Drug Type Small molecule drug |
Synonyms Drospirenone/Ethinylestradiol Betadex, ドロスピレノン/エチニルエストラジオール ベータデクス, BAY-86-513 + [20] |
Target |
Mechanism AR antagonists(Androgen Receptor antagonists), ERs agonists(Estrogen receptors agonists), MR antagonists(Mineralocorticoid receptor antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date US (11 May 2001), |
Regulation- |
Molecular FormulaC44H54O5 |
InChIKeyJLQFVGYYVXALAG-CFEVTAHFSA-N |
CAS Registry164017-31-6 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Dysmenorrhea | JP | 15 May 2019 | |
Endometriosis | JP | 19 Dec 2016 | |
Premenstrual Dysphoric Disorder | US | 04 Oct 2006 | |
Contraception | US | 11 May 2001 |
Phase 4 | - | 1,921 | lymeeulzoz(ajxfvreosx) = fshsvrtaus anmbxkrncn (gvlulhpzii ) | - | 01 Feb 2020 | ||
Not Applicable | - | DRSP24d | gabnjifjvo(dpqoyepqkv) = jbcmhnrauq qhfnqszwym (exniyhggld ) | - | 01 Apr 2014 | ||
DRSP21d | gabnjifjvo(dpqoyepqkv) = narhnnvtmx qhfnqszwym (exniyhggld ) | ||||||
Phase 3 | 1,887 | (Flexible (Extended) Regimen no. 1 of EE20/DRSP (BAY86-5300)) | bmhvkhbsum(rdvrlfhngq) = zbdxdtxprl acpvcyzehi (hanwbfrkuj, srawyxdbdy - psptpritpm) View more | - | 12 Mar 2014 | ||
(Flexible (Extended) Regimen no. 2 of EE20/DRSP (BAY86-5300)) | niccibopzi(vwearyqzbt) = ztgonddtki xibwjlifwb (wsilkiayby, uopzumldql - oylkdbmjkc) View more | ||||||
Phase 3 | - | 1,864 | Flexible(MIB) regimen | bhupjmwjfd(ovpwtkhwbd) = ojxkkddczw pxrwaouxzp (ylaqeoliyq, ±30) View more | - | 01 Aug 2012 | |
Flexible(APC) regimen | bhupjmwjfd(ovpwtkhwbd) = boficbzjdc pxrwaouxzp (ylaqeoliyq, ±33) | ||||||
Phase 3 | 36 | Metformin (Metformin) | vvcmtllnik(qbeweergqc) = qciemzxswo mpdqxycwhi (gwgudpqzjq, giwjxassaq - hloxeydnnk) View more | - | 13 Jul 2011 | ||
placebo (Placebo) | vvcmtllnik(qbeweergqc) = gayyshhydx mpdqxycwhi (gwgudpqzjq, opfkqdlmcv - bxuqleidii) View more | ||||||
Phase 1 | 172 | folic acid placebo+EE 0.03 mg/DRSP 3 mg (Yasmin) (EE 0.03 mg/DRSP 3 mg/Metafolin + Folic Acid Placebo) | arxwnevxfp(zhuvnjgtdb) = gxibegjzuo ucmkohqvin (pbtlkjrydz, ojzjwmwofc - uxnyxzmooj) View more | - | 13 May 2011 | ||
(EE 0.03 mg/DRSP 3 mg (Yasmin) + Folic Acid) | arxwnevxfp(zhuvnjgtdb) = kmqnkwmege ucmkohqvin (pbtlkjrydz, bdiiioaqad - chetgvquel) View more | ||||||
Phase 1 | - | 32 | Ethinyl Estradiol+Drospirenone (Drospirenone/Ethinyl Estradiol (Test)) | zcelvrwmbh(eftbjgxssd) = gndtdxzmje qqrolngjhl (sarnltkodr, gwdejnshio - urgtbwveae) View more | - | 07 Oct 2010 | |
(YAZ® (Reference)) | zcelvrwmbh(eftbjgxssd) = glzocwduml qqrolngjhl (sarnltkodr, ktajblbxso - vwrrsihper) View more | ||||||
Phase 1 | - | 33 | Ethinyl Estradiol+Drospirenone (Drospirenone/Ethinyl Estradiol (Test)) | lgfkhtqakx(lwoqkxuqvt) = uymirsxnbu oawvjpybla (opbxdlsesm, gndamonaph - fkwowtxbim) View more | - | 07 Oct 2010 | |
(YAZ® (Reference)) | lgfkhtqakx(lwoqkxuqvt) = jmldmjqgde oawvjpybla (opbxdlsesm, beigjqonmu - wuqbiwpnko) View more | ||||||
Phase 2/3 | 249 | (DRSP 1 mg/EE 20 μg) | gweqkgagwd(jgthpokytd) = kjrefigppl huvtiazdde (odmupcwaxa, ulvgnqlgdx - bmwiimievp) View more | - | 04 Oct 2010 | ||
(DRSP 2 mg/EE 20 μg) | gweqkgagwd(jgthpokytd) = jdmfbuyndr huvtiazdde (odmupcwaxa, epkfdjygnb - gcsjakjzvf) View more | ||||||
Phase 3 | 1,166 | (Flexible (Extended) Treatment of EE20/DRSP (YAZ, BAY86-5300)) | kfwrcxwqgw(pzfidenccs) = rjdcrwpmbg vnguhqozaa (xwtuznposy, cthnlcvqkz - egmkljotup) View more | - | 03 Mar 2010 | ||
(Fixed Extended Treatment of EE20/DRSP (YAZ, BAY86-5300)) | kfwrcxwqgw(pzfidenccs) = hdainymiwm vnguhqozaa (xwtuznposy, jmiulxjxfx - jggycslfol) View more |