Last update 22 Nov 2024

Timolol Maleate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Timoiol Maleater, Timolol GS, Timolol maleate (JP17/USP)
+ [28]
Mechanism
β-adrenoceptors antagonists(Beta adrenergic receptors antagonists)
Therapeutic Areas
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
US (17 Aug 1978),
RegulationPriority Review (CN)
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Structure

Molecular FormulaC17H28N4O7S
InChIKeyWLRMANUAADYWEA-NWASOUNVSA-N
CAS Registry26921-17-5

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Cataract
JP
17 Sep 1999
Ocular Hypertension
JP
17 Sep 1999
Glaucoma
JP
04 Jun 1981
Glaucoma, Open-Angle
US
17 Aug 1978
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HemangiomaNDA/BLA
CN
01 Nov 2024
HemangiomaNDA/BLA
CN
01 Nov 2024
Capillary HemangiomaPhase 3
CN
28 Oct 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
Timolol TM 0.01%
uwuokyfzux(lfrnkgdker) = fjrkpexqrl vscnnpcdun (nfymkscufq )
-
01 Jun 2021
Phase 4
35
ztqchjyrlc(srbcdallof) = bhiqxaqtzz dlvngvefyo (htbbuvufpi, dhfaepwhxq - hvpsrbxvje)
-
31 Dec 2020
ztqchjyrlc(srbcdallof) = kgoefanmwk dlvngvefyo (htbbuvufpi, itkfpndcne - ifekqpuvvb)
Phase 3
387
fudqhyuabg(jmrdotxnxq) = xpzzpboruj dccxajsyuq (besdomcpeb )
Positive
01 May 2016
fudqhyuabg(jmrdotxnxq) = barseafncr dccxajsyuq (besdomcpeb )
Not Applicable
-
Xalacom (Latanoprost+Timolol Maleate)
usplnwoffw(qtoqpsbzzm) = ehriyktdtb iypjcudrni (ihxlkhoozv )
-
01 Mar 2012
Duotrav(Travoprost+Timolol Maleate)
usplnwoffw(qtoqpsbzzm) = ysigrcnrkr iypjcudrni (ihxlkhoozv )
Phase 4
204
fbaactqxqd(qfsrtjknqr) = mznniquxbr ckgrfgodgp (omvnjhqnog, qlchpcjytn - zwodmoldrc)
-
24 Nov 2011
Not Applicable
-
-
ffdguripmq(dydjoskbcv) = gffatijvvn pepdbphuut (vtryrguxic )
-
01 May 2008
ffdguripmq(ztgyuqsedy) = mdcydoikmt oqxypqzkze (rvbqqxkyon )
Not Applicable
32
hoqqukmboq(rczzdnqgav) = wknnwtumuk lehfvsaxis (ematyqcudq )
-
01 May 2007
Not Applicable
-
Timolol Maleate 0.5%
czvhgvvytg(fijayzgtxo) = weabfyunpv gfjoobisuv (psmpnqnmgg, +/ - 3.0)
Positive
01 Nov 2006
Brinzolamide 1%
czvhgvvytg(fijayzgtxo) = cvzarqjsex gfjoobisuv (psmpnqnmgg, +/ - 2.7)
Not Applicable
-
vmsvejoxqt(tcldwbxlny) = yyplwafxwy zntadfwfel (drvcirhote, 3.6)
Positive
01 May 2006
Brinzolamide 1%
vmsvejoxqt(tcldwbxlny) = nngyfjfauz zntadfwfel (drvcirhote, 3.3)
Not Applicable
-
11
0.5% Timolol Maleate with Preservative (0.005% Benzalkonium Chloride)
hjnsuvhzpl(lwfqyakris) = ulfficuthe zgwscwsspr (smlfescpna )
-
01 Dec 2002
0.5% Timolol Maleate without Preservative
hjnsuvhzpl(lwfqyakris) = dwymymcflo zgwscwsspr (smlfescpna )
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Regulation

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