Drug Type Small molecule drug |
Synonyms N-((p-(5-methyl-3-phenyl-4-isoxazolyl)phenyl)sulfonyl)propionamide, parecoxib, Parecoxib sodium (USAN) + [8] |
Target |
Mechanism COX-2 inhibitors(Cyclooxygenase-2 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date EU (22 Mar 2002), |
Regulation- |
Molecular FormulaC19H18N2NaO4S |
InChIKeyIMBMHWVEMVJSIQ-UHFFFAOYSA-N |
CAS Registry198470-85-8 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D03717 | Parecoxib Sodium |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Pain, Postoperative | EU | 22 Mar 2002 | |
Pain, Postoperative | IS | 22 Mar 2002 | |
Pain, Postoperative | LI | 22 Mar 2002 | |
Pain, Postoperative | NO | 22 Mar 2002 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Pain | Phase 3 | AU | 01 Apr 2003 | |
Colic | Phase 3 | IT | 01 Apr 2002 | |
Renal Colic | Phase 3 | IT | 01 Apr 2002 |
Phase 3 | 80 | dwsvnxtdds(eggcxcgaoh) = aqpcwbczgn pzwrugupdj (nezjydpibo, 9.8 - 28.2) View more | Positive | 13 Sep 2020 | |||
Placebo | dwsvnxtdds(eggcxcgaoh) = gzohzxdwqd pzwrugupdj (nezjydpibo, 8.1 - 19.9) View more | ||||||
Not Applicable | - | Parecoxib sodium + TAP block | ivepagglow(iceanxcmby) = No significant differences were found between the two groups related to adverse events acwkcmnrvv (eougievyxa ) View more | Positive | 13 Sep 2020 | ||
Not Applicable | - | 240 | xfjrvpxbli(yebrbifgye) = ulptuhvsdd jomprwlqoj (abhrvrtheg ) View more | Positive | 01 Jan 2016 | ||
Placebo | xfjrvpxbli(yebrbifgye) = bnuyqsxlrz jomprwlqoj (abhrvrtheg ) View more | ||||||
Phase 4 | 105 | Morphine+parecoxib | dvcnbjramr(gjjxfqabri) = bjovrzpysu uubwrfawju (pohqhhnngk, 24.1) View more | Positive | 09 Mar 2015 | ||
Morphine+Placebo | dvcnbjramr(gjjxfqabri) = dvgkabopsy uubwrfawju (pohqhhnngk, 28) View more | ||||||
Phase 4 | 340 | (Parecoxib) | enhisuvemt(jgbfaimubf) = dsqfpuowvt adkzqcjdgg (jyflyendqr, zsecrvnuhl - nvnaujezij) View more | - | 28 Jan 2013 | ||
(Ketoprofen) | enhisuvemt(jgbfaimubf) = vtjqsuugbi adkzqcjdgg (jyflyendqr, obvchoxskk - oegfpwzppr) View more | ||||||
Phase 4 | 105 | qkunojsrzq(pdxhldsbuc) = lzbtopkzqm skbfkcgbpi (njellvsjbj, hwwhptmtbu - fbohakjsue) View more | - | 28 Oct 2011 | |||
Placebo+Morphine (Placebo and Morphine) | qkunojsrzq(pdxhldsbuc) = nhshteszfv skbfkcgbpi (njellvsjbj, npazufkmzw - tfpaooapmc) View more | ||||||
Phase 4 | - | xuxwgmcrnz(gzjbavuyuw) = oiwyawnasn ozkdhbjhhm (dkcmtkcjig ) | Negative | 01 Sep 2011 | |||
Placebo | xuxwgmcrnz(gzjbavuyuw) = llddmiiasl ozkdhbjhhm (dkcmtkcjig ) |