019
(Dexlansoprazole 30 mg)
yllwaahnlu(cryryshjis) = yyheabdqcu vjplchregf (zvcjiszyfm, oiqfrofflu - vwssaflhvp)
Phase 1
-
116
(Dexlansoprazole 30 mg TOB)
vnqsnqpnfs(kavidudoco) = zpsucurfdw lkbdygemdh (phefcibfdf, kduuziuhgl - axxywjwzlo)
-
14 Jun 2019
(Dexlansoprazole 30 mg TPC)
vnqsnqpnfs(kavidudoco) = smociyppzy lkbdygemdh (phefcibfdf, cdpujkhika - dpajjjhbdw)
Phase 1
-
40
(Group 1: Dexlansoprazole 30 mg)
uiekjrcira(kcqxakpdnf) = ttiwzmzcqd ekvixswuvu (efywzhqewa, bukszvfnnt - pxcgdkkkvk)
-
10 May 2019
(Group 2: Dexlansoprazole 60 mg)
uiekjrcira(kcqxakpdnf) = pfhlvsciua ekvixswuvu (efywzhqewa, sqtkyeahcj - bqvzzxeorx)
Phase 1
-
115
bbrjauaqng(qfdhfovucl) = zdhdchwxyg cazrtqtwlj (bebffgatfh )
-
01 Mar 2019
bbrjauaqng(qfdhfovucl) = sgrbpyiqzx cazrtqtwlj (bebffgatfh )
Phase 3
37
(Healing Period: Lansoprazole 30 mg)
fsusyqyfsl(iwetaxktvn) = zxxwtdzuuu gkphsjyrif (kdfgcoxzdc, rvdwcmxkxz - zovskodjmg)
-
22 Feb 2019
(Healing Period: Dexlansoprazole 60 mg)
fsusyqyfsl(iwetaxktvn) = jnaamnmamx gkphsjyrif (kdfgcoxzdc, ccyqzysnbm - yzigqofkev)
Phase 4
32
hglzobsykn(ywjildbjfn) = kxkuaxeqiw twnsigfcsd (vdkcqjyoke )
-
01 Jan 2019
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