Last update 01 Apr 2025

Midazolam Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Midazolam hydrochloride (USAN), Ozalin, NSC-751451
+ [8]
Action
agonists
Mechanism
GABAA receptor agonists(Gamma-aminobutyric acid A receptor agonists)
Inactive Indication-
Originator Organization
Drug Highest PhaseApproved
First Approval Date
United States (20 Dec 1985),
RegulationPriority Review (China)
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Structure/Sequence

Molecular FormulaC18H14Cl2FN3
InChIKeyPLYSCVSCYOQVRP-UHFFFAOYSA-N
CAS Registry59467-96-8

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Status Epilepticus
United States
14 Sep 2018
Seizures
European Union
04 Sep 2011
Seizures
Iceland
04 Sep 2011
Seizures
Liechtenstein
04 Sep 2011
Seizures
Norway
04 Sep 2011
Anesthesia
United States
20 Dec 1985
Sedation
United States
20 Dec 1985
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
37
(Midazolam, Hydroxyzine, Meperidine)
tetgznziie = zjjiccftbp qrsrrzegnj (ledampkuwo, vqazjfpkyp - kuxbexbeop)
-
05 Dec 2023
(Midazolam, Hydroxyzine)
tetgznziie = skgzkdoejf qrsrrzegnj (ledampkuwo, zchzkmiaba - yqgkmeeago)
Phase 3
3
rrmoyzkbsr = gzbcvinbpi jswjeokwtn (zggjsuzpac, pttjhwjtck - kdvcatgkdm)
-
14 Sep 2021
Phase 3
25
srnzlnavov = zmtmikspby kcstcyjnyp (tirrpyoksb, bkkxxdkanj - zphkofznvw)
-
31 Jul 2020
Phase 1
32
Dexmedetomidine+Peripheral nerve stimulation
(Dexmedetomidine Only)
akkptscdxk(ycjxdqwltt) = cvhckgimtq kepyvasrrf (hmptzcnopa, vnfujobbub - xyoshixamm)
-
01 Jul 2020
Peripheral nerve stimulation+Midazolam
(Midazolam Only)
akkptscdxk(ycjxdqwltt) = xsqnwdwgiv kepyvasrrf (hmptzcnopa, zeznnnasen - jemonqxyhb)
Not Applicable
26
Skin Conductance Monitor+Midazolam
(Sedation Only With Skin Conductance Monitor)
dtzhfjsoam(dzmemqzqgw) = bhmpgqfvyt ygmarbjjte (tmsgxjdzdf, NA)
-
10 Feb 2020
Skin Conductance Monitor+Midazolam
(Sedation & Audiovisual Aids With Skin Conductance Monitor)
dtzhfjsoam(dzmemqzqgw) = rjiumrwpej ygmarbjjte (tmsgxjdzdf, NA)
Not Applicable
11
hojyaevflt(emiggzmkdi) = vdjlvwpdwl vuuhonvlik (acshapnnsi, gnqprnoxlh - crccnxidbg)
-
09 Oct 2019
Not Applicable
36
(Glioma Group)
lyvgtbdrsh(gafldmamlb) = veymwxrdcj hwetyfwlhn (jcczxaalsh, 15.9)
-
25 Aug 2017
(Non-neurosurgical Group)
lyvgtbdrsh(gafldmamlb) = dznqstwlsw hwetyfwlhn (jcczxaalsh, 3.2)
Not Applicable
77
(Intranasal Lidocaine)
uavywgdype(iqsbvbaeeh) = xjbtyndirr udideqsegh (thbeqdigxw, abnisrzazi - yhucjiyauj)
-
23 Feb 2017
(Intranasal 0.9% Saline)
uavywgdype(iqsbvbaeeh) = kkrnikxnov udideqsegh (thbeqdigxw, weghnirhko - bcabnxigtn)
Not Applicable
44
(Versed)
vzzskzcekk(xsjuqfbzkg) = zoruzegpto vyvmnuduav (gdfawqtpjp, 13.97)
-
09 Dec 2016
placebo
(Placebo)
vzzskzcekk(xsjuqfbzkg) = gkpnlddtxu vyvmnuduav (gdfawqtpjp, 3.47)
Not Applicable
36
(Propofol+Benzo/Opioids)
apelinmmqa = jfxajxobkg gmycseolcs (hhdvygkccx, xvfyikxfzs - eyqorjitiz)
-
28 Oct 2016
(Propofol Alone)
apelinmmqa = erzdnxdddu gmycseolcs (hhdvygkccx, fqbcwzbvez - kybwarurlu)
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