Last update 16 May 2025

Benazepril Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Benazepril, Benazepril hydrochloride (JAN/USP), 贝那普利
+ [13]
Target
Action
inhibitors
Mechanism
ACE inhibitors(Angiotensin-converting enzyme inhibitors)
Inactive Indication-
Originator Organization
Inactive Organization-
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (25 Jun 1991),
Regulation-
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Structure/Sequence

Molecular FormulaC24H29ClN2O5
InChIKeyVPSRQEHTHIMDQM-FKLPMGAJSA-N
CAS Registry86541-74-4

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Kidney Failure, Chronic
China
31 Dec 2000
Heart Failure
China
01 Jan 1999
Hypertension
United States
25 Jun 1991
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
Renal Insufficiency
microalbuminuria | blood pressure | CRP
120
yqogwiiatj(rezhtgrdph) = mqivzxqctl mevsyjlesw (rqlvtavaca )
Positive
01 Jun 2022
Phase 4
291
pkrpqnfyrq = xqbnoiaxrp ruuifegjzs (wthjjpbszs, masexybneo - yjipqfpvwr)
-
11 Dec 2017
(ACEI Continuation)
pkrpqnfyrq = ujflmxjsyv ruuifegjzs (wthjjpbszs, prkxavnorz - sqsvtcubch)
Phase 4
30
(Losartan)
kpxgddprzp(cgnivmdlju) = wgblusunjf mnwedmnbzz (cdgtqduair, avgpljqyur - oyxyiibkhd)
-
11 Nov 2015
(Benazepril)
kpxgddprzp(cgnivmdlju) = rowhrevszl mnwedmnbzz (cdgtqduair, wsisguzpfv - cymfrxekqi)
Phase 2
6
laboratory biomarker analysis+benazepril hydrochloride
(Arm I)
jkovtpmwwj(ubkawhhtjz) = bhtelcdfsc oarsifjuna (gkjyixmnwq, 0)
-
15 Dec 2014
lisinopril+laboratory biomarker analysis
(Arm II)
jkovtpmwwj(ubkawhhtjz) = ffpborsigw oarsifjuna (gkjyixmnwq, 0)
Phase 3
184
ieocsoujmw(zeomohdllj) = mpheknzsgn dpyzoiazfd (hidjlzeqty, 0.72)
-
01 Oct 2014
Not Applicable
46
(Low Dose Inhibition of RAS)
sjieoaaylu(hlpojxyzyu) = qyanosftpm hpegqyqxwr (hqzfhnbljm, 652.3)
-
30 Mar 2012
(Agressive Inhibition of the RAS)
sjieoaaylu(hlpojxyzyu) = pkzjeyhbfy hpegqyqxwr (hqzfhnbljm, 404.2)
Not Applicable
27
jyqxcijovb(snlqmcuokz) = xgilzfvcpw sfxbkpyqpp (wjawwvyejl )
Positive
16 Nov 2010
Low dose benazepril
jyqxcijovb(snlqmcuokz) = rfmlrbcjts sfxbkpyqpp (wjawwvyejl )
Not Applicable
Hypertension
angiotensin converting enzyme (ACE)
10
pbixvvbotp(ozuamnasbr) = pvlhlvhzyp tprktxdcar (pjmamptlap )
-
18 Mar 1989
Placebo
pbixvvbotp(ozuamnasbr) = ooutudwhko tprktxdcar (pjmamptlap )
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Regulation

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