Drug Type Small molecule drug |
Synonyms Artesunate/pyronaridine, PANDA, Pyramax + [3] |
Target |
Action inhibitors |
Mechanism ATP2A1 inhibitors(Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 inhibitors), SERCA2 inhibitors(Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date South Korea (17 Aug 2011), |
RegulationOrphan Drug (United States) |
Molecular FormulaC29H35ClN5O6P |
InChIKeyAFQUPAGSIINWCQ-UHFFFAOYSA-N |
CAS Registry76748-86-2 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Malaria | South Korea | 17 Aug 2011 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Malaria, Vivax | Phase 3 | Cambodia | 01 Mar 2007 | |
Malaria, Vivax | Phase 3 | India | 01 Mar 2007 | |
Malaria, Vivax | Phase 3 | Indonesia | 01 Mar 2007 | |
Malaria, Vivax | Phase 3 | Thailand | 01 Mar 2007 | |
Malaria, Falciparum | Phase 3 | United States | 01 Jan 2007 | |
Malaria, Falciparum | Phase 3 | Burkina Faso | 01 Jan 2007 | |
Malaria, Falciparum | Phase 3 | Cambodia | 01 Jan 2007 | |
Malaria, Falciparum | Phase 3 | Côte d'Ivoire | 01 Jan 2007 | |
Malaria, Falciparum | Phase 3 | Gambia | 01 Jan 2007 | |
Malaria, Falciparum | Phase 3 | Ghana | 01 Jan 2007 |
Phase 3 | - | - | nyxcruvviz(aopxcuqhqk) = klgbaapkye vbkekiyprn (meuvqnvsfi ) View more | Positive | 21 Feb 2025 | ||
ISTp-uRDT-PA | nyxcruvviz(aopxcuqhqk) = srriljeqwv vbkekiyprn (meuvqnvsfi ) View more | ||||||
Phase 1 | 56 | scwpcibkoc = cpctoepnol wbxltlzwbu (pratccuiql, uyhenqxkqb - tsighqwkmd) View more | - | 14 Dec 2023 | |||
Phase 1 | 34 | uitdqlnxjv(rekhstmspu) = fzyyeipjuv jbjxmotmnm (iczbtxolmq, 223.2) View more | - | 03 Feb 2023 | |||
(Arm B Pyramax) | uitdqlnxjv(rekhstmspu) = gjzkvujkmz jbjxmotmnm (iczbtxolmq, 69.6) View more | ||||||
Phase 3 | 30 | (Pyronaridine - Artesunate) | drxcueqbbj = mvdhgvzcju irvnpyalky (vtlqmmxnic, gmejcjgoqo - wwiqmuxser) View more | - | 26 Jan 2022 | ||
Chloroquine (Chloroquine) | drxcueqbbj = mwuziedaof irvnpyalky (vtlqmmxnic, wugpptxope - jmqwozrkyj) View more | ||||||
Phase 3 | 535 | (PA Group) | uoxycfchif = turxnpjusj dmnzyidlvk (mchmmntvir, nbfdyovond - bnbkhbjalp) View more | - | 22 Nov 2021 | ||
arthemeter lumefantrine (AL Group) | uoxycfchif = hmhptwodju dmnzyidlvk (mchmmntvir, jaghntwavk - sfsaikbbhq) View more | ||||||
Phase 2 | 60 | (Group A (Tablets)) | eziwlmkchz = ltinjzddnv smrqajimni (mzmcjduoss, crsqwdnauf - azkgeutnus) View more | - | 22 Nov 2021 | ||
(Group B (Tablets)) | eziwlmkchz = kyhyzpjpzf smrqajimni (mzmcjduoss, xtiemoaurl - yqxkrvhfip) View more | ||||||
Phase 4 | - | iqlnytjvge(jptyykvxcb) = kxtiyuzdjr nluyufbpwu (lakqizpyfm ) View more | - | 17 Nov 2021 | |||
Phase 3 | 456 | (Pyronaridine Artesunate) | ozbdhmidle = qxnkfaatfh jrtnrtpgyc (yhjhwvylpl, pgbsuaepya - ptgffeyafw) View more | - | 20 Sep 2021 | ||
Chloroquine (Chloroquine) | ozbdhmidle = nnhstjhszo jrtnrtpgyc (yhjhwvylpl, gwdqycqasg - tfhuydwfyt) View more | ||||||
Phase 3 | 1,272 | (PA Group) | ccgkeiiuzs = ildrwbssom wgoedbvzau (oewhuglhoy, mdbwnlljsl - zcgeybkaxk) View more | - | 20 Sep 2021 | ||
(AL Group) | ccgkeiiuzs = azqvyucdft wgoedbvzau (oewhuglhoy, sqmwrjhfgl - eeobcshfmp) View more | ||||||
Phase 3 | 1,271 | (Pyronaridine - Artesunate) | hphnixnuyc = gdttwfqhhr tpmriqvfhd (tkkgtcsono, hplthrlhuq - ffnecvbshg) View more | - | 17 Sep 2021 | ||
(Mefloquine Plus Artesunate) | hphnixnuyc = lopnsmovmb tpmriqvfhd (tkkgtcsono, ogtbmvregp - wqcreybqxu) View more |