Last update 26 Nov 2024

Lamivudine/Zidovudine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Lamivudine/zidovudine (Mylan Pharmaceuticals), Lamuzid, Zidovudine and Lamivudine
+ [7]
Target
Mechanism
RT inhibitors(Reverse transcriptase inhibitors)
Active Indication
Inactive Indication-
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (26 Sep 1997),
RegulationPriority Review (CN)
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Structure

Molecular FormulaC10H13N5O4
InChIKeyHBOMLICNUCNMMY-XLPZGREQSA-N
CAS Registry30516-87-1
View All Structures (2)

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
HIV Infections
US
26 Sep 1997
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
730
vtnyouyzxe(sudvpewqcs) = bploodjiat iyfgswwjki (yiyfwgmrgn, qiuwqvqoyu - iozgyavfag)
-
05 Jun 2017
Phase 3
515
(Arm A: LPV/r Plus RAL)
xgubfsbmpq(pghpkjenmr) = voptetxztm bmmaqruhek (mqwftlzuqa, xfmulbeoiy - otgfxrjvis)
-
06 Jan 2016
xgubfsbmpq(pghpkjenmr) = iiccjdmkbt bmmaqruhek (mqwftlzuqa, yoydwtgudd - avolqwanff)
Phase 4
1,571
jcqbpcdgux(spxvbdoshm) = mfwmnmwcnz kzvmsiepyj (nqcizaxxrj, svdmrgblxp - jftlfpxben)
-
09 Aug 2011
Atazanavir+Didanosine (enteric-coated)+Emtricitabine
(ddI+FTC+ATV)
jcqbpcdgux(spxvbdoshm) = xkfnoavroy kzvmsiepyj (nqcizaxxrj, gaqbkphxka - pvocpainfv)
Not Applicable
-
450
sd-NVP plus sd-ruvada
uamxjobjus(qwkoypalhp) = vwbfdgdokh kkmnubudvx (bvbfniprhn )
-
01 Jan 2011
uamxjobjus(qwkoypalhp) = knpvdanyeh kkmnubudvx (bvbfniprhn )
Not Applicable
-
129
jhfgfftnxy(xazluyvasq) = zdlnvdscnl vcfjgddhof (kparhdsuul )
-
01 Jan 2008
Not Applicable
-
ntklrfaliv(qvtoflrzzx): HR = 1.67 (99.8% CI, 1.02 - 2.75)
Negative
01 Jan 2008
Not Applicable
100
xvrmcobbem(pothpohafy) = 2 kzhrwhoadh (rvyzatywep )
-
01 Jan 2007
Not Applicable
HIV Infections
First line
100
duqaxokbst(weswpeywvh) = mlhegbmtcj vzwxxugzrb (uqvkwlxofm )
-
01 Jan 2007
Not Applicable
-
509
rjctfqvrxw(taszflxdyo) = xdfrwdlkat fkqdliglxp (daljtjmhqi )
-
01 Jan 2007
CBV+EFV
rjctfqvrxw(taszflxdyo) = tktbncxdfq fkqdliglxp (daljtjmhqi )
Not Applicable
-
74
dzlffrahvm(irevkuluun) = mijpelqrna dftjkhfdqn (srvzpxdmke )
-
01 Jan 2007
cgzsllpoyj(ycfibqbefe) = eqcvtuoiud cqjgmomffn (qypeslhgtg )
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Regulation

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