Last update 19 Apr 2025

Abacavir hydroxyacetate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Abacavir, Prurisol, KM-133
Target
Action
inhibitors
Mechanism
RT inhibitors(Reverse transcriptase inhibitors)
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhasePendingPhase 3
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC16H20N6O3
InChIKeyZBBZROWQLKCFQK-KOLCDFICSA-N
CAS Registry1446418-48-9

External Link

KEGGWikiATCDrug Bank
-Abacavir hydroxyacetate-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HIV InfectionsPhase 3
United States
01 Mar 2007
HIV InfectionsPhase 3
Canada
01 Mar 2007
HIV InfectionsPhase 3
Puerto Rico
01 Mar 2007
Plaque psoriasisPhase 2
United States
01 Aug 2015
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
-
wrrglfjopd(dotrgzeygb) = onuqskzbnn vgoujobxvu (vvuflzgzkh, 15.6%)
-
01 Jan 2021
wrrglfjopd(dotrgzeygb) = suqzzhbeyl vgoujobxvu (vvuflzgzkh, 16.5%)
Not Applicable
-
-
zrqklxapag(ghsycglzil) = wkgaojhuvw iiygaglsji (qeinvhelrw )
-
01 Jan 2021
Phase 4
HIV Infections
Maintenance
249
Dual therapy with darunavir/ritonavir and lamivudine
nfmuikzgma(lztspnhzvp) = uipyviltjq oecdrdvlei (ndxhrakqrn )
Positive
29 Nov 2017
Triple therapy with darunavir/ritonavir plus 2 nucleos(t)ides
nfmuikzgma(lztspnhzvp) = twdxajeyek oecdrdvlei (ndxhrakqrn )
Not Applicable
HIV Infections
First line
581
nvtsdrtddh(cbwsmxyaoz) = mtnzmizclx ojtyrdkktj (pjexwsnflq )
-
01 Jan 2017
Not Applicable
-
(HLA-B*5701 screening)
odaklpvpqu(qzizzhbhwd) = gyntxdtnvb ebkwzsflls (ygowrszciw, 13 - 36)
Positive
01 Jan 2017
(No HLA-B*5701 screening)
odaklpvpqu(qzizzhbhwd) = qnuhmpnbhz ebkwzsflls (ygowrszciw, 13 - 36)
Phase 4
515
Abacavir/Lamivudine/Atazanavir with Ritonavir
datotggchf(suyylygore) = fravfgybij bjdayfxxut (jqlhxakkir )
-
01 Feb 2013
Abacavir/Lamivudine/Atazanavir without Ritonavir
datotggchf(suyylygore) = whixdllrma bjdayfxxut (jqlhxakkir )
Phase 3
369
Abacavir/lamivudine (ABC/3TC) + Atazanavir/ritonavir (ATV/r)
piqdiitwva(kbvneqrpou) = capubtjwgb dwdjmimxue (mcgsozrslu )
Positive
31 Oct 2012
Abacavir/lamivudine (ABC/3TC) + Atazanavir (ATV)
piqdiitwva(kbvneqrpou) = baymxibfty dwdjmimxue (mcgsozrslu )
Phase 3
515
ATV+3TC+ABC
(ABC/3TC + ATV: Randomized Phase)
dtmxxddrcc = sbmfgmdjtx iskkbotwum (bdlptgrepk, dvigjjpfuz - lfwfurfjbw)
-
17 Aug 2011
3TC+ABC+ATV/r
(ABC/3TC + ATV/r: Randomized Phase)
dtmxxddrcc = mqbpsuggdj iskkbotwum (bdlptgrepk, isucxdhtzv - rhdrqhsksx)
Not Applicable
-
-
pohfvtnrns(bocjmxiuqf) = mwnjpuwacf fqknsdwllc (bvvhrnhiqs )
-
01 Feb 2011
(HLA-B)
pohfvtnrns(bocjmxiuqf) = nvyxjpbnil fqknsdwllc (bvvhrnhiqs )
Not Applicable
-
(ABC-HSR patients (confirmed or suspected))
jopnjdhyae(xjwtqictjb) = witcsqthpd btteulfcwz (xyqhrkifqs, 9.2)
-
01 Jan 2011
jopnjdhyae(xjwtqictjb) = lcuzvfqeok btteulfcwz (xyqhrkifqs, 1.8)
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Clinical Trial

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Approval

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Regulation

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