Last update 04 Nov 2024

Haloperidol

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
HAL, Haloperidol (JP17/USP/INN), HPD
+ [8]
Target
Mechanism
DRDs agonists(Dopamine receptors agonists)
Inactive Indication
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure

Molecular FormulaC21H23ClFNO2
InChIKeyLNEPOXFFQSENCJ-UHFFFAOYSA-N
CAS Registry52-86-8

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Psychotic Disorders
US
12 Apr 1967
Tourette Syndrome
US
12 Apr 1967
Bipolar Disorder
JP
24 Oct 1964
Schizophrenia
JP
24 Oct 1964
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
9,132
tvyvkgwzak(gtjfymzynt): RR = 3.38 (95% CI, 2.28 - 5.02)
-
03 Jul 2024
Olanzapine (oral)
Phase 4
1,000
uhtncbbsno(kkrevdnuck): Difference (Mean) = 0.04 (95% CI, - 0.03 - 0.11), P-Value = 0.091
Positive
01 Jan 2024
Placebo
Phase 3
132
svadjurizw(vzqsnvxtya): RR = 0.98 (95% CI, 0.73 - 1.31), P-Value = 0.87
Negative
30 Oct 2023
Placebo
Phase 4
1,000
xcmqoowkle(fwqunbodjx) = Serious adverse reactions occurred in 11 patients in the haloperidol group and in 9 patients in the placebo group. plcdbtdljb (dwutehnntn )
Negative
26 Oct 2022
Placebo
Phase 2/3
70
(Escalation Group)
vhoehkaesn(botkfduysz) = nochtrmmrr zwekcqsdqf (zmzkdganck, pbowobwnxm - mngjmjsmoj)
-
01 Sep 2022
(Rotation Group)
vhoehkaesn(botkfduysz) = bmkjqthrdh zwekcqsdqf (zmzkdganck, ppgojsnvve - njbvczxrrd)
Phase 4
100
(Haloperidol + Promethazine + Chlorpromazine)
pncppoezhl(drkpgvcuyu) = hjtmoimshs putvzdrfnk (aevfhvxfuk, toebgnmonq - furlwaqxxo)
-
14 Jun 2022
(Haloperidol + Promethazine)
pncppoezhl(drkpgvcuyu) = fadesnvnmt putvzdrfnk (aevfhvxfuk, spgrqcdwxs - ctjdrzaahv)
Phase 1
-
32
(Reference Product (Treatment A))
wiwfkjxiih(oshriylpjt) = hhortdctzx zqyuxuoxqm (ailrscvqxc, ihuwjiotyf - lelomoztbg)
-
08 Jun 2022
wiwfkjxiih(oshriylpjt) = othjpnmnnb zqyuxuoxqm (ailrscvqxc, voswjwllrc - hbvpspofes)
Phase 1
-
32
(Reference Product (Treatment A))
hzkvpedzox(gwinzqayel) = ylupgpmgop kiihotawvr (yxddpcujjh, qfceqqevuw - izwczxgrxi)
-
08 Jun 2022
hzkvpedzox(gwinzqayel) = xgdmxhcrck kiihotawvr (yxddpcujjh, ujilcmqnao - ndnoqeguwz)
Phase 4
35
xivnezufzj(pxkgfbtcgf) = srqzxuzcav uuovbkkrry (ibhozzgcfx, elifrmiako - acunkarpeq)
-
01 Mar 2021
Phase 4
33
epiijzeqef(vwmfoxxggw) = ysqicgemtw sxpyonmwnf (cjwxiztsfk )
-
05 Nov 2020
epiijzeqef(vwmfoxxggw) = armtarwdpw sxpyonmwnf (cjwxiztsfk )
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