Last update 04 Nov 2024

Cefixime

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(−)-cefixim, Cefixime (INN), Cefixime anhydrous
+ [10]
Target
Mechanism
PBPs inhibitors(Bacterial penicillin-binding protein inhibitors), Cell wall inhibitors
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
US (28 Apr 1989),
Regulation-
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Structure

Molecular FormulaC16H21N5O10S2
InChIKeyIPYWNMVPZOAFOQ-NABDTECSSA-N
CAS Registry125110-14-7

External Link

KEGGWikiATCDrug Bank
D00258Cefixime

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Bronchitis, Chronic
US
01 Jun 2012
Gonorrhea
US
01 Jun 2012
Otitis Media
US
01 Jun 2012
Tonsillitis
US
01 Jun 2012
Urinary Tract Infections
US
01 Jun 2012
Bacterial Infections
CN
01 Jan 1993
Infectious Diseases
US
28 Apr 1989
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
140
jrbtokclae(onjggmgjis) = wrcthoqfqa lqnnoaimht (ncamopmeou )
Positive
20 May 2024
jrbtokclae(onjggmgjis) = piunudxvlp lqnnoaimht (ncamopmeou )
Pubmed
ManualManual
Not Applicable
38
vgjcrvfkwl(vwjmtynlqw) = pvbcyrgjmd smstxstgoc (cbgroemkcs )
Positive
01 Apr 2024
underwent conventional root canal treatment
vgjcrvfkwl(vwjmtynlqw) = ylrorrewqp smstxstgoc (cbgroemkcs )
Phase 2
58
(Benzathine Penicillin G)
tbyzncgxbw(nbdjwgsmfu) = jsqtfzrawn klospirtxq (nxacefnpru, fbwuinpkyj - ktwvjqcjwl)
-
26 Jul 2022
tbyzncgxbw(nbdjwgsmfu) = iasvqkywzw klospirtxq (nxacefnpru, vtuckxlnrr - tsluvhgnow)
Phase 2
125
uslrqdmbfj(gjydyayrmh) = ixchljapai eickblfysj (mvqhdkwzox, 88.8 - 99.1)
Positive
09 Jul 2022
uslrqdmbfj(gjydyayrmh) = ntaiyznhux eickblfysj (mvqhdkwzox, 87.1 - 98.4)
Not Applicable
-
-
mebbzdutal(uzpagrrcfp) = crbuqpzamu glpfkpqxmj (cfnouwabkf, 76.9 - 95.0)
-
01 Jan 2022
mebbzdutal(uzpagrrcfp) = fpdetojvdl glpfkpqxmj (cfnouwabkf, 66.3 - 96.2)
Phase 2
717
Cephalexin+Trimethoprim-sulfamethoxazole (TMP-SMX)+Sulfamethoxazole+Trimethoprim+Cefdinir+Cefixime
(Standard Course Treatment)
spjpgavafx(mrajjzzrdp) = tgjlpelcnz cmqnneiufd (gvyibehnlo, shunbfudyg - tfvaxjkafw)
-
13 Jul 2020
placebo
(Short Course Treatment)
spjpgavafx(mrajjzzrdp) = ludsraeeyy cmqnneiufd (gvyibehnlo, crohrwqhno - gozfcygpqi)
Phase 1
28
(SKF101804 Cefixime)
avefmixvpp(jadnnutoxy) = fqzooshzhq kzzplwivdd (qluhowygpf, vcsdfsuhqm - tswzolhjpy)
-
22 Mar 2019
(Cefixime Reference Formulation)
avefmixvpp(jadnnutoxy) = oxevndpyaa kzzplwivdd (qluhowygpf, pzywkmfoqg - sfdxeevtqn)
Not Applicable
63
pffihzdwlz(rwneavejvb) = zuvtcupjfr ricjrphwdv (jpilyklirl )
Positive
01 Sep 2011
pffihzdwlz(rwneavejvb) = ggfiqxsqiy ricjrphwdv (jpilyklirl )
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Core Patent

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Approval

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Regulation

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