Drug Type Small molecule drug |
Synonyms Angeliq, Angeliq low-low, Estradiol and Drospirenone + [8] |
Target |
Action antagonists, agonists |
Mechanism AR antagonists(Androgen Receptor antagonists), ERs agonists(Estrogen receptors agonists), MR antagonists(Mineralocorticoid receptor antagonists) |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date United States (28 Sep 2005), |
Regulation- |
Molecular FormulaC42H54O5 |
InChIKeyQJUXBIVLOGRZSQ-OQMMLGNJSA-N |
CAS Registry350818-73-4 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | Drospirenone/Estradiol | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Menopausal syndrome | China | 11 Jan 2015 | |
Osteoporosis, Postmenopausal | China | 29 Sep 2009 | |
Vascular Diseases | China | 29 Sep 2009 | |
Vasomotor symptom | United States | 28 Sep 2005 | |
Vulvovaginal atrophy | United States | 28 Sep 2005 | |
Contraception | Canada | - |
Phase 4 | 24 | bmrshqqpxu(mxsmzssxlf) = sttsbyxkpo hbtebtqqqg (hgjileeiza, 3.32) View more | - | 03 May 2013 | |||
Drospirenone (DRSP)+Estradiol (E) (E+DRSP) | bmrshqqpxu(mxsmzssxlf) = ngweiiiqch hbtebtqqqg (hgjileeiza, 3.18) View more | ||||||
Phase 3 | - | 662 | (0.25mg DRSP / 0.5mg E2 (BAY86-4891)) | bxzqibohkw = zjttcyemuk hxkwabdvld (rfnopgkhvv, rmgdmdzhsx - suiigdzhal) View more | - | 28 Jun 2012 | |
0.5mg NETA / 1.0mg E2 (Activella) (0.5mg NETA / 1.0mg E2 (Activella)) | qtbekcftrr = oyntuncgnt zinlzbkscd (xvuqrnoloa, rkllpzqdzf - wgsrbdspkw) View more | ||||||
Phase 3 | 735 | (0.5mg DRSP / 0.5mg E2 (BAY86-4891)) | kcaljyvfit(ibdtsubtnt) = doejcxtiww ckokvcntug (lamfhrnkbw, mqudeylfez - pgnaebfkmh) View more | - | 18 Apr 2012 | ||
(0.25mg DRSP / 0.5mg E2 (BAY86-4891)) | kcaljyvfit(ibdtsubtnt) = dfrawvhfpm ckokvcntug (lamfhrnkbw, aotgslfkgp - xlkoetwehs) View more | ||||||
Phase 2 | 92 | (0.5mg DRSP / 1.0mg E2 (Angeliq, BAY86-4891)) | euyrkhgxss(eklglmnlza) = bphfijxtsy kpnsvuipxz (xmkvuiqhhe, 1.49) View more | - | 20 Jan 2010 | ||
(2.0mg DRSP / 1.0mg E2 (Angeliq, BAY86-4891)) | euyrkhgxss(eklglmnlza) = gmppkesrzq kpnsvuipxz (xmkvuiqhhe, 1.35) View more |