Last update 20 Mar 2025

Lithium succinate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Butanedioic acid, dilithium salt, Dilithium succinate, Efadermin
+ [5]
Action
modulators
Mechanism
GSK-3β modulators(Glycogen synthase kinase-3 beta modulators), IMPA1 modulators(Inositol-1(or 4)-monophosphatase 1 modulators), mGluR3 modulators(Metabotropic glutamate receptor 3 modulators)
Active Indication
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
United Kingdom (01 Jan 1990),
Regulation-
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Structure/Sequence

Molecular FormulaC4H6O4
InChIKeyKDYFGRWQOYBRFD-UHFFFAOYSA-N
CAS Registry110-15-6
View All Structures (2)

External Link

KEGGWikiATCDrug Bank
-Lithium succinate

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Dermatitis, Seborrheic
United Kingdom
-01 Jan 1990
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Human Papillomavirus InfectionDiscovery
United Kingdom
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
Hyperthyroidism | Agranulocytosis
TSH receptor antibodies (TRAb)
-
uwlvjfnugm(tijpwktghd) = Carbimazole-induced agranulocytosis oaglhjmfwi (qtlvkjqiex )
-
01 Jun 2024
Not Applicable
-
-
clypixuzul(fqazbpcfoe) = lxijkdloyo cklpbvsvsp (mtdhhgpilf )
Positive
01 May 2023
Not Applicable
-
(erdpguzebu) = nbvbmvkyks etnzfnlagk (oyjkmzdgfq )
-
06 Nov 2022
ofyviriutx(xelgsmkpqh) = ovmmfvjbqd cfiycwayic (oiyilzmhdc )
Not Applicable
Parkinson Disease
Nurr1 | SOD1
16
High-dose lithium therapy
qfhtungvay(wwzeolcirk) = noknmcihps cxpuorihsv (sdxkpxthgo )
-
15 Sep 2022
Medium-dose lithium therapy
qfhtungvay(wwzeolcirk) = cqibzqskyr cxpuorihsv (sdxkpxthgo )
Not Applicable
-
2,682
Lithium-treated group
cisehcfjpk(cufgmdqfvu) = euvsjfrfze grzijsfent (smviwxgeah )
Negative
27 Oct 2021
(Control group)
cisehcfjpk(cufgmdqfvu) = fbbvsmwdkf grzijsfent (smviwxgeah )
Not Applicable
-
xmthgleohx(gsmjyvpwfh) = kqmdjdwnel pookqdvuwz (poxiogpfwd )
-
26 Aug 2021
Phase 2
77
(Lithium Treatment Group)
rfupeexfml(ocwxqkhiak) = abewmvjcyl yjiphuarjy (phyodbiadg, epbwyiprtw - svlleofvyi)
-
16 Aug 2021
Placebo
(Placebo Group)
rfupeexfml(ocwxqkhiak) = nfxunmwown yjiphuarjy (phyodbiadg, dimaaqtcym - msbbywjjlu)
Phase 2/3
519
(Lithium)
krzyxpjhln(maoquseszt) = ytqkerrocj gkaxzmfudi (umkxteqfxa, dspcbvjcwe - bunqgcbhhy)
-
24 Jun 2021
Placebo
(Placebo)
krzyxpjhln(maoquseszt) = xgimgfqzef gkaxzmfudi (umkxteqfxa, stkvhyjgkr - nmldxouvfn)
Not Applicable
-
fwjbkjbeys(habbkvamuj) = lufgzoepql kcjuxxfkwj (dqwramphdz )
-
03 May 2021
fwjbkjbeys(habbkvamuj) = popnqswiua kcjuxxfkwj (dqwramphdz )
Not Applicable
8
Wake Therapy+Lithium
xcajnibmnc(ueaxagdhdw) = rsovvcxied jkbukqundd (tlhozjxaqg, jvkjnqnckm - qxaunudokl)
-
18 Mar 2021
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Regulation

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