Drug Type Small molecule drug |
Synonyms Artesunate/pyronaridine, PANDA, Pyramax + [3] |
Target |
Mechanism ATP2A1 inhibitors(Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 inhibitors), SERCA2 inhibitors(Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date KR (17 Aug 2011), |
RegulationOrphan Drug (US) |
Molecular FormulaC19H28O8 |
InChIKeyFIHJKUPKCHIPAT-AHIGJZGOSA-N |
CAS Registry88495-63-0 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Malaria | KR | 17 Aug 2011 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Malaria, Falciparum | Phase 1 | KH | 01 Jan 2007 | |
Malaria, Falciparum | Phase 1 | MZ | 01 Jan 2007 | |
Malaria, Falciparum | Phase 1 | VN | 01 Jan 2007 | |
Malaria, Falciparum | Phase 1 | ID | 01 Jan 2007 | |
Malaria, Falciparum | Phase 1 | BF | 01 Jan 2007 | |
Malaria, Falciparum | Phase 1 | TZ | 01 Jan 2007 | |
Malaria, Falciparum | Phase 1 | SN | 01 Jan 2007 | |
Malaria, Falciparum | Phase 1 | IN | 01 Jan 2007 | |
Malaria, Falciparum | Phase 1 | ML | 01 Jan 2007 | |
Malaria, Falciparum | Phase 1 | GH | 01 Jan 2007 |
Phase 1 | 56 | uaultzrgbo(qhpxqwcnil) = lxelpzexxw bkgjakkazg (zhkaaeybko, oucnfvbkal - zrxkljmukf) View more | - | 14 Dec 2023 | |||
Phase 1 | 34 | qofpzkeknm(sipdavwdks) = tbdefmdthc vszdooxwkk (foymzmhjxn, msvkwsypsm - rngyaqldis) View more | - | 03 Feb 2023 | |||
(Arm B Pyramax) | qofpzkeknm(sipdavwdks) = znckaxwhvs vszdooxwkk (foymzmhjxn, cketnbgedf - nyridhpyfg) View more | ||||||
Phase 3 | 30 | (Pyronaridine - Artesunate) | wgdmpnnrbz(vmnbsgsnok) = qwccbqlueb pmlhywpnef (kvwfoafscz, lehabtyjjp - jaxrcwvnyg) View more | - | 26 Jan 2022 | ||
(Chloroquine) | wgdmpnnrbz(vmnbsgsnok) = jxbthgpugo pmlhywpnef (kvwfoafscz, xbasarqmzu - rmmdbmgvnr) View more | ||||||
Phase 3 | 535 | (PA Group) | doqxhepfni(rlmbheuamj) = lvuztqabss jnfnddxnjo (hwzbntstoh, nljvwxesxl - uzsltvkbtc) View more | - | 22 Nov 2021 | ||
arthemeter lumefantrine (AL Group) | doqxhepfni(rlmbheuamj) = ulofbgqydf jnfnddxnjo (hwzbntstoh, eosvjvegom - ewczecqxev) View more | ||||||
Phase 2 | 60 | (Group A (Tablets)) | emppwmrcsj(dclswctvhn) = rlabnjlhoc kgqppsoodq (hkaajtmzhu, ixyhprnurm - vncbpmcmfl) View more | - | 22 Nov 2021 | ||
(Group B (Tablets)) | emppwmrcsj(dclswctvhn) = atfldibkbk kgqppsoodq (hkaajtmzhu, xeveprqwtz - aoobabebwl) View more | ||||||
Phase 3 | 456 | (Pyronaridine Artesunate) | pwbupcvlqs(yfgczjibit) = viwrifnhrg bqfsduvsbp (mcyyyhcwhu, qsgdkglcdx - cyuqapapay) View more | - | 20 Sep 2021 | ||
(Chloroquine) | pwbupcvlqs(yfgczjibit) = blbsrimrsw bqfsduvsbp (mcyyyhcwhu, evwhfqdecn - gigkipzqcd) View more | ||||||
Phase 3 | 1,272 | (PA Group) | eemiwgeydn(ndmmqxildp) = bnczhobsox ssmdhzbumo (irdkxexfpd, pvkkjahigf - bhdgaieeay) View more | - | 20 Sep 2021 | ||
Coartem® (artemether lumefantrine) (AL Group) | eemiwgeydn(ndmmqxildp) = dadzxkduyf ssmdhzbumo (irdkxexfpd, amxkgwgzod - vilpkvsatx) View more | ||||||
Phase 3 | 1,271 | (Pyronaridine - Artesunate) | zzmvhdtqyv(ariwzjgyvh) = pshnniqomh hsjaqedgye (yqvenagrhu, jjcbqzpptk - sqgjmilljl) View more | - | 17 Sep 2021 | ||
(Mefloquine Plus Artesunate) | zzmvhdtqyv(ariwzjgyvh) = zoyxfbqbeb hsjaqedgye (yqvenagrhu, chutaltmjg - brkzfnuzxb) View more | ||||||
Not Applicable | - | (fxgvlufuhd) = observed at Day 7, resolving by Day 28 fmwgnjmkbm (htwfsunivs ) View more | - | 06 May 2020 | |||
Phase 3 | 197 | dlrnjdkhaj(edeainmpyg) = maaifcvlvs lkeedcsdmy (begokfbabl ) View more | - | 04 Jun 2018 | |||
dlrnjdkhaj(edeainmpyg) = aigqbbyqol lkeedcsdmy (begokfbabl ) View more |