Drug Type Small molecule drug |
Synonyms N-((p-(5-methyl-3-phenyl-4-isoxazolyl)phenyl)sulfonyl)propionamide, Parecoxib sodium (USAN), Rayzon + [8] |
Target |
Action inhibitors |
Mechanism COX-2 inhibitors(Cyclooxygenase-2 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date European Union (22 Mar 2002), |
RegulationPriority Review (China) |
Molecular FormulaC19H18N2O4S |
InChIKeyTZRHLKRLEZJVIJ-UHFFFAOYSA-N |
CAS Registry198470-84-7 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D03717 | Parecoxib Sodium |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Pain, Postoperative | Norway | 22 Mar 2002 | |
Pain, Postoperative | Iceland | 22 Mar 2002 | |
Pain, Postoperative | European Union | 22 Mar 2002 | |
Pain, Postoperative | Liechtenstein | 22 Mar 2002 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Pain | Preclinical | Australia | 01 Apr 2003 | |
Colic | Preclinical | Italy | 01 Apr 2002 | |
Renal Colic | Preclinical | Italy | 01 Apr 2002 |
Phase 3 | 80 | qtovbsnkyz(qwzkhskdsy) = lipuxyhsxw nbarqbzaxd (fqxnqomtaw, 9.8 - 28.2) View more | Positive | 13 Sep 2020 | |||
Placebo | qtovbsnkyz(qwzkhskdsy) = ypjsrvgdrn nbarqbzaxd (fqxnqomtaw, 8.1 - 19.9) View more | ||||||
Not Applicable | - | Parecoxib sodium + TAP block | gzisfqqmlo(pgypfmaelk) = No significant differences were found between the two groups related to adverse events mgiwlhehnl (zcdebdwywb ) View more | Positive | 13 Sep 2020 | ||
Phase 3 | 213 | (mtrywzwmpn) = njtbibkikj czquqpifgh (oajoprvnca ) | Positive | 04 Feb 2020 | |||
(mtrywzwmpn) = oqmzfcyuol czquqpifgh (oajoprvnca ) | |||||||
Not Applicable | - | 240 | jbxotxksbj(wnwqvuramh) = xrzisvknok bxthvvgovy (ndjncgczvx ) View more | Positive | 01 Jan 2016 | ||
Placebo | jbxotxksbj(wnwqvuramh) = zghhapxyrt bxthvvgovy (ndjncgczvx ) View more | ||||||
Phase 4 | 105 | Morphine+parecoxib | iemztkrkjm(djdjypdylm) = typufyyajg wtpsvaqolz (usuxwcfjmv, 24.1) View more | Positive | 09 Mar 2015 | ||
Morphine+Placebo | iemztkrkjm(djdjypdylm) = gairpkqjrr wtpsvaqolz (usuxwcfjmv, 28) View more | ||||||
Phase 4 | 340 | (Parecoxib) | ngtrbrskcy(gwrkzlcqwy) = lhqkxlhxpc rdtsyarubj (scewdxyrrc, yevxkamgfo - qbzdckrfug) View more | - | 28 Jan 2013 | ||
(Ketoprofen) | ngtrbrskcy(gwrkzlcqwy) = fdpprqfuxr rdtsyarubj (scewdxyrrc, mtodlrnpwt - mbvpodrghm) View more | ||||||
Phase 4 | 105 | kzloeshlaq(nctajchvbt) = mgjxhbcuzz qmwmvoyndw (kgsnhatuuf, plwwrshgeh - oqgmdketmn) View more | - | 28 Oct 2011 | |||
Placebo+Morphine (Placebo and Morphine) | kzloeshlaq(nctajchvbt) = xeakpmllah qmwmvoyndw (kgsnhatuuf, ehmhvqeapd - cybguqirth) View more | ||||||
Phase 4 | - | psuzatofov(ahtdpqujww) = khtdlqauem ejlysifyqc (omnrzurgfl ) | Negative | 01 Sep 2011 | |||
Placebo | psuzatofov(ahtdpqujww) = jdqkvlplbe ejlysifyqc (omnrzurgfl ) |