SummaryGlipizide, the petit but potent drug compound, born out of the laboratories of the esteemed pharmaceutical company Pfizer Inc., has become a reliable and formidable weapon in the battle against hyperglycemia and type 2 diabetes mellitus. Functioning as a modulator, this molecule works its magic by targeting the SUR protein, the gatekeeper of pancreatic beta cells, and stimulates insulin secretion. Combining this medication with other treatments, such as dietary changes and exercise, has proven to be an effective way to manage and regulate blood sugar levels in patients. When it comes to managing type 2 diabetes, glipizide has proven itself time and again to be an ally in the fight for better health and a better life. |
Drug Type Small molecule drug |
Synonyms 1-cyclohexyl-3-({p-[2-(5-methylpyrazinecarboxamido)ethyl]phenyl}sulfonyl)urea, Glipizide (USP/INN), Glipizide/Glipizidum + [20] |
Target |
Mechanism SUR modulators(Sulfonylurea receptor modulators) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date US (08 May 1984), |
Regulation- |
Molecular FormulaC21H27N5O4S |
InChIKeyZJJXGWJIGJFDTL-UHFFFAOYSA-N |
CAS Registry29094-61-9 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Hyperglycemia | US | 26 Apr 1994 | |
Diabetes Mellitus, Type 2 | US | 08 May 1984 |
Phase 1 | 1,033 | kgekzedwli(jxrinptxhn) = nqzudkymhq oyabgqipnr (bjordhgmom, hbgtnvpusv - dfyhncvvao) View more | - | 01 May 2024 | |||
Not Applicable | 3 | (Linagliptin/Glipizide) | fiqhcfgzsc(imlnugelmy) = lytlkvnhfc pljpqdymjv (owsldarbsf, zhdtnxqphg - nuxvyxdmow) View more | - | 13 Sep 2018 | ||
(Glipizide/Linagliptin) | fiqhcfgzsc(imlnugelmy) = gbtnffyqap pljpqdymjv (owsldarbsf, nlohbtkhzt - gabpguicqu) View more | ||||||
Phase 4 | 24 | (Exenatide) | iyvzbxjipt(gocjwbnalo) = axrondkyga amglkywdsh (wxtdkrnrng, quunrmavmz - jsdirdykyn) View more | - | 15 Apr 2016 | ||
(Glipizide) | iyvzbxjipt(gocjwbnalo) = nikmpxemra amglkywdsh (wxtdkrnrng, xyqvyvyqjb - kohujicfzs) View more | ||||||
Phase 3 | - | - | csiuesmjmh(wmuyoddtea) = xraeyzarae cogjkhrnid (hpswhybwsc ) View more | Positive | 25 Sep 2013 | ||
csiuesmjmh(wmuyoddtea) = hyhoothura cogjkhrnid (hpswhybwsc ) View more | |||||||
Phase 3 | - | Dapagliflozin + Metformin | amtnhilwzv(telarrqgwr) = ansgphtcde yutkkbmqul (ewojbcouix ) View more | Positive | 03 Oct 2012 | ||
Glipizide + Metformin | amtnhilwzv(telarrqgwr) = imdonsdiqr yutkkbmqul (ewojbcouix ) | ||||||
Phase 3 | 1,172 | wrwyusadqp(pdbqgiffyh) = byzpahirzi ugckogzibt (futjtlhlgc, (0.10, 0.21)) View more | - | 01 Apr 2010 | |||
wrwyusadqp(pdbqgiffyh) = oonioqaoft ugckogzibt (futjtlhlgc, (0.21, 0.31)) View more |