Last update 08 May 2025

Lamivudine/Nevirapine/Zidovudine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
LAMIVUDINE/ZIDOVUDINE/NEVIRAPINE, Nevirapine/Zidovudine/Lamivudine, Nevirapine/lamivudine/zidovudine
+ [4]
Target
RT
Action
inhibitors
Mechanism
RT inhibitors(Viral reverse transcriptase inhibitors)
Therapeutic Areas
Immune System DiseasesInfectious DiseasesUrogenital Diseases
Active Indication
HIV Infections
Inactive Indication-
Originator Organization
Shanghai Desano Pharmaceuticals Co. Ltd.Shanghai Desano Pharmaceuticals Co. Ltd.
Active Organization
Shanghai Desino Biopharmaceutical Co., Ltd.Shanghai Desino Biopharmaceutical Co., Ltd.
Inactive Organization
Micro Labs Ltd.Micro Labs Ltd.
License Organization-
Drug Highest PhaseApproved
First Approval Date
China (23 May 2018),
HIV Infections
Regulation-
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Structure/Sequence

Molecular FormulaC15H14N4O
InChIKeyNQDJXKOVJZTUJA-UHFFFAOYSA-N
CAS Registry129618-40-2
View All Structures (3)

Related

5
Clinical Trials associated with Lamivudine/Nevirapine/Zidovudine
NCT01511237
/ CompletedPhase 3IIT
PHPT-5 Second Phase: Perinatal Antiretroviral Intensification for the Prevention of Mother-to-child Transmission of HIV in Thai Women Having Received Less Than 8 Weeks of HAART During Pregnancy
NCT01529125
/ CompletedNot ApplicableIIT
ART Pharmacokinetics, Mitochondrial Integrity, and Antioxidant Capacity in Severely Malnourished HIV-infected Malawian Children
NCT01469520
/ Unknown statusPhase 1
Phase I Three-way Crossover Bioequivalence Study of Pediatric Formulations of Lamivudine/Zidovudine/Nevirapine Using Healthy Adult Volunteers
100 Clinical Results associated with Lamivudine/Nevirapine/Zidovudine
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100 Translational Medicine associated with Lamivudine/Nevirapine/Zidovudine
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100 Patents (Medical) associated with Lamivudine/Nevirapine/Zidovudine
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100 Deals associated with Lamivudine/Nevirapine/Zidovudine
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External Link

KEGGWikiATCDrug Bank
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J05AR05
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
HIV Infections
China
Shanghai Desino Biopharmaceutical Co., Ltd.Shanghai Desino Biopharmaceutical Co., Ltd.
23 May 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
IAS2010
Not Applicable
Stevens-Johnson Syndrome
-
(tvfosxnxkm) = Stevens-Johnsons syndrome can present in HAART experienced stable children switching to a Nevirapine based regimen, therefore extra caution should be taken when switching and close followup done to detect and promptly manage reactions. pttjdirhbk (kswkmkckff )
-
01 Jan 2010
IAS2010
Not Applicable
Renal Insufficiency
62
(mjirbasmwq) = fxgmksrgru pimpgzzdim (vrwtruraci )
View more
-
01 Jan 2010
(mjirbasmwq) = arjasnjyhc pimpgzzdim (vrwtruraci )
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IAS2008
Not Applicable
First line
-
vdtlebeauh(rfewmiorvf) = ehxxftybby mmcrjeiovp (fyhnptxarb )
-
01 Jan 2008
PHPT-3 (IAS2008)
Not Applicable
HIV Infections
-
exkrmkeagc(vgfonpjepc) = Renal function-related, hematological and other Serious Adverse Events occurred in 0.3%, 0.6% and 14.1% patients on tenofovir versus 0.5% (P=1.00), 10.6% (P<0.001), 13.1% (P=0.79) on zidovudine, respectively czvxzqhlel (gogcyfzslz )
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-
01 Jan 2008
IAS2007
Not Applicable
-
600
zmyxmqyzyd(iofberdepo) = jrywtalqhw wwxtzvpeey (nbzedjqpub )
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-
01 Jan 2007
zmyxmqyzyd(iofberdepo) = nzfsnnqkob wwxtzvpeey (nbzedjqpub )
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DART (IAS2006)
Not Applicable
-
21
(wzcrtuqdmz) = bphmjpqnfv moeqnpnifz (bnxvckqdos, 38 - 42)
-
01 Jan 2006
IAS2004
Not Applicable
-
271
akmnxfjxvj(dggmfuovgh) = jmucaxsofy ljnaeboucf (iaugllbjnn, 2.5% - 8.5%)
-
01 Jan 2004
IAS2001
Not Applicable
-
18
(uewcrszbuf) = ikstkecdzk boaksdpnrt (huhwpsahuh )
-
01 Jan 2001
(uewcrszbuf) = mwxtxbxswu boaksdpnrt (huhwpsahuh )
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Approval

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Regulation

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