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Last update 22 Sep 2026

Clobazam

Last update 22 Sep 2026

Overview

R&D Status

Clinical Result

Translational Medicine

Overview

Basic Info

Drug Type

Small molecule drug

Synonyms

1-phenyl-5-methyl-8-chloro-1,2,4,5-tetrahydro-2,4-dioxo-3H-1,5-benzodiazepine, 7-Chloro-1-methyl-5-phenyl-1,5-dihydro-benzo[b][1,4]diazepine-2,4-dione, CLB

+ [18]

Target

GABAA receptor

Action

agonists

Mechanism

GABAA receptor agonists(Gamma-aminobutyric acid A receptor agonists)

Therapeutic Areas

Nervous System DiseasesCongenital DisordersOther Diseases

Active Indication

Lennox Gastaut SyndromeSeizuresAnxiety Disorders+ [1]

Inactive Indication

Epilepsia Partialis ContinuaEpilepsies, MyoclonicEpilepsy, Generalized

Originator Organization

Sanofi-Aventis Australia Pty Ltd.

Active Organization

Sumitomo Pharma Co., Ltd.Lundbeck Pharmaceuticals Ltd.

Cosette Pharmaceuticals, Inc.

+ [3]

Inactive Organization

Lundbeck LLC

H. Lundbeck A/S

License Organization

Aquestive Therapeutics, Inc.

Sanofi-Aventis U.S. LLC

Assertio Holdings, Inc.

+ [3]

Drug Highest PhaseApproved

First Approval Date

Australia (01 Aug 1991),

Anxiety DisordersEpilepsy

RegulationOrphan Drug (United States), Priority Review (China)

Structure/Sequence

Molecular FormulaC16H13ClN2O2

InChIKeyCXOXHMZGEKVPMT-UHFFFAOYSA-N

CAS Registry22316-47-8

Clinical Trials associated with Clobazam

CTR20254346

/ CompletedNot Applicable

氯巴占口服混悬液人体生物等效性试验（预试验）

[Translation] Human bioequivalence study (preliminary study) of clonazirium oral suspension.

主要研究目的：研究健康研究参与者在空腹状态下单次口服受试制剂氯巴占口服混悬液【规格：2.5mg/ml（120ml:300mg），宜昌人福药业有限责任公司生产】与参比制剂氯巴占口服混悬液【商品名：ONFI，规格：2.5mg/ml（120ml:300mg）；持证商：Lundbeck Pharmaceuticals LLC】的药代动力学，评价空腹状态口服两制剂的生物等效性。次要研究目的：研究受试制剂氯巴占口服混悬液2.5mg/ml（120ml:300mg）和参比制剂氯巴占口服混悬液（商品名：ONFI）2.5mg/ml（120ml:300mg）在健康研究参与者中的安全性。

[Translation]

Primary Objective: To investigate the pharmacokinetics of a single oral dose of the test formulation clobazian oral suspension (2.5 mg/ml (120 ml:300 mg), manufactured by Yichang Renfu Pharmaceutical Co., Ltd.) and the reference formulation clobazian oral suspension (trade name: ONFI, 2.5 mg/ml (120 ml:300 mg); licensee: Lundbeck Pharmaceuticals LLC) in healthy study participants under fasting conditions, and to evaluate the bioequivalence of the two formulations under fasting conditions. Secondary Objective: To investigate the safety of the test formulation clobazian oral suspension 2.5 mg/ml (120 ml:300 mg) and the reference formulation clobazian oral suspension (trade name: ONFI) 2.5 mg/ml (120 ml:300 mg) in healthy study participants.

Start Date05 Nov 2025

Sponsor / Collaborator

Yichang Humanwell Pharmaceuticals Co., Ltd.

IRCT20220211053992N49

/ SuspendedNot ApplicableIIT

In vivo fasted-state bioequivalence study of Clobazam 250 mg/ml suspension manufactured by Ashbal shimi Pharmaceutical Co. compared to innovator product

Start Date01 Aug 2025

Sponsor / Collaborator

Tabriz University of Medical Sciences

CTR20243975

/ CompletedPhase 4

Frisium和依诺思治疗Lennox-Gastaut综合征的多中心、随机、交叉、对照临床试验

[Translation] A multicenter, randomized, crossover, controlled clinical trial of Frisium and Enox in the treatment of Lennox-Gastaut syndrome

主要目的：评估LGS患者使用Frisium（氯巴占片）和依诺思（氯巴占片）治疗癫痫发作的等效性；次要目的：评估LGS患者使用依诺思（氯巴占片）治疗癫痫发作的有效性和安全性。

[Translation]

Primary objective: To evaluate the equivalence of Frisium (clobazam tablets) and Enox (clobazam tablets) in treating epileptic seizures in patients with LGS; Secondary objective: To evaluate the efficacy and safety of Enox (clobazam tablets) in treating epileptic seizures in patients with LGS.

Start Date09 Jan 2025

Sponsor / Collaborator

Yichang Humanwell Pharmaceuticals Co., Ltd.

100 Clinical Results associated with Clobazam

100 Translational Medicine associated with Clobazam

100 Patents (Medical) associated with Clobazam

2,080

Literatures (Medical) associated with Clobazam

01 Nov 2026·JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Validation of qualitative and quantitative methods for 40 benzodiazepines and Z-drugs in hair by UPLC-MS/MS

Article

Author: Yan, Hui ; Zhao, Junbo ; Yu, Shujie ; Yan, Fang ; Zhang, Miao ; Xiang, Ping

In recent years, the analysis and identification of benzodiazepines and Z-drugs have presented significant challenges in forensic medicine and pharmaceutical analysis due to their widespread use. Notably, some of these substances are classified as new psychoactive substances (NPS) by the UNODC. Hair was chosen as a biological matrix for monitoring long-term drug intake in this study. We aimed to develop and validate a rapid and sensitive method for simultaneous determination of 40 benzodiazepines and Z-drugs in hair using ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). All the analytes were detected within 11 min. The method was validated with linear calibration curves over the range of 5-500 pg mg^-1 (coefficient of determination, r² > 0.99). The limits of detection (LOD) were 1-3 pg mg^-1, and the limits of quantification (LOQ) were 5 pg mg^-1. The method demonstrated acceptable selectivity, accuracy, and precision (< 20%). Matrix effects ranged from -29.8-23.5%, and recoveries ranged from 77.9% to 119.9%. The method was successfully applied to six authentic hair samples, detecting nine substances: Nitrazepam, Temazepam, Lorazepam, 7-Aminoflunitrazepam, Clobazam, Lormetazepam, α-Hydroxyalprazolam, 7-Aminoclonazepam, and Zolpidem. Benzodiazepines concentrations ranged from 5.6 to 436.1 pg mg^-1, while zolpidem concentrations ranged from 11.1 to 113.8 pg mg^-1. This method provided a reliable tool for detecting benzodiazepines and Z-drugs in hair and addresses the requirements of routine forensic practice.

01 Nov 2026·EPILEPSY & BEHAVIOR

Infertility treatment in women with epilepsy: A systematic review

Review

Author: Hergenrader, Alexandra ; Maisenbacher, Mathias ; Nofal, Yazan ; Sane, Caroline ; Jennings, Carly ; Alshaqi, Ola ; Schmidt, Cynthia ; Taraschenko, Olga

BACKGROUND:

The impact of assisted reproductive technologies (ART) on seizure control in women with epilepsy remains incompletely understood.

METHODS:

A systematic review was conducted according to PRISMA guidelines. EMBASE, MEDLINE, CINAHL, Scopus, and the Cochrane Library were searched from inception to March 2025. Eligible studies included observational studies and case-based reports involving women undergoing infertility treatment.

RESULTS:

A total of 1216 publications were identified, of which four studies met the inclusion criteria, including case reports, a case series, and a cohort study. These studies included 16 women aged 25-46 years undergoing infertility treatment, all but one of whom had epilepsy. Interventions involved in vitro fertilization (IVF), ovulation induction, and hormonal therapies. Patients were treated with a range of antiseizure medications (ASMs), including carbamazepine, clobazam, lamotrigine, levetiracetam, oxcarbazepine, valproate, and zonisamide, either as monotherapy or in combination. Seizure frequency was generally stable, with most patients maintaining baseline seizure control. Seizure exacerbations were uncommon and primarily associated with hormonal therapy and reduced ASM levels, particularly reduced lamotrigine levels. Reported events included breakthrough seizures in the setting of decreased lamotrigine concentrations, seizure clusters associated with follitropin beta, and a new-onset seizure following dehydroepiandrosterone exposure. Across studies, multiple ART attempts resulted in live births with different ASM regimens, as well as in patients not receiving ASMs.

CONCLUSION:

Available evidence suggests that ART is feasible in women with epilepsy, with most patients maintaining stable seizure control. Hormonal therapy may affect ASM pharmacokinetics and seizure threshold, thereby warranting close monitoring. Larger prospective studies are needed to better define ASM-specific effects and optimize care.

01 Aug 2026·EPILEPSY & BEHAVIOR

Impact of antiseizure medications on thyroid function in persons with epilepsy

Article

Author: Menon, Ramshekhar N ; Bhasi, Ankith ; Radhakrishnan, Ashalatha ; Koshy, Kiren G ; Ram, Nadarajan Aravind ; Rohith, Maraludevanapura Govindaiah ; Manisha, K Y ; Bharanidharan, Gurumurthy

BACKGROUND:

Antiseizure medications (ASMs) are central to epilepsy management but may disrupt endocrine function, particularly thyroid homeostasis. Subclinical and central hypothyroidism are increasingly recognized among ASM users, yet routine thyroid monitoring remains uncommon.

OBJECTIVE:

To evaluate the prevalence and patterns of thyroid dysfunction in epilepsy patients on ASMs and compare the impact of older versus newer ASMs on thyroid function.

METHODS:

This cross-sectional study included 203 patients with epilepsy admitted to a tertiary epilepsy care centre in South India between July 2013 and March 2014. Patients with known thyroid disorders or other conditions affecting thyroid function were excluded. Thyroid function tests (TSH, fT3, fT4) were performed. Subclinical hypothyroidism was defined as elevated TSH with normal fT3/fT4; central hypothyroidism as low fT3/fT4 with normal or low TSH. ASMs were categorized into older and newer groups. Data were analysed using SPSS with appropriate parametric and non-parametric methods.

RESULTS:

Subclinical hypothyroidism was found in 11.3% of patients, more common in generalized epilepsy (56.5%) than focal epilepsy (43.5%) (p = 0.005). Valproate and clonazepam were most frequently associated. Among patients on monotherapy, none on newer ASMs had subclinical hypothyroidism, whereas 14.9% on older ASMs were affected (p = 0.35). Central hypothyroidism occurred in 10.3%, predominantly among users of zonisamide, phenobarbital, oxcarbazepine, and clobazam. Both older and newer ASM groups showed similar central hypothyroidism rates (9.6% versus 9.1%) CONCLUSION: Both older and newer ASMs exert clinically significant effects on thyroid homeostasis. Older ASMs were more often linked to subclinical hypothyroidism, while central hypothyroidism risk was comparable across ASM types. Annual thyroid screening is recommended to detect dysfunction early and prevent metabolic and cardiovascular complications.

105

News (Medical) associated with Clobazam

04 Sep 2026

·www.pharmaceutical-technology.com

Médunik and Biocodex sign exclusive agreement for Diacomit in Canada

Dravet syndrome is described as a rare lifelong neurological disorder marked by frequent, often treatment-resistant seizures from infancy. Credit: one photo / Shutterstock.com. Médunik Canada has entered an exclusive promotional services agreement with Biocodex for Diacomit, a medication approved in Canada as an add-on therapy for seizures associated with Dravet syndrome. The agreement gives Médunik Canada immediate responsibility for Diacomit’s sales, marketing, and medical affairs activities throughout the country. It aims to leverage Médunik Canada’s network and rare disease expertise to strengthen engagement with Canadian paediatric neurologists, epileptologists, and comprehensive epilepsy centres. When used together with clobazam and valproate, Diacomit is indicated by Health Canada for managing seizures associated with Dravet syndrome, a severe and rare developmental and epileptic encephalopathy. As part of the agreement, Médunik Canada will handle all commercial and medical engagement for the therapy while working to maintain consistency and reliability across the product’s supply chain and patient access. The goal is to expand educational programmes and support for Canada’s epilepsy community while ensuring ongoing access to the medication for eligible patients. Biocodex rare diseases international business head Hubert Chapellier said: “This alliance between our two companies marks a real turning point in our approach to Dravet syndrome in the Canadian market. “We are confident that our efforts will help patients and families better understand this complex condition. I am extremely excited about the partnership between Biocodex and Médunik Canada.” Dravet syndrome is described as a rare and lifelong neurological disorder, marked by frequent and often treatment-resistant seizures beginning in infancy. The condition can have a considerable impact on patients and their caregivers and typically needs the attention of specialised epilepsy care teams. Médunik Canada, part of Duchesnay Pharmaceutical Group (DPG), focuses on providing access to orphan drugs in Canada. DPG is headquartered in Blainville, Quebec, and operates several companies in both Canada and the US, offering a range of speciality and generic medicines.

License out/inDrug Approval

03 Sep 2026

·www.prnewswire.com

Médunik Canada enters into exclusive promotional services agreement with Biocodex for Diacomit® in Canada

Agreement expands support for Canadian healthcare professionals and families impacted by Dravet syndrome BLAINVILLE, QC, Sept. 3, 2026 /PRNewswire/ -- Médunik Canada, a Canadian owned and operated pharmaceutical company dedicated to improving the health and quality of life of people living with rare and debilitating diseases, part of Duchesnay Pharmaceutical Group, is pleased to announce that it has entered into an exclusive promotional services agreement with Biocodex for Diacomit®. Diacomit® is approved by Health Canada in conjunction with clobazam and valproate as adjunctive therapy for the treatment of seizures associated with Dravet syndrome, a rare and severe form of developmental and epileptic encephalopathy. Continue Reading Promotional Services Agreement between Médunik Canada and Biocodex Under the terms of the agreement, Médunik Canada assumes immediate and exclusive responsibility for all Canadian sales, marketing, and medical affairs activities related to Diacomit®. The partnership will leverage Médunik Canada's specialized rare disease infrastructure and expertise to strengthen engagement with Canadian pediatric neurologists, epileptologists, and specialized comprehensive epilepsy centers across the country. "Dravet syndrome requires highly specialized care, and we are excited to deploy our field teams to support Dravet specialists across the country. Our focus is to maximize the therapeutic reach of this medicine while ensuring that clinical support and medical education are closer to the specialists who need them," said Michael Gallo, Vice President, Regulatory & Medical Affairs, DPG. The agreement is designed to enhance commercial and medical engagement while preserving continuity and reliability across the product's supply chain and access infrastructure. "This alliance between our two companies marks a real turning point in our approach to Dravet syndrome in the Canadian market. We are confident that our efforts will help patients and families better understand this complex condition. I am extremely excited about the partnership between Biocodex and Médunik Canada," said Hubert Chapellier, Head of International Business, Biocodex Rare Diseases. Dravet syndrome is a rare, lifelong neurological disorder characterized by frequent and often treatment-resistant seizures that typically begin in infancy. The condition can significantly impact quality of life for patients and caregivers and generally requires management by specialized epilepsy care teams. Through this agreement, Médunik Canada and Biocodex aim to strengthen educational outreach and support for the Canadian epilepsy community while ensuring uninterrupted access to Diacomit® for eligible patients across Canada. ABOUT MÉDUNIK CANADA Médunik Canada's vision is to improve the health and quality of life of Canadians living with a rare and debilitating disease. Founded in December 2009, and part of Duchesnay Pharmaceutical Group, the company provides access to orphan drugs through strategic global partnerships as well as domestic and international research and development projects. For more information about Médunik Canada, please visit . Follow us on LinkedIn. ABOUT DUCHESNAY PHARMACEUTICAL GROUP Duchesnay Pharmaceutical Group (DPG), with its affiliated companies, is headquartered in Blainville, Quebec. The Group consists of six pharmaceutical companies to meet the needs of patients in Canada, the U.S. and abroad. The companies are Duchesnay (Canada) and Duchesnay USA, both dedicated to women's health; Médunik Canada and Medunik USA, which provide treatments for rare and debilitating diseases; and Analog Pharma Canada and Analog Pharma, specializing in orphan generic medications. From its state-of-the-art manufacturing plant, DPG exports its innovative treatments to more than 50 countries. DPG is one of the eight companies across the country chosen to participate in the Government of Canada's Global Hypergrowth Project. This appointment offers exclusive and personalized support for at least two years, in order to accelerate its growth to become an anchor firm in the Canadian economy. DPG is the winner of the 2024 Life Sciences Innovation Award by ADRIQ, the Association for the Development of Research and Innovation of Quebec, which recognizes DPG's healthy workplace culture and commitment to pharmaceutical innovation, while DPG president Éric Gervais is the recipient of the 2024 Bernard-Landry Award by ADRIQ which acknowledges his impactful leadership on Quebec's research and innovation ecosystem. DPG, through its proprietary research and development, and through exclusive partnerships, offers innovative treatments for a variety of medical conditions in women's health, urology, oncology and for rare diseases, plus lower-cost generic medications. DPG recognizes the dedication and professionalism of its employees and promotes a positive culture and flexible work environment. It is deeply committed to environmental responsibility and to giving back to the community through the support of various charitable organizations. For more information, please visit . Follow us on LinkedIn. SOURCE Médunik Canada 21% more press release views with Request a Demo

03 Sep 2026

·www.biospace.com

Médunik Canada enters into exclusive promotional services agreement with Biocodex for Diacomit® in Canada

Agreement expands support for Canadian healthcare professionals and families impacted by Dravet syndrome BLAINVILLE, QC , Sept. 3, 2026 /CNW/ -- Médunik Canada, a Canadian owned and operated pharmaceutical company dedicated to improving the health and quality of life of people living with rare and debilitating diseases, part of Duchesnay Pharmaceutical Group, is pleased to announce that it has entered into an exclusive promotional services agreement with Biocodex for Diacomit®. Diacomit® is approved by Health Canada in conjunction with clobazam and valproate as adjunctive therapy for the treatment of seizures associated with Dravet syndrome, a rare and severe form of developmental and epileptic encephalopathy. Under the terms of the agreement, Médunik Canada assumes immediate and exclusive responsibility for all Canadian sales, marketing, and medical affairs activities related to Diacomit®. The partnership will leverage Médunik Canada's specialized rare disease infrastructure and expertise to strengthen engagement with Canadian pediatric neurologists, epileptologists, and specialized comprehensive epilepsy centers across the country. "Dravet syndrome requires highly specialized care, and we are excited to deploy our field teams to support Dravet specialists across the country. Our focus is to maximize the therapeutic reach of this medicine while ensuring that clinical support and medical education are closer to the specialists who need them," said Michael Gallo, Vice President, Regulatory & Medical Affairs, DPG. ezstandalone.cmd.push(function () { ezstandalone.showAds(131); }); The agreement is designed to enhance commercial and medical engagement while preserving continuity and reliability across the product's supply chain and access infrastructure. "This alliance between our two companies marks a real turning point in our approach to Dravet syndrome in the Canadian market. We are confident that our efforts will help patients and families better understand this complex condition. I am extremely excited about the partnership between Biocodex and Médunik Canada," said Hubert Chapellier, Head of International Business, Biocodex Rare Diseases. Dravet syndrome is a rare, lifelong neurological disorder characterized by frequent and often treatment-resistant seizures that typically begin in infancy. The condition can significantly impact quality of life for patients and caregivers and generally requires management by specialized epilepsy care teams. Through this agreement, Médunik Canada and Biocodex aim to strengthen educational outreach and support for the Canadian epilepsy community while ensuring uninterrupted access to Diacomit® for eligible patients across Canada. ezstandalone.cmd.push(function () { ezstandalone.showAds(132); }); ABOUT MÉDUNIK CANADA Médunik Canada's vision is to improve the health and quality of life of Canadians living with a rare and debilitating disease. Founded in December 2009, and part of Duchesnay Pharmaceutical Group, the company provides access to orphan drugs through strategic global partnerships as well as domestic and international research and development projects. For more information about Médunik Canada, please visit . Follow us on LinkedIn . ezstandalone.cmd.push(function () { ezstandalone.showAds(133); }); ABOUT DUCHESNAY PHARMACEUTICAL GROUP Duchesnay Pharmaceutical Group (DPG), with its affiliated companies, is headquartered in Blainville, Quebec. The Group consists of six pharmaceutical companies to meet the needs of patients in Canada, the U.S. and abroad. The companies are Duchesnay (Canada) and Duchesnay USA, both dedicated to women's health; Médunik Canada and Medunik USA, which provide treatments for rare and debilitating diseases; and Analog Pharma Canada and Analog Pharma, specializing in orphan generic medications. From its state-of-the-art manufacturing plant, DPG exports its innovative treatments to more than 50 countries. DPG is one of the eight companies across the country chosen to participate in the Government of Canada's Global Hypergrowth Project. This appointment offers exclusive and personalized support for at least two years, in order to accelerate its growth to become an anchor firm in the Canadian economy. DPG is the winner of the 2024 Life Sciences Innovation Award by ADRIQ, the Association for the Development of Research and Innovation of Quebec, which recognizes DPG's healthy workplace culture and commitment to pharmaceutical innovation, while DPG president Éric Gervais is the recipient of the 2024 Bernard-Landry Award by ADRIQ which acknowledges his impactful leadership on Quebec's research and innovation ecosystem. ezstandalone.cmd.push(function () { ezstandalone.showAds(134); }); DPG, through its proprietary research and development, and through exclusive partnerships, offers innovative treatments for a variety of medical conditions in women's health, urology, oncology and for rare diseases, plus lower-cost generic medications. DPG recognizes the dedication and professionalism of its employees and promotes a positive culture and flexible work environment. It is deeply committed to environmental responsibility and to giving back to the community through the support of various charitable organizations. For more information, please visit . Follow us on LinkedIn . View original content to download multimedia: ezstandalone.cmd.push(function () { ezstandalone.showAds(135); }); SOURCE Médunik Canada

License out/inOrphan Drug

100 Deals associated with Clobazam

External Link

KEGG	Wiki	ATC	Drug Bank
D01253	Clobazam	N05BA09	DB00349

R&D Status

Approved

10 top approved records.

to view more data

Indication	Country/Location	Organization	Date
Lennox Gastaut Syndrome	United States	Lundbeck Pharmaceuticals Ltd.	21 Oct 2011
Seizures	Japan	Sumitomo Pharma Co., Ltd.	10 Mar 2000
Anxiety Disorders	Australia	Sanofi-Aventis Australia Pty Ltd.	01 Aug 1991
Epilepsy	Australia	Sanofi-Aventis Australia Pty Ltd.	01 Aug 1991

Developing

10 top R&D records.

to view more data

Indication	Highest Phase	Country/Location	Organization	Date
Epilepsies, Myoclonic	Phase 3	United States	H. Lundbeck A/S	01 Mar 2015
Epilepsies, Myoclonic	Phase 3	Mexico	H. Lundbeck A/S	01 Mar 2015
Epilepsia Partialis Continua	Phase 3	United States	Lundbeck LLC	01 Jul 2014
Epilepsy, Generalized	Phase 3	United States	Lundbeck LLC	01 Aug 2007
Epilepsy, Generalized	Phase 3	Australia	Lundbeck LLC	01 Aug 2007
Epilepsy, Generalized	Phase 3	Belarus	Lundbeck LLC	01 Aug 2007
Epilepsy, Generalized	Phase 3	India	Lundbeck LLC	01 Aug 2007
Epilepsy, Generalized	Phase 3	Lithuania	Lundbeck LLC	01 Aug 2007

Clinical Result

Indication

Phase

Evaluation

View All Results

Study	Phase	Population	Analyzed Enrollment	Group	Results	Evaluation	Publication Date


AAN2026	Not Applicable	CDKL5 Deficiency Disorder CDKL5 gene variants	584	Levetiracetam	glmrrxieem(uyqhpvxvbf) = ckkcnpqkmn zfsyaveqzu (lbkzavuaup, 17.2 - 21.1) View more	Positive	25 Apr 2026
AAN2026	Not Applicable	CDKL5 Deficiency Disorder CDKL5 gene variants	584	Clobazam	dvsvdasope(xnvargbwax) = vrvolifqns ehhcjziyls (ermgpvopqn )	Positive	25 Apr 2026
Company_Website Manual	Not Applicable	Epilepsy \| Lennox Gastaut Syndrome	-	Sympazan (clobazam) Oral Film (Epilepsy)	wfcezhkrjp(wodfrlvisw) = more often switched from clobazam tablets or suspension, and had higher cannabidiol use than those in the epilepsy group. gstuxgpowf (agnvrxcneh )	Positive	15 Sep 2025
Company_Website Manual	Not Applicable	Epilepsy \| Lennox Gastaut Syndrome	-	Sympazan (clobazam) Oral Film (Lennox-Gastaut Syndrome)		Positive	15 Sep 2025
ASCO2025	Not Applicable	Epilepsy Add-on	48	Clobazam	osbabkjqob(rwkktmytsv) = uvsnaseibu ojsefbzylu (lojgydyoek ) View more	Positive	30 May 2025
NCMP-08 (SNO2022)	Not Applicable	Glioma	1,435	Levetiracetam + Valproic Acid + Clobazam	kdyljxjafq(xisdzjiudx) = dqfqohxsll ttmyoxhbyu (xzfqmtkafo, 48 - 78)	Positive	14 Nov 2022
NCMP-08 (SNO2022)	Not Applicable	Glioma	1,435	Other ASM Triple Therapy	kdyljxjafq(xisdzjiudx) = hkgngvctsx ttmyoxhbyu (xzfqmtkafo, 47 - 75)	Positive	14 Nov 2022
Pubmed \| Epilepsy Behav	Not Applicable	Epilepsy Add-on	475	Clobazam	qrdezkldgb(hltlrghzat) = lclorpuvxf adcybezgzf (pwoquaywjv )	-	02 Apr 2022
NCT03371836 (CTgov)	Phase 4	Epilepsy \| Anxiety Disorders	20	Clobazam	zzemltlmaz(ngfbuaukdh) = costzbipew tppeptqiny (rqawnfkrew, dqwinhzoca - ndhdyhghar)	-	04 Mar 2021
AAN2019	Not Applicable	Epilepsy	196	Clobazam	zjnrcfszhx(eedeslihmk) = pevnakcfby obatzhliul (daogmiyucw ) View more	Positive	09 Apr 2019
AAN2019	Not Applicable	Drug Resistant Epilepsy	417	Clobazam	bihwbxuptp(mgzxloarfn) = mzudquibyj xxstbwwezt (ucpccbinsg ) View more	Positive	09 Apr 2019
NCT00518713 (OV-1017, OV-1012, Study 301, AAN2018)	Phase 3	Epilepsies, Myoclonic CYP3A4	-	Clobazam 1.5 mg/kg	fkwrgzorvu(jgvqjsexgq) = zohnjzeaxj nhvcmpzvou (jynqcfcbbu ) View more	-	10 Apr 2018
NCT00518713 (OV-1017, OV-1012, Study 301, AAN2018)	Phase 3	Epilepsies, Myoclonic CYP3A4	-	Clobazam 2 mg/kg	fkwrgzorvu(jgvqjsexgq) = vlqthekqkz nhvcmpzvou (jynqcfcbbu ) View more	-	10 Apr 2018
NCT02187809 (CTgov)	Phase 3	Epilepsies, Myoclonic	3	Clobazam	jbhdvkihuw = uhsvjdqrcx cgbhvmkxvl (dlfmmwexjj, rhsjrpptje - ssxhwnekkr) View more	-	15 Feb 2017

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