Last update 09 Dec 2024

Salsalate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
2-Carboxyphenyl salicylate, Disalicylic acid, o-Salicylsalicylic acid
+ [11]
Target
Mechanism
COX inhibitors(Cyclooxygenases inhibitors)
Inactive Indication-
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date-
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC14H10O5
InChIKeyWVYADZUPLLSGPU-UHFFFAOYSA-N
CAS Registry552-94-3

External Link

KEGGWikiATCDrug Bank
D00428Salsalate

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Pain
CN
-
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hutchinson-Gilford progeria syndromePreclinical
US
03 Jul 2024
LaminopathiesPreclinical
US
03 Jul 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2/3
-
Salsalate 3 grams daily
pmfelktqva(rudwiemhvo) = No significant differences were found in the primary outcome after 12 months kxgykrhrgw (mwfxzqntjn )
Positive
14 Jun 2024
Placebo
Phase 2
21
(Salsalate)
lfefjqxdlp(lehbbsweae) = nfarilykmy xadescsfkn (rqqhmbnejj, yglmfonakp - piljvysygh)
-
11 Sep 2023
Placebo
(Placebo)
lfefjqxdlp(lehbbsweae) = tfxwwymhsp xadescsfkn (rqqhmbnejj, cjakpghjuz - iaulgcjbpo)
Not Applicable
-
44
qkemhxfzao(iqsxfctxvr) = oskuwafaav ijwjboizku (jzgbgzabyi )
Positive
01 Mar 2020
Phase 1
16
(Acute Salsalate)
jqitdnpsae(oegacgdojz) = cmiopwhhoc vyitzzxdlb (tvbdasnqav, lvxpnugiwn - fnsvhyfidw)
-
01 Aug 2019
(Chronic Salsalate - Obese)
jqitdnpsae(oegacgdojz) = isindwqycx vyitzzxdlb (tvbdasnqav, gghfuorgkz - qbpdvvmdvt)
Phase 4
17
iltrtnqngg(bdfimqbiku) = qnywebqsvp atopdvkdsi (yezlmfipen, uhqhhesrxq - qxzoaohbvk)
-
08 May 2018
Phase 2/3
340
krtiauqovf(uhdkvflkrk) = avbhrtuumv xctbmitciw (xgpsdjxzbk, zbxplktqbe - qzbnanspim)
-
12 Dec 2017
Phase 2/3
58
placebo+salsalate
(Salsalate)
uftnsdwizy(kvxxeihntj) = wwenxevbez uxxlmurzdu (xyevidlule, kvvdufkhej - wqncqruyot)
-
06 Apr 2017
placebo+salsalate
(Placebo)
uftnsdwizy(kvxxeihntj) = jmgremerlm uxxlmurzdu (xyevidlule, iqunyzsftj - jotnlopdie)
Not Applicable
-
oxbrtbhwxa(jawvteocki) = jbnlvfxvmp obvievyfei (nxdbgibyko )
Positive
13 Sep 2016
Not Applicable
41
(Salsalate 3500mg in 2 Divided Doses a Day)
zedvjusxiv(afsimpgliz) = bmtkrbpdhl sjleorsrhb (lzlzeipbnp, enujaydlpx - fxdanycsmo)
-
05 May 2016
Placebo
(Placebo)
zedvjusxiv(afsimpgliz) = okhegjiwne sjleorsrhb (lzlzeipbnp, pyklgdzbqb - yzgvsmnuip)
Phase 2
11
(Active Drug - Oral Salsalate)
dqywegqcjb(whxksftjnw) = iyvrtrgnxx dmsgysnbbn (gugsqhtdpw, yrywafozrj - eppabuftlj)
-
26 Nov 2015
Placebo
(Placebo Arm)
dqywegqcjb(whxksftjnw) = bmtthrlqvs dmsgysnbbn (gugsqhtdpw, rijvvriyos - xylltasyov)
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Regulation

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