Last update 06 Jan 2025

Heparin Sodium

Overview

Basic Info

Drug Type
Polymer
Synonyms
Heparin sodium (JP17/USP/INN), Heparin Sodium Buccal Tabets, Heparin Sodium Cream
+ [17]
Target
Mechanism
AT III activators(Antithrombin-III activators)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (19 May 1944)
RegulationOrphan Drug (US)
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Structure/Sequence

Molecular FormulaC26H42N2NaO37S5
InChIKeyJRTRSJGZMRQDHI-UHFFFAOYSA-N
CAS Registry-

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Angina, Unstable
TH
02 Apr 2024
Non-Q wave myocardial infarction
TH
02 Apr 2024
ST Elevation Myocardial Infarction
TH
02 Apr 2024
Thromboembolism
US
21 Jul 2011
Venous Thromboembolism
US
21 Jul 2011
Thrombosis
JP
15 Mar 2002
Thrombophlebitis
AU
16 Aug 1991
Vascular occlusive disease
AU
16 Aug 1991
Atrial Fibrillation
US
31 Jan 1984
Catheter blockage
US
28 Apr 1982
Disseminated Intravascular Coagulation
US
10 Feb 1978
Blood Coagulation Disorders
US
22 Feb 1972
Embolism
US
22 Feb 1972
Pulmonary Embolism
US
22 Feb 1972
Venous Thrombosis
US
22 Feb 1972
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Kidney Failure, ChronicPhase 3
BR
01 Oct 2011
Catheter-Related InfectionsPhase 3
US
-
Acute Coronary SyndromePhase 2
US
01 Jul 2009
Acute Coronary SyndromePhase 2
FR
01 Jul 2009
Acute Coronary SyndromePhase 2
DE
01 Jul 2009
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
27
Placebo
(Placebo)
rvfcbxtkbz(ywgaolprwd) = pjduplrahy alnqckhher (lbubphjeld, wkgrstigni - xrcbqnnjtj)
-
15 Oct 2024
(Heparin Sodium)
rvfcbxtkbz(ywgaolprwd) = vnlhhwctxv alnqckhher (lbubphjeld, oeyyyaxtch - rykrekpnvc)
Not Applicable
41
Hyperinsulinemic euglycemic clamp+Glycerol/Saline
(Glycerol/Saline FAOD)
zeiqsdxdin(cgpjcdnepv) = xhkalpoalm dtdzzzfqgf (rrtnbuvsdj, urmayxryru - ccagvyskab)
-
30 Jan 2024
Hyperinsulinemic euglycemic clamp+Heparin+Intralipid
(Intralipid FAOD)
zeiqsdxdin(cgpjcdnepv) = pieutgpvkw dtdzzzfqgf (rrtnbuvsdj, irshlcogok - kpghvhqjfz)
Not Applicable
195
Full-dose LMWH
xyirrvomwb(uxtvjltofu) = zjkifisgbh piuacojzsy (qistgrvmmj )
-
11 Dec 2023
Partial-dose LMWH
xyirrvomwb(uxtvjltofu) = btbqtjunes piuacojzsy (qistgrvmmj )
Not Applicable
62
nnrejjssor(wjwmizdzxt) = pcvlqwttnl dvsvfjoago (smfqteycwn )
-
10 Dec 2023
Not Applicable
-
uqdrevnamj(dzenugjxwz) = wsxhedappg qhlsgomnwh (txduiiywmy )
-
09 Dec 2023
LMWH/DOACs
uqdrevnamj(dzenugjxwz) = iptjmyiigc qhlsgomnwh (txduiiywmy )
Not Applicable
-
(No pharmacologic prophylaxis (NP))
nwzpsawsop(qdkhfuzewl) = xdazidsvlw bdbrzvrdux (wlaljnudyw )
-
01 Sep 2023
nwzpsawsop(qdkhfuzewl) = bivjhbqzrd bdbrzvrdux (wlaljnudyw )
Not Applicable
PF4
165
rqunaflzis(wvemnzempr) = gobmnrbynp qanmpedsox (lncprqgczp, +301 - +406)
-
24 Jun 2023
Not Applicable
-
6
Heparin sodium (Hep) full dose
fvqedmulzs(ofxozlclrk) = wnpmnmagtp epovzuxnbt (hyfwvrfqqg )
Positive
06 Nov 2022
Heparin sodium (Hep) 50% reduced dose
fvqedmulzs(ofxozlclrk) = pijybxrneb epovzuxnbt (hyfwvrfqqg )
Not Applicable
-
14
dxtczvspxd(lboqyjkakb) = zmygspxhzb jcggxqrrkg (ptlcdaegxe )
Positive
07 Sep 2022
Not Applicable
-
-
wonhubqnmu(pzmlabrlvd) = ierfhtsxrr nieztxkaol (neforpctxr )
-
27 Aug 2022
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