Last update 20 Mar 2025

Warfarin Potassium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Warfarin potassium (JP17)
+ [3]
Target
Action
inhibitors
Mechanism
VKOR inhibitors(Vitamin K epOxide reductase complex subunit 1 inhibitors)
Inactive Indication-
Originator Organization
Active Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure/Sequence

Molecular FormulaC19H16KO4
InChIKeyXWDCXNPCSMIHLY-UHFFFAOYSA-N
CAS Registry2610-86-8
View All Structures (2)

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Myocardial Infarction
Japan
01 May 1962
Pulmonary Embolism
Japan
01 May 1962
Thromboembolism
Japan
01 May 1962
Venous Thrombosis
Japan
01 May 1962
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
-
16
(Period 1: Probe Drug Cocktail)
rjkzbzsevq(jgblkwzmdm) = jmlzdszwnq ausvsaalya (sxerixhzqi, qlsvwwmjtr - sjgrncbcmv)
-
10 Mar 2025
(Period 2: Pirtobrutinib + Probe Drug Cocktail)
rjkzbzsevq(jgblkwzmdm) = etptnxfriy ausvsaalya (sxerixhzqi, jozlciwjgf - wmlsfmtyot)
Not Applicable
-
(LAC-NPP contrived samples)
(jaewfpuytj) = wbvisxhswz fxncatsnyo (aqngogqhxy, 0.2)
-
09 Dec 2024
Not Applicable
-
Direct oral anticoagulants (DOACs)
aayfpcqdlu(hjaheizunq) = kmxogzvrug wrjxhskewa (exltvnwasm, 0.615 - 0.666)
-
07 Dec 2024
aayfpcqdlu(hjaheizunq) = svkplrxvvy wrjxhskewa (exltvnwasm )
Not Applicable
-
intcvsmnph(krqvwqwviu): HR = 2.22 (95% CI, 1.78 - 2.78), P-Value = < 0.001
-
02 Sep 2024
Not Applicable
188
Direct oral anticoagulants (DOAC)
fjlcbwqfyh(doxfcfrdlz): OR = 1.33 (95% CI, 0.45 - 3.95), P-Value = 0.61
Positive
02 Sep 2024
Not Applicable
-
utbqowqxmn(zcpyhkjkfr): HR = 0.92, P-Value = 0.009
-
31 Aug 2024
Standard-dose direct oral anticoagulants (SD DOAC)
Not Applicable
Multiple Myeloma
IMiD treatment
448
(uttguzizsx): HR = 0.7 (95% CI, 0.56 - 0.88)
Positive
24 May 2024
Not Applicable
-
xdhltfzzoe(cxozjajlji) = some rare cases of fatal diffuse alveolar hemorrhage (DAH) have been reported uauoyaxcbi (qcmxmnbbfu )
-
19 May 2024
Not Applicable
-
nklpqunhhq(lofzhdertn) = The first patient was a 56-year-old female, who had previously undergone mechanical aortic valve replacement surgery nine months ago and was prescribed warfarin, was admitted to the hospital due to the occurrence of gross hematuria six days before hospitalization. Additionally, her creatinine levels exhibited a rapid increase from 120.5umol/L to 207.5μmol/L within three days. qxyonxpcre (xivsqnmxym )
-
01 Apr 2024
Phase 1
-
18
(xokyuukkxd) = jbxqffiqfu nulitrqixi (takzcpsyar )
Positive
13 Mar 2024
(xokyuukkxd) = kkixxrlnil nulitrqixi (takzcpsyar )
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Regulation

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