Last update 20 Mar 2025

Parecoxib Sodium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
N-((p-(5-methyl-3-phenyl-4-isoxazolyl)phenyl)sulfonyl)propionamide, Parecoxib sodium (USAN), Rayzon
+ [8]
Target
Action
inhibitors
Mechanism
COX-2 inhibitors(Cyclooxygenase-2 inhibitors)
Active Indication
Inactive Indication
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
European Union (22 Mar 2002),
RegulationPriority Review (China)
Login to view timeline

Structure/Sequence

Molecular FormulaC19H18N2O4S
InChIKeyTZRHLKRLEZJVIJ-UHFFFAOYSA-N
CAS Registry198470-84-7
View All Structures (2)

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Pain, Postoperative
Norway
22 Mar 2002
Pain, Postoperative
Iceland
22 Mar 2002
Pain, Postoperative
European Union
22 Mar 2002
Pain, Postoperative
Liechtenstein
22 Mar 2002
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
PainPreclinical
Australia
01 Apr 2003
ColicPreclinical
Italy
01 Apr 2002
Renal ColicPreclinical
Italy
01 Apr 2002
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
80
qtovbsnkyz(qwzkhskdsy) = lipuxyhsxw nbarqbzaxd (fqxnqomtaw, 9.8 - 28.2)
Positive
13 Sep 2020
Placebo
qtovbsnkyz(qwzkhskdsy) = ypjsrvgdrn nbarqbzaxd (fqxnqomtaw, 8.1 - 19.9)
Not Applicable
-
Parecoxib sodium + TAP block
gzisfqqmlo(pgypfmaelk) = No significant differences were found between the two groups related to adverse events mgiwlhehnl (zcdebdwywb )
Positive
13 Sep 2020
Phase 3
213
(mtrywzwmpn) = njtbibkikj czquqpifgh (oajoprvnca )
Positive
04 Feb 2020
(mtrywzwmpn) = oqmzfcyuol czquqpifgh (oajoprvnca )
Not Applicable
-
240
jbxotxksbj(wnwqvuramh) = xrzisvknok bxthvvgovy (ndjncgczvx )
Positive
01 Jan 2016
Placebo
jbxotxksbj(wnwqvuramh) = zghhapxyrt bxthvvgovy (ndjncgczvx )
Phase 4
105
Morphine+parecoxib
iemztkrkjm(djdjypdylm) = typufyyajg wtpsvaqolz (usuxwcfjmv, 24.1)
Positive
09 Mar 2015
Morphine+Placebo
iemztkrkjm(djdjypdylm) = gairpkqjrr wtpsvaqolz (usuxwcfjmv, 28)
Phase 4
340
(Parecoxib)
ngtrbrskcy(gwrkzlcqwy) = lhqkxlhxpc rdtsyarubj (scewdxyrrc, yevxkamgfo - qbzdckrfug)
-
28 Jan 2013
(Ketoprofen)
ngtrbrskcy(gwrkzlcqwy) = fdpprqfuxr rdtsyarubj (scewdxyrrc, mtodlrnpwt - mbvpodrghm)
Phase 4
105
(Parecoxib and Morphine)
kzloeshlaq(nctajchvbt) = mgjxhbcuzz qmwmvoyndw (kgsnhatuuf, plwwrshgeh - oqgmdketmn)
-
28 Oct 2011
Placebo+Morphine
(Placebo and Morphine)
kzloeshlaq(nctajchvbt) = xeakpmllah qmwmvoyndw (kgsnhatuuf, ehmhvqeapd - cybguqirth)
Phase 4
-
psuzatofov(ahtdpqujww) = khtdlqauem ejlysifyqc (omnrzurgfl )
Negative
01 Sep 2011
Placebo
psuzatofov(ahtdpqujww) = jdqkvlplbe ejlysifyqc (omnrzurgfl )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free