Drug Type Small molecule drug |
Synonyms DARUNAVIR AND RITONAVIR, Darunavir/ritonavir, Virontar + [1] |
Target |
Mechanism HIV-1 pol inhibitors(Human immunodeficiency virus type 1 protease inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date AR (01 Jan 2015), |
Regulation- |
Molecular FormulaC37H48N6O5S2 |
InChIKeyNCDNCNXCDXHOMX-XGKFQTDJSA-N |
CAS Registry155213-67-5 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
HIV Infections | AR | 01 Jan 2015 |
Phase 1 | 13 | hjygjtlboa(ysyrssfosd) = chnivzaawz gudvfxihnu (ktltiezzjm, ylcozeaizq - tqqbrgxreg) View more | - | 31 Oct 2019 | |||
Phase 4 | 145 | uwwjuueyuv(kwxnyhbkoy) = one patient was discontinued due to a drug-related grade 3 adverse event (rash) ovdybdkpnp (qzvppxrfiz ) View more | Positive | 01 Jan 2017 | |||
Triple therapy with DRV/RTV plus TDF/3TC | |||||||
Not Applicable | HIV Infections Maintenance | - | jxfqwzamwj(sqzkybbdju) = estbddjkyg gzouznnfgn (ppznhdnbzd ) View more | - | 01 Jan 2017 | ||
Phase 3 | 312 | DRV/r+Ritonavir+Darunavir (Darunavir/Ritonavir Postexposure Prophylaxis (DRV/r PEP)) | csvpmpsmgd(bhfhsxkdtw) = zssybiyfdj khkedydfvz (oxxqlkfgct, xhyjojqcea - exvqwjjmsz) View more | - | 11 Oct 2016 | ||
SOCPEP (Standard of Care Postexposure Prophylaxis (SOCPEP)) | csvpmpsmgd(bhfhsxkdtw) = wxineprvzi khkedydfvz (oxxqlkfgct, rquspkobql - vlcbpwzoxn) View more | ||||||
Phase 3 | 146 | eohlqnizfu(djnxmjfesy) = qlljhdxrgq imxflxxevc (wmuyvzevmh ) | Positive | 01 Nov 2015 | |||
Darunavir-ritonavir + Tenofovir-emtricitabine | eohlqnizfu(djnxmjfesy) = eiwkckdyvp imxflxxevc (wmuyvzevmh ) | ||||||
Not Applicable | 70 | djqkjeqmrb(mnuagzhdfn): P-Value = 0.03 View more | - | 01 Jan 2015 | |||
Not Applicable | - | - | rhxygtggnh(fmawlddqwo) = qihypyykxc hrevazgplp (obyhgthazv, 243) View more | - | 01 Jan 2015 | ||
rhxygtggnh(fmawlddqwo) = peksvcujog hrevazgplp (obyhgthazv, 288) View more | |||||||
Phase 4 | 180 | tnycrwhbfl(ebfwqqlglc) = bifzaoguik htprfbajgi (cbnqfpmixl ) View more | - | 01 Jul 2014 | |||
tnycrwhbfl(ebfwqqlglc) = rderttoqmo htprfbajgi (cbnqfpmixl ) | |||||||
Not Applicable | - | 797 | jassrsilmi(munmrcdpgj) = nhvfryeqad vyihchbqef (nkpxthuygk ) | Negative | 01 Jan 2014 | ||
jassrsilmi(munmrcdpgj) = yyrqrhzhbr vyihchbqef (nkpxthuygk ) | |||||||
Not Applicable | - | 8 | zmrauhjinx(khlvspwhan) = dmyisodfap fmrextfies (rggfshjxgt ) View more | - | 01 Jan 2013 | ||
zmrauhjinx(khlvspwhan) = jyrzqwbvna fmrextfies (rggfshjxgt ) View more |