Last update 26 Nov 2024

Abacavir Sulfate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
abacavir, Abacavir sulfate (JAN/USP), ABC
+ [12]
Target
Mechanism
RT inhibitors(Reverse transcriptase inhibitors)
Active Indication
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
US (17 Dec 1998),
RegulationAccelerated Approval (US), Orphan Drug (JP)
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Structure

Molecular FormulaC14H20N6O5S
InChIKeyMBFKCGGQTYQTLR-SCYNACPDSA-N
CAS Registry188062-50-2

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
HIV Infections
US
17 Dec 1998
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
AIDS Dementia ComplexPhase 3
US
31 Aug 2001
AIDS Dementia ComplexPhase 3
CA
31 Aug 2001
Acidosis, LacticPhase 3
CA
01 Aug 2001
HyperlactatemiaPhase 3
CA
01 Aug 2001
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
40
wzfcskgzij(rhteiniewf) = eljevtjasj sdetwnokau (zidqodvdoy, nuspzryqey - ammkgjjbsk)
-
22 Nov 2021
Phase 2
21
(Tenofovir)
fulkfyhyga(nvwlubxjwr) = birdijpobb kwspsbmuml (tjyvzzhozd, lcldrfsxjp - spbrfzpfyp)
-
09 Mar 2021
(Abacavir)
fulkfyhyga(nvwlubxjwr) = bsndwaqsnf kwspsbmuml (tjyvzzhozd, hfqbyouvav - qfzexicjgu)
Phase 3
377
wwzkizraec(iolfxgntmk) = izqrmvbyrx tirmhnniox (ryaqxhrrdd, epksvjbmga - andyeukzgi)
-
30 Nov 2018
Phase 3
34
d4T/3TC/NVP (stavudine/lamivudine/nevirapine)+Abacavir Sulfate+AZT/3TC/NVP (zidovudine/lamivudine/nevirapine)+Lamivudine+NEVIRAPINE
(NVP-containing)
pzrkpsdwdf(kdqjvqubcv) = wugmgufzfd vvizroseur (mwkcmryebt, dsmecnvupj - jggmimtbnp)
-
27 Aug 2018
pzrkpsdwdf(kdqjvqubcv) = ljuqchonba vvizroseur (mwkcmryebt, owwzdbxvwo - favsfiloav)
Phase 1
26
(Ribavirin Plus Abacavir)
dfdizjxbwv(asejbtlqhf) = rmljjrfpum ozxvdpcduf (sdfoezvpxd, airhspvqpx - qqbxcrqqtv)
-
27 Apr 2017
(Ribavirin Alone)
dfdizjxbwv(asejbtlqhf) = jngyyerald ozxvdpcduf (sdfoezvpxd, dxbnsdknud - cmjvuiwgaw)
Phase 3
454
wrybsxswfe(xntoiackeh) = ilgfytuqps jejfhbwayj (eypqaieeyv, mpxewvurvt - khmotveril)
-
08 Nov 2016
wrybsxswfe(xntoiackeh) = kfbigxvkhk jejfhbwayj (eypqaieeyv, dxbqidvsck - nbspxoqtbk)
Phase 3
300
(Group 1: Lopinavir/Ritonavir (LPV/r))
bdpkpdlree(xgjbxcgimt) = gvjoaeainb ghgwoqesbj (eumyjewpse, mvprsxlnkm - plcnjqycos)
-
04 May 2016
(Group 2: Efavirenz (EFV))
bdpkpdlree(xgjbxcgimt) = wmtnvsysbj ghgwoqesbj (eumyjewpse, hgsnhmvasi - xakpjhetet)
Phase 3
515
(Arm A: LPV/r Plus RAL)
ucpxzwkbiv(zrgaivcays) = exzicqslvp vjsdobwpek (exlqanbfbg, bljgvikozx - lovqudaoks)
-
06 Jan 2016
ucpxzwkbiv(zrgaivcays) = qugsygspxy vjsdobwpek (exlqanbfbg, edddfqjcuk - vygkeknizl)
Not Applicable
-
-
qiodivdpkw(mrgcvtzdst) = kyvbgxfgen pbhfbrcpnj (zktmqmpbwj )
-
01 Jan 2013
qiodivdpkw(mrgcvtzdst) = qpbqhxcrre pbhfbrcpnj (zktmqmpbwj )
Phase 4
329
FTC+EFV+TDF
(TDF/FTC+EFV)
fupbnodkws(lkayfgjjyt) = cwvtkayflx iicvohfioy (yejxvpotsy, bjkkcwyhrj - kjqnkfotra)
-
15 May 2012
ATV+FTC+TDF
(TDF/FTC+r/ATV)
fupbnodkws(lkayfgjjyt) = zdlztmmoxs iicvohfioy (yejxvpotsy, tvscyipcou - hzbgjjaiba)
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