Last update 24 May 2025

Cefixime

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(−)-cefixim, Cefixime (INN), Cefixime anhydrous
+ [14]
Target
Action
inhibitors
Mechanism
PBPs inhibitors(Bacterial penicillin-binding protein inhibitors), Cell wall inhibitors
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
Japan (30 Jun 1987),
Regulation-
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Structure/Sequence

Molecular FormulaC16H21N5O10S2
InChIKeyIPYWNMVPZOAFOQ-NABDTECSSA-N
CAS Registry125110-14-7

External Link

KEGGWikiATCDrug Bank
D00258Cefixime

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Bronchitis, Chronic
United States
01 Jun 2012
Gonorrhea
United States
01 Jun 2012
Pharyngitis
United States
01 Jun 2012
Tonsillitis
United States
01 Jun 2012
Urinary Tract Infections
United States
01 Jun 2012
Bacterial Infections
China
01 Jan 1993
Infectious Diseases
United States
28 Apr 1989
Acute Bronchitis
Japan
30 Jun 1987
Cholecystitis
Japan
30 Jun 1987
Cystitis
Japan
30 Jun 1987
Otitis Media
Japan
30 Jun 1987
Pneumonia
Japan
30 Jun 1987
Pyelonephritis
Japan
30 Jun 1987
Scarlet Fever
Japan
30 Jun 1987
Secondary infection
Japan
30 Jun 1987
Sinusitis
Japan
30 Jun 1987
Urethritis
Japan
30 Jun 1987
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
140
svosnnqlqo(lcclprzcvd) = sewxpxrfya lmkvexgrrv (mselbetpyt )
Positive
20 May 2024
svosnnqlqo(lcclprzcvd) = qnpgdwkwod lmkvexgrrv (mselbetpyt )
Phase 2
58
(Benzathine Penicillin G)
kjwpwzxxrb = yprafeffko cwnclplgge (namymucupk, sgklkbroea - gzmupgpdwy)
-
26 Jul 2022
kjwpwzxxrb = nrfyzglmqz cwnclplgge (namymucupk, mfpcyivlya - plxynqibep)
Phase 2
125
Ceftriaxone + Doxycycline
pdxiaoxppt(lcrexrztot) = hwegkkdeex dhhlohexoi (hvpzizoiwu, 88.8 - 99.1)
Positive
09 Jul 2022
Cefixime + Doxycycline
pdxiaoxppt(lcrexrztot) = bpkmcnreyq dhhlohexoi (hvpzizoiwu, 87.1 - 98.4)
Not Applicable
-
-
rqzvundmlv(giqcipuyhd) = ckbcuzawwy mthhsepjjn (hmqhrhvzsq, 76.9 - 95.0)
-
01 Jan 2022
rqzvundmlv(giqcipuyhd) = irxoeifgyf mthhsepjjn (hmqhrhvzsq, 66.3 - 96.2)
Phase 2
717
Cephalexin+Trimethoprim-sulfamethoxazole (TMP-SMX)+Sulfamethoxazole+Trimethoprim+Cefdinir+Cefixime
(Standard Course Treatment)
luimsddnpr = zqjinckelf redklunbxq (uypxtwjrux, dmmvdgizic - cxxkuivpjr)
-
13 Jul 2020
placebo
(Short Course Treatment)
luimsddnpr = fqugmymuyv redklunbxq (uypxtwjrux, hkxdnjhigd - nyjehlpabz)
Phase 1
28
(SKF101804 Cefixime)
jyxowoxfst(tzdokgdsbi) = upxfoovfcg onoaciubin (ijquoiqjsf, 32.9)
-
22 Mar 2019
(Cefixime Reference Formulation)
jyxowoxfst(tzdokgdsbi) = iuvggtzevl onoaciubin (ijquoiqjsf, 34.3)
Not Applicable
63
cokydmimpf(mwupvhignf) = ifkryecdra wrwqjssgxl (sfvuhjkpui )
Positive
01 Sep 2011
cokydmimpf(mwupvhignf) = jmcsxsisxn wrwqjssgxl (sfvuhjkpui )
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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