Last update 30 May 2025

Ramipril

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Acuvil, Carasel, Delix
+ [17]
Target
Action
inhibitors
Mechanism
ACE inhibitors(Angiotensin-converting enzyme inhibitors)
Originator Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (28 Jan 1991),
Regulation-
Login to view timeline

Structure/Sequence

Molecular FormulaC23H32N2O5
InChIKeyHDACQVRGBOVJII-JBDAPHQKSA-N
CAS Registry87333-19-5

External Link

KEGGWikiATCDrug Bank
D00421Ramipril

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Cardiovascular Diseases
United States
27 Feb 2007
Myocardial Infarction
United States
27 Feb 2007
Acute myocardial infarction
China
23 Jul 2004
Essential Hypertension
China
23 Jul 2004
Nephrosis
China
23 Jul 2004
Stroke
China
23 Jul 2004
Heart Failure
United States
28 Jan 1991
Hypertension
United States
28 Jan 1991
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Atrial FibrillationPhase 3
France
01 Jul 2008
Atrial FlutterPhase 3
France
01 Jul 2008
Glomerulonephritis, IGAPhase 3
Hong Kong
01 Jul 2004
Angina PectorisPhase 3-01 Jun 2004
Rheumatoid ArthritisPhase 3-01 Jun 2004
Kidney Failure, ChronicPhase 3
Czechia
01 Jan 1998
Kidney Failure, ChronicPhase 3
France
01 Jan 1998
Kidney Failure, ChronicPhase 3
Germany
01 Jan 1998
Kidney Failure, ChronicPhase 3
Hungary
01 Jan 1998
Kidney Failure, ChronicPhase 3
Italy
01 Jan 1998
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
266
vjmwuvqqcj(byztgrercn) = papjarwsqc qomdbuetlq (huslfxnrtj, okuhrczmtz - heasitnxms)
-
24 Apr 2025
Phase 2
75
dbgsxdwyyo(ktlqrilxtw) = vsxocfwicd zzkieyaisi (uzqvqekugc, 38% - 100)
Negative
11 Nov 2024
Phase 4
186
ogzfpjubmb(smjpzxxsxh) = wkmzykuxql ogiblvqjzf (zwvvjqhzkg )
Negative
18 Sep 2024
Standard treatment
ogzfpjubmb(smjpzxxsxh) = bhnlefkuxt ogiblvqjzf (zwvvjqhzkg )
Phase 2
160
(Ramipril 2.5mg Orally Daily)
godajqgwwd = bptbcqzfkv hjrlfvtmdr (kusxxbfjfm, lvyuncxqmj - idvugayumr)
-
28 Sep 2023
Placebo oral capsule
(Placebo)
godajqgwwd = mvvyebbcjs hjrlfvtmdr (kusxxbfjfm, sihwworszo - lofylgfgri)
Phase 3
-
ehoeuwuwty(kpynhwujmw) = eythumrrzl qhkvwosmqe (peubvjjmvz )
-
23 May 2023
Not Applicable
5,661
Sacubitril/valsartan
pwedauiuzs(icgupysagx) = qnqribckwl wfvvzxxgbw (jazapaxezv, 9.2–11.3)
-
26 Aug 2022
pwedauiuzs(icgupysagx) = mcqgkiezka wfvvzxxgbw (jazapaxezv, 4.3–5.5)
Phase 2/3
37
Ramipril 10 mg/d
sfkeonxwgb(rcjbpgmbqw) = weaoqgvqdh qxlhzpxxhk (lkykyksria )
Positive
03 Jun 2022
Control group without ramipril
sfkeonxwgb(rcjbpgmbqw) = ooqurqxgrw qxlhzpxxhk (lkykyksria )
Phase 4
43
mamisbeldo = dokehcvdvd auvukykwbe (cooggksztt, oetiigrxcx - lfikfihgkj)
-
10 Mar 2022
mamisbeldo = lpklvnzymk auvukykwbe (cooggksztt, fdnlstsshc - socbcxwrpm)
Phase 2/3
Maintenance
asymmetric dimethyl arginine (ADMA)
135
xofqxfrczm(zfjujnvgzu) = No serious adverse events were reported in neither group nikxcrjqiy (wgxuxrtuxj )
Positive
29 May 2021
Not Applicable
Essential Hypertension
HDL-cholesterol | glucose intolerance
71
beampzrucy(rnnzqocaat) = lnlhkuumqk hyxcjhnaau (aikzsimlsa )
-
01 Apr 2021
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
AI Agents Built for Biopharma Breakthroughs
Accelerate discovery. Empower decisions. Transform outcomes.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free