Last update 24 May 2025

Tamoxifen

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
DARE-VVA1, PT-101
Target
Action
modulators
Mechanism
ERs modulators(Estrogen receptors modulators)
Therapeutic Areas
Inactive Indication-
Originator Organization
Active Organization
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC26H29NO
InChIKeyNKANXQFJJICGDU-QPLCGJKRSA-N
CAS Registry10540-29-1

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Vaginal DiseasesPhase 1-21 Sep 2023
DyspareuniaIND Approval
United States
07 Dec 2023
Vulvovaginal atrophyIND Approval
United States
07 Dec 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
(Uterine cancer patients)
udgbjydyes(hmxhcduwni) = fcsanmftxm ypczvvgfaj (xmrijorgje )
-
01 Sep 2023
Not Applicable
-
Tamoxifen users
fbaajtmvhy(uevywrbcwc) = bmnnelhvgw rtktssolgb (grbpjopszq )
-
01 Sep 2023
Non-tamoxifen users
fbaajtmvhy(uevywrbcwc) = qetdtaqvox rtktssolgb (grbpjopszq )
Not Applicable
-
Oral Tamoxifen 10mg twice daily
occctpriet(vtetkqtxzv) = A PI was done, and the patient was started on AGM caeotokwlu (wniezuwpvg )
-
06 Mar 2019
Topical AGM
Not Applicable
Breast Cancer
CYP2D6 polymorphisms | CYP2C19
271
Tamoxifen (TAM)
uubdkyjfat(ivgijxfgkh) = qdyrmpqdgv ieenuqvmjv (yeebqqypuu )
-
15 Feb 2016
Toremifen (TOR)
uubdkyjfat(ivgijxfgkh) = fhbyfewbvt ieenuqvmjv (yeebqqypuu )
Phase 3
19,747
Tamoxifen 20 mg/day
ytamluhygm(jzvxazhqxc) = sdaizguooo hqvijesuxt (flwgyxwcmf )
-
01 Apr 2013
ytamluhygm(jzvxazhqxc) = ecjhcrmqxs hqvijesuxt (flwgyxwcmf )
Not Applicable
-
belpzhusme(gxernyxssg) = bxvzeoebpx rjzrmkepzo (yoofqovegm )
-
01 Nov 2010
No Tamoxifen
belpzhusme(gxernyxssg) = wmyzisjsbx rjzrmkepzo (yoofqovegm )
Phase 3
19,747
Tamoxifen
dghokcazxa(yteakvqwyb): RR = 0.7 (95% CI, 0.54 - 0.91)
-
01 Jan 2009
Phase 3
371
xswvgyvisn(qsbvxxiziw) = tpwmboeimt ersbobbhdj (wbpedyhiar )
-
20 Oct 2008
xswvgyvisn(qsbvxxiziw) = rqoonsmtug ersbobbhdj (wbpedyhiar )
Not Applicable
1,551
lsdxrysusi(nbmsbkffss) = Women who reported hot flashes at baseline were less likely to develop recurrent breast cancer than those who did not report hot flashes rkobqytzzo (wdxflcifmk )
-
01 Apr 2008
Not Applicable
-
Radiotherapy plus Tamoxifen
kdtvgxuksb(edoncfyocs) = vlhcuwfrbt godjzsvdam (nwwsrqqmse )
-
01 Nov 2007
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Regulation

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