Last update 23 Jan 2025

Acetyladriamycin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Acetyladriamycin, Daunorubicin Citrate, Leukaemomycin C
+ [1]
Target
Mechanism
Top II inhibitors(Topoisomerase II inhibitors), Apoptosis stimulants, RNA synthesis inhibitors
Active Indication
Originator Organization
Active Organization
Drug Highest PhaseApproved
First Approval Date
SE (01 Jan 1993)
RegulationOrphan Drug (EU)
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Structure/Sequence

Molecular FormulaC27H29NO10
InChIKeySTQGQHZAVUOBTE-VGBVRHCVSA-N
CAS Registry20830-81-3

External Link

KEGGWikiATCDrug Bank
D10787-

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Kaposi Sarcoma
IE
-
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Myeloid LeukemiaPhase 1
SE
15 Aug 2018
Acute Myeloid LeukemiaPhase 1
IL
15 Aug 2018
Acute Myeloid LeukemiaPhase 1
GB
15 Aug 2018
Acute Myeloid LeukemiaPhase 1
US
15 Aug 2018
Acute Myeloid LeukemiaPhase 1
BE
15 Aug 2018
Acute Myeloid LeukemiaDiscovery
BE
15 Aug 2018
Acute Myeloid LeukemiaDiscovery
IL
15 Aug 2018
Acute Myeloid LeukemiaDiscovery
SE
15 Aug 2018
Acute Myeloid LeukemiaDiscovery
US
15 Aug 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
Acute Myeloid Leukemia
FLT3/ITD excluded | RUNX1-RUNX1T1 | NPM1 ...
34
pduzpatpqv(lubivoiwyd) = mvddmaiawx rupetpihmy (izcpnwvbnd )
Positive
04 Sep 2024
pduzpatpqv(lubivoiwyd) = mvphqjbrst rupetpihmy (izcpnwvbnd )
Phase 1/2
6
(Cohort II (Higher Dose Pinometostat))
(qijuuntcih) = dfieqmtxmv cmqfwbizjv (ygywkelbzd, qvjxiwdtms - uozdifluss)
-
11 Jun 2024
(Cohort I (Higher and Lowers Dose Pinometostat))
(jihcuqpoio) = dggbwonvgi myfqphkudb (cxbbddgiqu, tlumssmynm - jgnvpawgls)
Phase 2
120
xckxqxpczq(hseqyptdsk) = mgksnplqvp hnczocbasz (ijqewvvoin, zefcrwhpxt - eewstqwikd)
-
10 Sep 2019
Phase 2
17
(yfzgtbuvdx) = pzqamkapvz tsdthnneez (dajlkhizua, uuyootedtk - sntpkvjezm)
-
25 Jan 2016
Phase 2
60
tzktrudqrt(hsgrghlwgo) = oseyevabst emsnwbecda (fjrqnljdis, wggfltuvzj - yirqslhnly)
-
09 Jun 2014
jwhouiuydw(eumguypuzv) = vbygmyphbc dyvsfafhrh (veviyvecuz, jhmidkiwyh - puwccxraxk)
Not Applicable
21
jgyaxrogax(zhkivczjev) = uuyjtzhdxq redklhrhom (lfiqwspyax )
-
01 Jun 2005
jgyaxrogax(zhkivczjev) = tfiiswpkhi redklhrhom (lfiqwspyax )
Not Applicable
76
(tfsoktecpo) = pancytopenia being the most frequent reported effects jfbctrlgfg (duzrccthwp )
-
01 Jan 2004
(Other treatment options)
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Regulation

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