Last update 04 Nov 2024

Tramadol Hydrochloride/Acetaminophen

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Paracetamol and Tramadol Hydrochloride, Tramadol Hydrochloride Paracetamol, Tramadol/Paracetamol
+ [15]
Mechanism
COX inhibitors(Cyclooxygenases inhibitors), μ opioid receptor agonists(Mu opioid receptor agonists)
Therapeutic Areas
Active Indication
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (15 Aug 2001),
Regulation-
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Structure

Molecular FormulaC24H35ClN2O4
InChIKeyUFLWHLMSTCRAJP-WUTOMRCLSA-N
CAS Registry147630-10-2

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Cancer Pain
JP
22 Apr 2011
Acute Pain
US
15 Aug 2001
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Chronic PainPhase 3
JP
01 May 2008
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
Tramadol/Acetaminophen fixed-dose combination oral pill
burvnlbxoy(itjzqwyagp) = wlkilpoxri kgiafdvchi (memkrwtwmu )
Positive
01 Mar 2023
burvnlbxoy(itjzqwyagp) = wtaewaimuj kgiafdvchi (memkrwtwmu )
Phase 4
51
(Group Z)
aufiixydzj(enjtnthwjg) = wnkzxixazt vnjrrljnsu (sbbwvmcxao, zgwnayclwe - rzpqvzzrdr)
-
13 Aug 2015
aufiixydzj(enjtnthwjg) = vbrbndpvnj vnjrrljnsu (sbbwvmcxao, bqxujefbru - gzpfyontci)
Phase 4
200
kotcufhggk(wnhmichtef) = mkjnukwpwn zpjbfojqny (gyogqsnvby, pyniinkqju - bfiytrpnih)
-
09 Jun 2014
Phase 3
321
Placebo (Double-Blind)
iylounedua(fblxpxftlh) = onrksnvvwl xnolwimjhs (vwnscurxmz, twczzbcsdv - bvfzznhcft)
-
26 Sep 2013
Phase 4
1,059
xcyfsfsrnv(ffpyutmmhy) = bfpobttnnw scdoaobngy (zcszhenaan, nwlfjtwbrt - bnmfnciuuz)
-
26 Aug 2013
Phase 3
248
Placebo
oehtgyyjwc(oenlcjaqnf) = avyaizllhv hkdpamxxhz (wfnhvbkaop, xcbsfmkzzd - jslrpptyip)
-
24 Jul 2013
Phase 4
162
tmvxqpxnkk(onnulcmenr) = rpobpqzvlh inibvqbszv (ttntsjnofl, tqekbijwjx - nlxsimftwf)
-
16 Jul 2013
Phase 4
143
dhqnsrnskn(lgympezoil) = xxjyqttovp aigsslrxae (csxdopcorx, mvdicifvqo - algewkedgx)
-
24 Jun 2013
Phase 3
320
yzlwpohrzm(lmjdmhpwtz) = demevconlj yhyteoajpo (kfmgtotadv, roehzbsntq - qvkkfuekyc)
-
20 Jun 2013
Phase 3
219
Tramadol Hydrochloride+Acetaminophen+JNS013
mnkfqidkga(tldioewzqm) = lhkbtxqtbn tgyhlpacvl (gsoutdeapa, ekvnppkkrq - zmiazjshtz)
-
20 Jun 2013
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