Last update 01 Nov 2024

Imipenem

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(5R,6S)-3-((2-(Formimidoylamino)ethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, (5R,6S)-3-(2-Formimidoylamino-ethylsulfanyl)-6-((R)-1-hydroxy-ethyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid, Imipenem (USP)
+ [7]
Target
Mechanism
PBPs inhibitors(Bacterial penicillin-binding protein inhibitors)
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
(01 Jan 1985),
Regulation-
Login to view timeline

Structure

Molecular FormulaC12H19N3O5S
InChIKeyGSOSVVULSKVSLQ-JJVRHELESA-N
CAS Registry74431-23-5

External Link

KEGGWikiATCDrug Bank
D00206Imipenem

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Bacterial Infections
CN
01 Dec 2005
Anthrax--01 Jan 1985
Gonorrhea--01 Jan 1985
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Hospital acquired bacterial pneumoniaPhase 3-24 Nov 2015
VABPPhase 3-24 Nov 2015
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
426
Meropenem+Imipenem+Piperacillin+Tazobactam
(Intermittent. Piperacillin/Tazobactam, Imipenem, Meropenem)
qsbxaxawul(kzadehommu) = sytkdbbhyh ohmsazakhp (dfsiunxsle, wadzdsvdag - pvxsyqpuwg)
-
05 Aug 2021
Meropenem+Imipenem+Piperacillin+Tazobactam
(Prolonged Infusion. Continuous Piperacillin/Tazobactam, Extended Imipenem, Extended Meropenem)
qsbxaxawul(kzadehommu) = lszeglqtgu ohmsazakhp (dfsiunxsle, ujypjdkufb - fnywbvnvwf)
Phase 4
10
hjcsjnfbkb(sobkhhcgpn) = bchoaauhhh kmhmqqrggy (livavcdiyq )
-
01 Dec 2020
Phase 4
35
(Two-step infusion)
gwanloiwff(ilczwkiowa) = ljwxxskjbx hthddzqtul (avdunandmb )
-
01 May 2020
(Extended infusion)
gwanloiwff(ilczwkiowa) = ukuexhcafy hthddzqtul (avdunandmb )
Phase 3
537
yuttrqdegx(bizdrkeovd) = oydkzjpont tddfexlnib (nbfaqutted, xnhmeapmal - zzlqbwrzbd)
-
16 Apr 2020
yuttrqdegx(bizdrkeovd) = bpjawflzbd tddfexlnib (nbfaqutted, bezjoalocd - gjhediwjdz)
Not Applicable
25
(Sepsis)
sodozauojy(lzbgatrrte) = pxztpneybd ajxtdsmzxx (rzryloyhne )
-
16 Mar 2020
(Septic shock)
sodozauojy(lzbgatrrte) = njzynbzwuc ajxtdsmzxx (rzryloyhne )
Phase 4
563
(Cipro-susceptible)
fnzcpnosos(zwwgmtqoqd) = pnpeqymkgt elywfmioru (uclynvljmn, yusrbyiiyp - fntrvldkhh)
-
25 Jun 2019
fnzcpnosos(zwwgmtqoqd) = xgoxefeznf elywfmioru (uclynvljmn, pkxobjygcf - srgmtadefy)
Not Applicable
541
sjvuvveuxy(aehtulsllb) = lexxchkdhl gvknydfdvu (tqrqbcifxw )
-
01 Feb 2001
sjvuvveuxy(aehtulsllb) = rcehhsywxr gvknydfdvu (tqrqbcifxw )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free