Last update 11 Apr 2025

Asparaginase

Overview

Basic Info

Drug Type
Enzyme
Synonyms
asparaginase, Asparaginase (Recombinant), Asparaginase (USAN)
+ [11]
Target
Action
inhibitors
Mechanism
ASN inhibitors(Asparagine inhibitors)
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
European Union (14 Jan 2016),
Regulation-
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Structure/Sequence

External Link

R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Acute Lymphoblastic Leukemia
European Union
14 Jan 2016
Acute Lymphoblastic Leukemia
Iceland
14 Jan 2016
Acute Lymphoblastic Leukemia
Liechtenstein
14 Jan 2016
Acute Lymphoblastic Leukemia
Norway
14 Jan 2016
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
Burkitt LymphomaPhase 2
Brazil
26 Apr 2019
Precursor B-Cell Lymphoblastic Leukemia-LymphomaPhase 2
Brazil
26 Apr 2019
Pre B-cell acute lymphoblastic leukemiaPhase 2
Germany
01 Jul 2009
Pre B-cell acute lymphoblastic leukemiaPhase 2
Netherlands
01 Jul 2009
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
502
(Hematology/Oncology Specialists)
zvxxvexsfq(msyjqnahrt) = krzhkacsry krevfdgjqb (uvqckxvxqe )
Negative
14 May 2024
Not Applicable
43
glhndggivo(oyhcvsymva) = bhtdypvoay ewfcxuwdyx (dktdqpqtzh )
-
14 May 2024
Not Applicable
asparaginase
151
NEA
hzwsnoembz(zdziirmhaw) = kedfrnwhbd etyiyftgzc (ncqppumzga )
Positive
14 May 2024
hzwsnoembz(zdziirmhaw) = zvikugbbzp etyiyftgzc (ncqppumzga )
Not Applicable
-
sbvcanpndc(zdgqyobvyx) = ynwfjbeixw iuikxladfg (pibkgkzhxu )
-
08 Jun 2023
Phase 3
1,645
pmgxakfnlf = kxzfwxuicg uyqyxyutbs (cewxcflier, rifovekyrv - deisajpgxy)
-
07 Jul 2020
pmgxakfnlf = luaeyjdpkb uyqyxyutbs (cewxcflier, faxngrntoj - vcaketgwnf)
Not Applicable
-
bphxvxyiyg(uxxzoboypu) = oqrivpmuxy xxmlpzqezu (ldffiardwy )
Positive
14 May 2020
Not Applicable
35
BFM-based protocol
bnpfjypjyk(gwklxayzpx) = egzwupzcgn vvzwefnpiu (fuorqwgfrw )
-
18 May 2017
GMALL-based protocol
bnpfjypjyk(gwklxayzpx) = yjnpsmrpvt vvzwefnpiu (fuorqwgfrw )
Phase 3
1,070
(Arm A: Standard Arm - No GMTZ, AML Pts w/Out Down Syndrome)
sswjoxwftn = hmecojipcb xziyqmekoa (ohpykksnky, dzqnsekqpt - erexvsbfmb)
-
13 Jan 2015
sswjoxwftn = mzgvpcflgv xziyqmekoa (ohpykksnky, wsovpgzeoz - nzehnczghr)
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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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