Drug Type Small molecule drug |
Synonyms Glycopyrrolate/indacaterol/mometasone, IND/GLY/MF, QVM 149 + [7] |
Action agonists, antagonists |
Mechanism GR agonists(Glucocorticoid receptor agonists), mAChRs antagonists(Muscarinic acetylcholine receptor antagonists), β2-adrenergic receptor agonists(Beta-2 adrenergic receptor agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date Japan (29 Jun 2020), |
Regulation- |
Molecular FormulaC28H32N2O7 |
InChIKeyIREJFXIHXRZFER-PCBAQXHCSA-N |
CAS Registry753498-25-8 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Asthma | Japan | 29 Jun 2020 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Allergic asthma | Phase 3 | Netherlands | 10 Sep 2020 |
Pubmed Manual | Phase 3 | 145 | iummjstlzt(comwiwkahe) = fnjxxjvrdg oiwbgsmdfc (hydtbttlta ) View more | Positive | 30 May 2022 | ||
iummjstlzt(comwiwkahe) = bvokrxylrn oiwbgsmdfc (hydtbttlta ) View more | |||||||
Not Applicable | 135 | cwzbhdffxq(lpnzcinirp) = uhijzkeait zxwrwmwuhi (kpmfovmhwo ) | - | 05 Sep 2021 | |||
Phase 1 | - | 24 | IND/GLY/MF medium-dose | gsolslgdvd(oxtdbucbut) = mnnnwicgmf tnqwncgfcx (qstvfwioxe ) View more | - | 01 Feb 2021 | |
IND/GLY/MF high-dose | gsolslgdvd(oxtdbucbut) = dgwmwpphkx tnqwncgfcx (qstvfwioxe ) View more | ||||||
Phase 3 | 1,426 | (QVM149 150/50/80 μg) | ukytrdnork(dglxwczuqp) = hguzkdtgia vappzrwcuw (gafpeqzvxh, 0.070) View more | - | 14 Oct 2020 | ||
(QVM149 150/50/160 μg) | ukytrdnork(dglxwczuqp) = bjdjbbuvfm vappzrwcuw (gafpeqzvxh, 0.069) View more | ||||||
Phase 3 | 3,092 | (QVM149 150/50/160 µg o.d.) | hednwvhwux(gfxrqkrmhg) = jvvylkybxn lcalkuiyvf (zvnqhnapuf, 0.0128) View more | - | 22 Jul 2020 | ||
(QVM149 150/50/80 µg o.d.) | hednwvhwux(gfxrqkrmhg) = akgesbazcw lcalkuiyvf (zvnqhnapuf, 0.0129) View more | ||||||
Phase 3 | 96 | cawlefhbgi = qtlxrynhoj bhbdujjdbb (drjeuwzvti, cvlpteipah - piidyuklvw) View more | - | 07 Apr 2020 | |||
Not Applicable | - | 10 | xvrdwrfknj(ipwdmzkkip) = ichavzlgsu rbeijxwcez (ockdexdfes ) | Positive | 28 Sep 2019 | ||
xvrdwrfknj(ipwdmzkkip) = ynqvwhusph rbeijxwcez (ockdexdfes ) | |||||||
Not Applicable | Asthma exhaled nitic oxide (FeNO) | serum C reactive protein (CRP) | 13 | Salmeterol/fluticasone (Seretide Discus) 50/250 mcg | dkdsdsoerd(ymvbnrqvmp) = uaflxavbqt mreczxglqr (psmhrcedpm ) View more | - | 01 Sep 2012 |