ACE inhibitors are a class of drugs that work by relaxing blood vessels, inhibiting the production of the vasoconstrictor substance Angiotensin II. This results in lower blood pressure, reduced cardiac load, and decreased risk of hypertension.
TLRs are innate immune receptors that are responsible, directly or indirectly, for detecting pathogen-associated molecular patterns (PAMPs) and responding to them through the activation of innate and adaptive immune pathways.
Endothelin receptor are G protein-coupled receptors (GPCRs) of the β-group of rhodopsin receptors that bind to endothelin ligands, which are 21 amino acid long peptides derived from longer prepro-endothelin precursors.
DHFR, or dihydrofolate reductase, is an indispensable enzyme required for the survival of most prokaryotic and eukaryotic cells as it is involved in the biosynthesis of essential cellular components.
FcRn, or neonatal Fc receptor, is a crucial protein found in the human body that plays a significant role in the immune system and the pharmacokinetics of therapeutic antibodies.
ERK, also known as Extracellular Signal-Regulated Kinase, is a crucial protein kinase that plays a significant role in various cellular processes within the human body.