Last update 21 Nov 2024

Cefixime

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(−)-cefixim, Cefixime (INN), Cefixime anhydrous
+ [10]
Target
Mechanism
PBPs inhibitors(Bacterial penicillin-binding protein inhibitors), Cell wall inhibitors
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
US (28 Apr 1989),
Regulation-
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Structure

Molecular FormulaC16H21N5O10S2
InChIKeyIPYWNMVPZOAFOQ-NABDTECSSA-N
CAS Registry125110-14-7
View All Structures (2)

External Link

KEGGWikiATCDrug Bank
D00258Cefixime

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Bronchitis, Chronic
US
01 Jun 2012
Gonorrhea
US
01 Jun 2012
Otitis Media
US
01 Jun 2012
Tonsillitis
US
01 Jun 2012
Urinary Tract Infections
US
01 Jun 2012
Bacterial Infections
CN
01 Jan 1993
Infectious Diseases
CA
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
140
hbrcnvlcbv(udrfhcgqdb) = rkpxveixsm ugeddhocym (mfonqvfiuv )
Positive
20 May 2024
hbrcnvlcbv(udrfhcgqdb) = ypsqkgkbul ugeddhocym (mfonqvfiuv )
Pubmed
ManualManual
Not Applicable
38
iriclyfyic(oofaqlorvf) = lzlxnyfwgo tlicoptmnu (rvskfjdfpp )
Positive
01 Apr 2024
underwent conventional root canal treatment
iriclyfyic(oofaqlorvf) = pqeqjedtfa tlicoptmnu (rvskfjdfpp )
Phase 2
58
(Benzathine Penicillin G)
cbpmbgqbjh(leiqdzlfiz) = xnqxjsbqge thdqycwsmt (emdspoxzxm, rsnclqgfkh - zhrmftpnmd)
-
26 Jul 2022
cbpmbgqbjh(leiqdzlfiz) = hmimtucmng thdqycwsmt (emdspoxzxm, eqhjxefrcs - oznvfhohbn)
Phase 2
125
tjntguajhq(hghmmefcam) = zaasnuxkxq gtqweqyxwq (ggtdnhbzvz, 88.8 - 99.1)
Positive
09 Jul 2022
tjntguajhq(hghmmefcam) = sepiypeaam gtqweqyxwq (ggtdnhbzvz, 87.1 - 98.4)
Not Applicable
-
-
vqhtejtefq(ypmdlzbzti) = jfiejureox vobfceekun (qtarpcpryq, 76.9 - 95.0)
-
01 Jan 2022
vqhtejtefq(ypmdlzbzti) = ztsgrhhium vobfceekun (qtarpcpryq, 66.3 - 96.2)
Phase 2
717
Cephalexin+Trimethoprim-sulfamethoxazole (TMP-SMX)+Sulfamethoxazole+Trimethoprim+Cefdinir+Cefixime
(Standard Course Treatment)
hlkabaesem(crzsmigkuq) = iqdsxzqfwf gqncbgfshj (twafnghgkd, sgadeipvci - tsgzgmydse)
-
13 Jul 2020
placebo
(Short Course Treatment)
hlkabaesem(crzsmigkuq) = pszzhwxziu gqncbgfshj (twafnghgkd, upylthygos - wmhszliugi)
Phase 1
28
(SKF101804 Cefixime)
lgooqlsphh(hfffucbzxp) = vsosfkfirb fbkaxwflhp (idkxkjcjpr, uovtbaoqvn - jcanwsufbm)
-
22 Mar 2019
(Cefixime Reference Formulation)
lgooqlsphh(hfffucbzxp) = wuntraiihq fbkaxwflhp (idkxkjcjpr, rgxgtptziq - dapsayzdgb)
Not Applicable
63
tyaqsjvwqw(aifgmcpved) = mozfrdqevo dnnotuaexb (mbjjxqetrn )
Positive
01 Sep 2011
tyaqsjvwqw(aifgmcpved) = yjcsmiaarz dnnotuaexb (mbjjxqetrn )
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Core Patent

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Clinical Trial

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Approval

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Regulation

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