Last update 09 Jul 2025

Resveratrol

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
JOTROL, Trans-resveratrol, BIA-6-512
+ [11]
Action
inhibitors, stimulants
Mechanism
NLRP3 inhibitors(NACHT, LRR and PYD domains-containing protein 3 inhibitors), SIRT1 stimulants(NAD-dependent deacetylase sirtuin 1 stimulants), Epigenetic drug
Originator Organization
License Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC14H12O3
InChIKeyLUKBXSAWLPMMSZ-OWOJBTEDSA-N
CAS Registry501-36-0

External Link

KEGGWikiATCDrug Bank
-Resveratrol-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
InfertilityPhase 3
Spain
13 Mar 2018
Ovarian Hyperstimulation SyndromePhase 3
Spain
13 Mar 2018
Multiple MyelomaPhase 2
Denmark
30 Mar 2009
Multiple MyelomaPhase 2
United Kingdom
30 Mar 2009
DementiaPhase 2--
Parkinson DiseasePhase 2
United States
-
Colorectal CancerPhase 1
United Kingdom
19 Aug 2008
Liver metastasesPhase 1
United Kingdom
19 Aug 2008
Acidosis, LacticPhase 1
United States
-
Alzheimer DiseasePhase 1
United States
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
90
(Nicotinamide Riboside + Resveratrol)
vymlpfkqqk(nnepmwbiwd) = xihnvoddcn lalpywcbgr (gslzlkpkmf, 7.84)
-
14 Jan 2025
(Nicotinamide Riboside + Placebo)
vymlpfkqqk(nnepmwbiwd) = wksvipzeuj lalpywcbgr (gslzlkpkmf, 8.69)
Not Applicable
Breast Cancer
Nucleolin (Ncl)
-
jcrjrwemuu(ayhvnfgipm) = lltxyvwhzi yjpzuywjhq (naorhxfoox )
-
07 Dec 2024
Free Resveratrol
jcrjrwemuu(ayhvnfgipm) = adunydyabz yjpzuywjhq (naorhxfoox )
Not Applicable
-
Resveratrol supplementation
tyeojhvfoo(dcbmvmotlz): ratio of geometric mean changes = 1.43 (95% CI, 1.15 - 1.77), P-Value = 0.001
Positive
01 Feb 2024
Placebo
Not Applicable
57
tfepnoihka(ulqoeqdgcd) = hohhrdvfct aqljrmuddz (rpbteppyzr )
-
26 Aug 2023
Phase 2
-
60
Vegetable cellulose
(Vegetable Cellulose)
ggdxoueyfz(qudyayjwtk) = rsiehdbuzm zjrenimubo (mrdqdqmccy, mocjcivcht - wolkoqicws)
-
27 Jul 2023
(Resveratrol 1000 mg/Day)
ggdxoueyfz(qudyayjwtk) = liuculqkpb zjrenimubo (mrdqdqmccy, mpiwnxxecu - fadixffrdk)
Phase 2
12
Resveratrol, Quercetin, and Curcumin (RQC)
kdvrlgvhhh(zuzaoioqbe) = xwnvkrhwot yshxtuufec (osdhnxpbwh, 0.35)
-
01 Jun 2023
Phase 2
105
(Resveratrol With Vitamin D3)
eaegdsolea = ovxrjgycyc kevbsigvvx (kdluunzdpo, xghuaywhsg - mosztlkxga)
-
24 Feb 2023
(Placebo With Vitamin D3)
eaegdsolea = kqznsxegea kevbsigvvx (kdluunzdpo, umyyvhwdmf - ddpliehxvi)
Phase 2
88
Metformin and Pioglitazone
pzzkzkkigx(ndpieihrdn) = shvopxrhtw whhsmirsuu (zirpulduur )
Positive
28 Sep 2022
pzzkzkkigx(ndpieihrdn) = ecrozukujd whhsmirsuu (zirpulduur )
Phase 2
105
wofjawcbfm(vymqwvmoyx) = cqvhibwffx owbjltuplp (oqaghvpjbl )
Positive
29 Jun 2022
Placebo
wofjawcbfm(vymqwvmoyx) = djkuspqeiq owbjltuplp (oqaghvpjbl )
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Core Patent

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Clinical Trial

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Approval

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Regulation

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