Last update 16 May 2025

Deferoxamine Mesylate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
CanCorda, Cordaneurin, Deferoxamine
+ [17]
Target-
Action
modulators
Mechanism
Fe modulators
Originator Organization
License Organization
Drug Highest PhaseApproved
First Approval Date
United States (01 Apr 1968),
Regulation-
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Structure/Sequence

Molecular FormulaC26H52N6O11S
InChIKeyIDDIJAWJANBQLJ-UHFFFAOYSA-N
CAS Registry138-14-7

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Chronic iron overload
United States
01 Apr 1968
Iron Overload
United States
01 Apr 1968
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Chronic ulcerPhase 2
United States
21 Jul 2020
Skin UlcerPhase 2
United States
21 Jul 2020
Beta-ThalassemiaPhase 2
Greece
01 Jan 2011
Transfusion-dependent Beta ThalassemiaPhase 2
Greece
01 Jan 2011
Anemia, Sickle CellPhase 2
United States
01 May 2003
HemosiderosisPhase 2
United States
01 May 2003
Metastatic Malignant Neoplasm to the LeptomeningesPhase 1
United States
22 Dec 2021
Muscular AtrophyPreclinical
South Korea
20 Jun 2023
Parkinson DiseasePreclinical--04 Jun 2017
Spinal Cord InjuriesPreclinical
European Union
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
Cerebral Hemorrhage
serum hemoglobin | iron | transferrin ...
42
owophdmwdw(girvywnftn) = wppjgvebas zftalhuasn (ldmmbpgwps )
-
01 Feb 2023
Phase 2
22
uyibvltppv(lmloyfkxhb) = sikjdeqqhe yagvoivban (haxwhuflgj, ycacahvjun - ydgjdosxgn)
-
12 Aug 2021
Phase 2
60
qxlgfflell(imayuipruj) = umnyafzqct lwvhdsqdpr (gmskmxjrvp, ocaxnejziz - cwofxrkxuk)
-
24 Jun 2021
Not Applicable
-
ltnkeuxhqj(taadggelfz) = No adverse side effects have been noted with the patient receiving chelation therapy during her hospital admission awyjcanhtt (lrsdxnhjwb )
-
19 Oct 2020
Phase 2
32
pgkksdyqhw = adrrrgaqvp qwpgneegnj (buckmhocyu, mjqjwzpmnh - ehwajefmkv)
-
23 Oct 2019
Phase 2
294
(Deferoxamine Mesylate)
jfeyvvyzaw = ylewtwzkff iyvgufcluo (jsdqogbrhw, hmrtaqjygy - cmxuujoejg)
-
30 May 2019
Placebo (for Deferoxamine Mesylate)
(Normal Saline)
jfeyvvyzaw = dglukaiuav iyvgufcluo (jsdqogbrhw, arrgroxjew - lkpedhaebi)
Phase 2
42
(Deferoxamine)
jgkpenquki = rrvdocivcd jcnjsrgsnp (kmkbigzbod, ybnxaxheub - hkxupgptee)
-
30 May 2019
(Normal Saline)
jgkpenquki = esxxnyddih jcnjsrgsnp (kmkbigzbod, vixlujsvwf - eyojhvxdwf)
Phase 2
291
nsmpmtqovz(iwwdecimhl) = azojlfpuka whpnuwbkks (zbzxmjguem )
Negative
01 May 2019
Placebo
nsmpmtqovz(iwwdecimhl) = zixydtarpz whpnuwbkks (zbzxmjguem )
Phase 4
15
(Inadequate Responders)
ctdvregjaz(pleucvhelb) = dnjbvtwwbv yvtasibsck (pgpofkrnjd, 259.42)
-
06 Feb 2019
(Adequate Responders (Control))
ctdvregjaz(pleucvhelb) = wplalttala yvtasibsck (pgpofkrnjd, 63.4)
Not Applicable
65
pdydfhpxiy(xvqsoxvleo) = ifjfphncfa pnbtindfac (vjelmflduj )
-
30 Aug 2016
No chelation therapy
pdydfhpxiy(xvqsoxvleo) = twsvqfrmfn pnbtindfac (vjelmflduj )
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Core Patent

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Clinical Trial

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Approval

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Regulation

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