Drug Type Small molecule drug |
Synonyms Lanabecestat (USAN), Lanabecestat Camsylate + [3] |
Target |
Mechanism BACE1 inhibitors(Beta-secretase 1 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhasePhase 3 |
First Approval Date- |
RegulationSpecial Review Project (CN) |
Molecular FormulaC26H28N4O |
InChIKeyWKDNQONLGXOZRG-HRNNMHKYSA-N |
CAS Registry1383982-64-6 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D10946 | Lanabecestat | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Alzheimer Disease | Phase 3 | US | 01 Jul 2016 | |
Alzheimer Disease | Phase 3 | CZ | 01 Jul 2016 | |
Alzheimer Disease | Phase 3 | RU | 01 Jul 2016 | |
Alzheimer Disease | Phase 3 | NL | 01 Jul 2016 | |
Alzheimer Disease | Phase 3 | GB | 01 Jul 2016 | |
Alzheimer Disease | Phase 3 | JP | 01 Jul 2016 | |
Alzheimer Disease | Phase 3 | DE | 01 Jul 2016 | |
Alzheimer Disease | Phase 3 | MX | 01 Jul 2016 | |
Alzheimer Disease | Phase 3 | PT | 01 Jul 2016 | |
Alzheimer Disease | Phase 3 | IT | 01 Jul 2016 |
Phase 3 | 1,722 | xbwzsmhqqf(iktasgqqfc) = hqgxfwrxlb qakmnujgcj (uefqlnidck, picjpxgswu - ndvkherqib) View more | - | 06 Aug 2019 | |||
Phase 2/3 | 2,218 | Placebo (Placebo) | ajogkjfzal(gkecgrwrww) = pgbxcougjk pgxzbfbdvv (wllzyeiqkg, uzlstljgnl - bbgbeztguk) View more | - | 06 Aug 2019 | ||
(Lanabecestat 50 mg) | ajogkjfzal(gkecgrwrww) = kevaaffmts pgxzbfbdvv (wllzyeiqkg, sichcqgjrz - wiqvgordjc) View more | ||||||
Phase 3 | 421 | (AZES Placebo/AZFD Lanabecestat 20 mg) | gkgrqgdfob(jubpbnmsyg) = mkphrijydy tbfeuevvlq (lflwwwssjx, efvbirwdat - ukaiydbqqw) View more | - | 05 Jul 2019 | ||
(AZES Placebo/AZFD Lanabecestat 50 mg) | gkgrqgdfob(jubpbnmsyg) = faievdanvc tbfeuevvlq (lflwwwssjx, pexxbofbxx - aepdxyliug) View more | ||||||
Phase 1 | - | 82 | (Cohort A) | nctnsvpbvc(mdgbqpmuna) = thuhdbivtg arvmhezefw (nlmxtamgae, snhmbldmfg - sfhwqykagl) View more | - | 22 Mar 2019 | |
(Cohort B) | lcfejbeoiu(jmrgwtwtmr) = irydhcmxhk xandnluinf (raonjcvucj, aysgjdsmux - creebglgse) View more | ||||||
Phase 1 | - | 8 | (LY3314814) | wyqajkpiid(pnoqruliby) = pshjqbgxmz ijxoeivbwg (latpnvnwth, rloddrpdeo - gidtzvcbrw) View more | - | 22 Mar 2019 | |
([13C415N3] LY3314814) | wyqajkpiid(pnoqruliby) = niiltzjmcn ijxoeivbwg (latpnvnwth, usjoyojlnx - rqyivoxfre) View more | ||||||
Phase 2/3 | 84 | rvtqcorste(jgdymkvaps) = zdplcyugsc poizuyjdvu (egbzjszygb ) View more | - | 01 Jul 2016 |