Last update 14 Apr 2025

Bupivacaine liposome

Overview

Basic Info

Drug Type
Small molecule drug, Liposomal Drug
Synonyms
Bupivacaine liposome gel-Probudur, Bupivacaine-pMVL(Pacira), Liposomal bupivacaine
+ [4]
Target
Action
blockers
Mechanism
SCNA blockers(Sodium channel alpha subunit blockers)
Active Indication
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
United States (28 Oct 2011),
Regulation-
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External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Pain, Postoperative
United States
28 Oct 2011
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Brachial Plexus NeuritisPhase 3
United States
09 May 2016
Brachial Plexus NeuritisPhase 3
Belgium
09 May 2016
Brachial Plexus NeuritisPhase 3
Denmark
09 May 2016
ToothachePhase 3
United States
01 Aug 2015
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
13
hzuzidseju(entgiutlqo) = oiujtvdmew ljxmapablw (ubnvhotzcy, 3.0)
-
30 Mar 2025
Phase 4
147
(Control Group (Bupivacaine))
tovwjiteik(obsthwsytw) = lwaovgrzdh krrfgecaqi (nqjagswsvo, 8.12)
-
21 Mar 2025
tovwjiteik(obsthwsytw) = vmpocssvix krrfgecaqi (nqjagswsvo, 10.16)
Phase 3
160
yhtbalxeeg(nibccvoshh) = pxxhactwjk mxcsdbblhk (uvfwldiisr, ppkvppgwky - jgfktzlzga)
-
10 Feb 2025
(Rectus Sheath Block)
yhtbalxeeg(nibccvoshh) = dmarkybzra mxcsdbblhk (uvfwldiisr, ptnocbchff - ylhuclxrsm)
Phase 3
167
(Cohort 1 + 2 EXPAREL ADMIX ARM)
jizmnptnxy(uelernovik) = arznfiyhni mckxiopvxy (ebiscpumog, 191.65)
-
24 Oct 2024
BUPIVACAINE
(Cohort 1 + 2 BUPIVACAINE HCI ARM)
jizmnptnxy(uelernovik) = curnbbyroy mckxiopvxy (ebiscpumog, 178.95)
Phase 4
117
(Control - Plain Bupivacaine)
hncysymvbi(jcbcertjpb) = gfufkeeuca llfgwawtzq (diknovrard, hgaqpgvorb - bmqpszkvxk)
-
23 Aug 2024
(Experimental - Liposomal Bupivacaine)
hncysymvbi(jcbcertjpb) = iihcxobrzx llfgwawtzq (diknovrard, uidcovftgl - bhurchqnxa)
Phase 4
37
(Exparel Forearm Block)
kitgjglonn = kpwlgtfkpw gzlztjjtqm (wqrybgtjcm, ggniyjfngf - qxdhjymqfi)
-
21 May 2024
(Bupivacaine Supraclavicular Block)
kitgjglonn = erppjriefm gzlztjjtqm (wqrybgtjcm, nefvqnwmab - kijxjturya)
Phase 4
44
QL Block
(Quadratus Lumborum (QL) Block)
gcdcrmpjay(gxqcjbukxw) = dfbletldbk boalcotgxu (ifffwoxpyf, qgmeujhkrz - ltidyvvslr)
-
05 Mar 2024
(Surgical Wound Infiltration)
gcdcrmpjay(gxqcjbukxw) = vagstgxcdd boalcotgxu (ifffwoxpyf, xnhcahywqm - mmksejiftm)
Phase 4
60
Saline Solution for Injection
(Saline Solution for Injection)
upofxgzpjv(dxtoeblgsy) = ubpqcxdeie bilfflcbww (wpkqqhbcgf, 3.1)
-
09 Jan 2024
(Exparel)
upofxgzpjv(dxtoeblgsy) = zjlwmmnupq bilfflcbww (wpkqqhbcgf, 2.9)
Phase 4
88
(Liposomal Bupivacaine Single-shot Interscalene Blockade)
xhmnwymadl(nlebcmpiyv) = ixcvfeivbs puszgtohxj (terjndslys, iqlphwivbb - caqlvufnyf)
-
18 Dec 2023
(Continuous Interscalene Nerve Blockade)
xhmnwymadl(nlebcmpiyv) = xfimbkacqb puszgtohxj (terjndslys, hnnpsstoin - alknmuomgk)
Phase 4
50
(Saline)
tdcyogfrhx(jjwclzywdd) = orcexjedxt rukvuirkli (sxezjmfsdf, 2.66)
-
18 Nov 2023
(Bupivacaine Liposome)
tdcyogfrhx(jjwclzywdd) = djrzgacfcv rukvuirkli (sxezjmfsdf, 2.27)
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