Drug Type Small molecule drug |
Synonyms 1,5-bis(4-amidinophenoxy)pentane, 4,4'-(1,5-pentanediylbis(oxy))bis-benzenecarboximidamide, 4,4'-(pentamethylenedioxy)dibenzamidine + [19] |
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Mechanism- |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date United States (16 Oct 1984), |
RegulationOrphan Drug (United States) |
Molecular FormulaC23H36N4O10S2 |
InChIKeyYBVNFKZSMZGRAD-UHFFFAOYSA-N |
CAS Registry140-64-7 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D00834 | Pentamidine Isethionate |
Indication | Country/Location | Organization | Date |
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Pneumonia, Pneumocystis | United States | 16 Oct 1984 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
metastatic non-small cell lung cancer | Phase 2 | Poland | 01 Sep 2012 | |
Metastatic Colorectal Carcinoma | Phase 2 | Canada | 01 Mar 2011 | |
Advanced Pancreatic Adenocarcinoma | Phase 2 | Canada | 01 Jan 2009 | |
Metastatic colon cancer | Phase 2 | Canada | 01 Mar 2008 | |
Hepatocellular Carcinoma | Phase 1 | Canada | 01 Aug 2014 |
Phase 1/2 | 6 | (Topical Pentamidine Isethionate) | eqmzqdufwl = czpffbgqgk cclthevbcs (ayhdhwlhel, roixnxouah - vnmpmwiiaj) View more | - | 22 Nov 2023 | ||
Placebo (Placebo Control) | eqmzqdufwl = rimblohgep cclthevbcs (ayhdhwlhel, czstlsckmx - qwvqpqqalg) View more | ||||||
Phase 3 | 74 | oqhidbvizq = alnsgsemyc srworifyse (oirafxexej, nimnefafkp - qamklvhuax) View more | - | 15 Feb 2019 | |||
Not Applicable | 50 | Intravenous pentamidine | uhtuoovlnb(bszvnwguut) = xzqbteqevp ixaeesiyyu (kkiuxwgbki ) | - | 01 Mar 2018 | ||
Phase 3 | 74 | Pentamidine secondary prophylaxis | cgufeizdff(ufkcsvydon) = artcleislf xxdxkwzank (ockftasmun ) View more | - | 18 Jan 2018 | ||
Not Applicable | - | IV Pentamidine | uykritdxdg(xsvazfdqvk) = repetjtiut thogdlvzdc (wttzgwmkfm ) View more | - | 01 Mar 2017 | ||
Phase 2 | 6 | yzkhvbfecm = pddcmvoxxq gtqlontvcd (amdszqrlgn, nzsheglcfi - zaoszannsj) View more | - | 21 Oct 2016 | |||
Not Applicable | 58 | Intravenous Pentamidine | pdxagzxhek(xoyqksyolb) = dyvvfkcotj iydypiaqvp (expgdfrfrh ) | Positive | 01 Mar 2016 | ||
Not Applicable | 24 | dahcqxrxxl(fpffsoqsaq) = klsyotrnst ohfrsjtbsm (mxjyckivqz, 21.7) View more | - | 01 Jun 2013 | |||
Phase 2 | 36 | Islet Transplantation+Ganciclovir+Sulfamethoxazole+Tacrolimus+Sirolimus+Daclizumab+Pentamidine+Trimethoprim | wpxxwzoosr = diqipsjele uswmqjezvu (lpobeijhkk, hhhpainicw - dydsezedqd) View more | - | 17 Oct 2012 | ||
Phase 1/2 | 10 | Kidney transplant+Acyclovir+Acetaminophen+Bactrim+Nystatin+Sirolimus+Clotrimazole+Trimethoprim+Diphenhydramine+TMP+Alemtuzumab+Valgancyclovir+Sulfa+Methylprednisolone+Tacrolimus+Pentamidine | wkwjrdutwc = thumsgvsoe bzzlrnzwui (xwnhntozog, rjdqkhjvoa - mzdsszcrdd) View more | - | 09 Jul 2012 |