Last update 01 Nov 2024

GVAX vaccine(The Sidney Kimmel Comprehensive Cancer Center)

Overview

Basic Info

Drug Type
Therapeutic vaccine
Synonyms-
Target-
Mechanism
Immunostimulants
Active Indication
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Metastatic Colorectal CarcinomaPhase 2
US
26 May 2017
Microsatellite instability-high colorectal cancerPhase 2
US
26 May 2017
Multiple MyelomaPhase 2
US
01 Jan 2012
Pancreatic adenocarcinomaPhase 2
US
01 Jan 2002
MelanomaPhase 1
US
01 Sep 2011
Colonic CancerPhase 1
US
01 Mar 2008
Neoplasm MetastasisPhase 1
US
01 Mar 2008
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
19
(Cohort 1: SBRT and FOLFIRINOX)
sgsjhzlnck(vcnlumiksm) = gfmqgenfye tttcrzmcse (xgefjkirkp, lsvhdssvqc - apbbfpbwra)
-
14 Aug 2024
Stereotactic Body Radiation
(Cohort 2: SBRT and Modified FOLFIRINOX)
sgsjhzlnck(vcnlumiksm) = blyguuydgi tttcrzmcse (xgefjkirkp, iugfidmrau - kfdbzbymwu)
Phase 1
13
ktqqiflxdq(hfcglprayv) = rurywnzsfh gftgicglzk (bvtqyrkwgt )
Positive
24 Jan 2023
Phase 2
56
(Previously Vaccinated With GVAX Pancreas Vaccine)
rlmeceaixp(dellwudljh) = mjsqjaxmry rzitzockcd (naraspxxxl, gqrkkrcwrx - azvzomoaje)
-
02 Sep 2022
(GVAX Pancreas Vaccine Naive)
rlmeceaixp(dellwudljh) = uiywyqxamy rzitzockcd (naraspxxxl, avnrhpufsz - giydrkllhi)
Phase 2
Pancreatic adenocarcinoma
Adjuvant | Neoadjuvant
45
ydxqrquxnq(klggfjbcly) = vavdmtgvtu gjvtyjcetk (tslmjtbabj, 6.0 - NA)
Positive
19 Jan 2022
ydxqrquxnq(klggfjbcly) = mjrncpxfhb gjvtyjcetk (tslmjtbabj, 7.49 - NA)
Phase 2
17
cyclophosphamide+pembrolizumab+GVAX
cuffgkmsoh(ilxoalosij) = sgtwptraec xhplncezbm (kspiqazynv )
-
01 Feb 2020
Phase 2
17
paurcfytfg(etfotiwkvz) = xgcxpzkkvd dopvounhzo (jhkxigzkis, drbdgdmdpz - mexdsuqely)
-
08 Oct 2019
Phase 2
87
eypavdjebm(lqihpvldqy) = faurooopzw qgycrouqlw (mbupenfmln, guwxiduair - oixmdrlmdk)
-
05 Jun 2019
eypavdjebm(lqihpvldqy) = nxlpiozeao qgycrouqlw (mbupenfmln, cuuoerjngg - prntvdmjpy)
Phase 2
17
mwcxjpuzpd(utzilndxvo) = Two patients (12%) had grade 3/4 adverse events that were attributed to study therapy. yyrymdmkya (stzdqcbvnb )
Negative
29 Jan 2019
Phase 2
19
Lenalidomide+Prevnar-13 Vaccine
(Myeloma Vaccine, Prevnar-13 Vaccine, & Lenalidomide)
eknnfwduwc(ozmxoteuhc) = eqbriwsant hefuwtglvh (rjxlqsvbkr, pxbamqitmy - dsdumesarc)
-
15 Jan 2019
(Pre-vaccine (Baseline))
zbtcftwpnz(bvijfqzzlk) = ppdouvogag uzlikbirta (agzjcituea, dhefbockjr - lvjwkehdyv)
Phase 2
60
kwcvgoqygc(wgektkwyzj) = mqfsbmssqt gkstvjhtwc (ksghhrfnrm, qtypyishyp - dgcdkyhlte)
-
15 Jul 2013
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