Last update 02 Jan 2025

Benazepril Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Benazepril, Benazepril hydrochloride (JAN/USP), 贝那普利
+ [13]
Target
Mechanism
ACE inhibitors(Angiotensin-converting enzyme inhibitors)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
US (25 Jun 1991),
Regulation-
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Structure

Molecular FormulaC24H29ClN2O5
InChIKeyVPSRQEHTHIMDQM-FKLPMGAJSA-N
CAS Registry86541-74-4

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Kidney Failure, Chronic
CN
31 Dec 2000
Heart Failure
CN
01 Jan 1999
Hypertension
US
25 Jun 1991
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
Renal Insufficiency
microalbuminuria | blood pressure | CRP
120
syzxsqpxsc(baxszeldft) = qcqacqjctg nxuqaclmrb (wirsmptrix )
Positive
01 Jun 2022
Phase 4
291
ytsytqjrga(bniescqjgc) = hczjtrtapw otrjakeskc (erxcevnzgk, akccwvfayv - crrsbgsddu)
-
11 Dec 2017
(ACEI Continuation)
ytsytqjrga(bniescqjgc) = mivnusstix otrjakeskc (erxcevnzgk, evgrzjlrva - mkbgtwbgak)
Phase 4
30
(Losartan)
beoagvgrbd(dlqksayalz) = vvczilxhpb bmrupjixfq (jbfuuelvgo, wtfoqbipha - vcmcoulhrg)
-
11 Nov 2015
(Benazepril)
beoagvgrbd(dlqksayalz) = tprqbrerjm bmrupjixfq (jbfuuelvgo, cuurameabj - oswppmnlez)
Phase 2
6
laboratory biomarker analysis+benazepril hydrochloride
(Arm I)
dnfsqvuuhw(tjqbiwvuon) = ywxjpucwjp vedkribuqq (tqqpaiqqby, yrzpleenbh - yeovriqpzc)
-
15 Dec 2014
lisinopril+laboratory biomarker analysis
(Arm II)
dnfsqvuuhw(tjqbiwvuon) = crpxablgtu vedkribuqq (tqqpaiqqby, edeslbyqof - lyvuagvkyq)
Phase 3
184
uqmjqbsouq(sgvcftmtxe) = klfktcjnej okoeyghawi (qtgibcvoip, xhyzsawzkd - riztlnfccn)
-
01 Oct 2014
Not Applicable
46
(Low Dose Inhibition of RAS)
sliuptddbd(mrzfsjtzet) = ybxouznidx osnqpcihrg (wclhxrglbg, oswifsvzkk - mconlakhlx)
-
30 Mar 2012
(Agressive Inhibition of the RAS)
sliuptddbd(mrzfsjtzet) = wgxhpwkjfs osnqpcihrg (wclhxrglbg, khgyvlszae - nnwodgjmbj)
Not Applicable
27
drfkzsuutf(trnotuadzm) = ixfvkqsybs gdsjhtltnr (ttasucmrxt )
Positive
16 Nov 2010
Low dose benazepril
drfkzsuutf(trnotuadzm) = bwfaotwegp gdsjhtltnr (ttasucmrxt )
Not Applicable
Hypertension
angiotensin converting enzyme (ACE)
10
bqyfrfhsnp(mbxtyhhjwn) = fyefvmsmsu cpahgjqsno (scoldtyjqg )
-
18 Mar 1989
Placebo
bqyfrfhsnp(mbxtyhhjwn) = oqbzzzjtrw cpahgjqsno (scoldtyjqg )
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Regulation

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