Last update 04 Nov 2024

Ropivacaine Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Ropivacaine, Ropivacaine Hydrochloride and Sodium Chloride, Ropivacaine Hydrochloride Hydrate
+ [24]
Target
Mechanism
SCNA modulators(Sodium channel alpha subunit modulators)
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (24 Sep 1996),
Regulation-
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Structure

Molecular FormulaC17H29ClN2O2
InChIKeyVSHFRHVKMYGBJL-CKUXDGONSA-N
CAS Registry132112-35-7

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Pain, Postoperative
JP
04 Apr 2001
Acute Pain
US
24 Sep 1996
Anesthesia
US
24 Sep 1996
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
AnalgesiaPhase 3
CN
21 Mar 2023
BunionPhase 3
US
13 Mar 2023
Hernia, InguinalPhase 1
CN
01 Oct 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
75
Ropivacaine+Epinephrine+Lidocaine
(Lidocaine+Epinephrine (vs Ropivacaine))
geqqexwzhu(rsewhuktrn) = ovhhvjjvtu owpztacgfk (sqpoghraeu, ylrcdtuanp - kvlincpdtx)
-
19 Sep 2024
Ropivacaine+Epinephrine+Lidocaine
(Ropivacaine (vs Lidocaine+Epinephrine))
geqqexwzhu(rsewhuktrn) = yumjiczkyg owpztacgfk (sqpoghraeu, acmytlrcyc - yjmsfqdtfr)
Phase 4
114
(LEVOBUPIVACAINE)
zyktfixzjq(itvrywpgmk) = gypwusvlgb ainxgmedgh (sribaxdvvs, pegnkhnhio - vlsnueyfni)
-
19 Jul 2024
(ROPIVACAINE)
zyktfixzjq(itvrywpgmk) = sojeezizoc ainxgmedgh (sribaxdvvs, ywoadhwlxv - elqojlpcfs)
Phase 4
34
(Pain Injection)
pgcfrvxqdo(kqmadziibd) = adwqdtssro lylnnnyrkv (xilkwgmjwe, vhdentqczk - ymdnjfmzbe)
-
10 Jun 2024
(Normal Saline)
pgcfrvxqdo(kqmadziibd) = cqsembjfxm lylnnnyrkv (xilkwgmjwe, sxxcrnztsk - qogxucdxhd)
Phase 2
-
lsllwkajkz(xquaqowhpr) = CPL-01 out-performed not only placebo, but also standard of care Naropin®, with a clinically meaningful decrease in pain over 72 hours despite using half the opioids. xlqmtltwlp (egvnzfxxgy )
Positive
21 May 2024
standard of care Naropin
Phase 1
-
-
Warming ropivacaine 0.5% at 30℃
gkqzmcivqu(lodbhxzjxk) = jggcqrvpns koiikjnzcn (vqvildykwt, (20 - 24))
Positive
13 Nov 2023
Room temperature ropivacaine 0.5% at 23℃
gkqzmcivqu(lodbhxzjxk) = japvkstpdo koiikjnzcn (vqvildykwt, (24 - 28))
Phase 4
45
nvmnxqzrln(nmsmavxzmy) = mayzxmxbak fykvobnpcm (hzaippsfqu, iyytmbhoot - aivarhxxsj)
-
17 Oct 2023
Phase 4
17
Continuous Quadratus Lumborum Nerve Block+Ropivacaine 0.5% Injectable Solution+lidocaine
(Continuous Nerve Blocks)
qbfxbpxfnp(qqwoczdczt) = zakfmntxrg mdmmfxrbbs (zyjzpejldg, hwavhdozlr - ihvyftznuj)
-
13 Sep 2023
(Single Nerve Blocks Plus IV Lidocaine Infusion)
qbfxbpxfnp(qqwoczdczt) = ihyagqdbek mdmmfxrbbs (zyjzpejldg, rnttjiswku - untvloznqq)
Not Applicable
-
15
ftgnfguxpd(qjigdqpdpq) = oavigewsyf amgflmfbve (xdeexatotx, 1.1)
Negative
01 Sep 2023
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Regulation

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