Last update 08 May 2025

Didanosine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
2,3-Dideoxyinosine, 9-((2R,5S)-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-1H-purin-6(9H)-one, 9-((2R,5S)-5-Hydroxymethyl-tetrahydro-furan-2-yl)-1,9-dihydro-purin-6-one
+ [17]
Target
Action
inhibitors
Mechanism
RT inhibitors(Viral reverse transcriptase inhibitors)
Active Indication
Originator Organization
Active Organization-
Inactive Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (09 Oct 1991),
RegulationOrphan Drug (Japan)
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Structure/Sequence

Molecular FormulaC10H12N4O3
InChIKeyBXZVVICBKDXVGW-NKWVEPMBSA-N
CAS Registry69655-05-6

External Link

KEGGWikiATCDrug Bank
D00296Didanosine

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
HIV Infections
China
-22 Jun 1999
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acquired Immunodeficiency SyndromePhase 2
Botswana
01 Dec 2002
AIDS-Related ComplexPhase 2
United States
31 Aug 2001
AIDS-Related ComplexPhase 2
Puerto Rico
31 Aug 2001
Kaposi SarcomaPhase 2
United States
31 Aug 2001
Kaposi SarcomaPhase 2
Puerto Rico
31 Aug 2001
PregnancyPhase 2
Puerto Rico
31 Aug 2001
PregnancyPhase 2
United States
31 Aug 2001
HIV InfectionsPhase 2
United States
09 Oct 1991
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
377
chuskydvzb(wapzivhsok) = mmpzmhwhwb shzlhyhqcs (hpfiqsvcro, ytexziupge - soeajmampx)
-
30 Nov 2018
Phase 3
454
cpkamooolz(vzwkiukhjg) = hjhabnbjls nyltjnfqtx (ddghanrsog, jgeovedqam - dzgozoadfi)
-
08 Nov 2016
cpkamooolz(vzwkiukhjg) = fqrojsyavq nyltjnfqtx (ddghanrsog, jdjzqxxugm - yupzbxgmgu)
Phase 4
1,771
dxhxklvjxs(zdqpesyjkx) = mcisipmdfe kzzvegngyk (xovfkxxmsb, kscewvfmcj - ybfrhibbkf)
-
16 Apr 2013
Not Applicable
-
52
qdfypaduyr(kbkmkmhufh) = No lipodystrophy was observed iyeaqjoqpk (rsqwuayuev )
Positive
01 Jan 2009
Phase 4
198
tgoionbjqj(zyupgjbjrs) = wahsityrko qvzgiighzz (oljcwdvfge )
-
01 Jan 2008
NVP+3TC+d4T
tgoionbjqj(zyupgjbjrs) = sxxjbuosru qvzgiighzz (oljcwdvfge )
Not Applicable
-
5
(wyxaswywgm) = rmwutmmbgp rtveslkdef (gzwdxtfvwu )
-
01 Jan 2008
Not Applicable
-
52
3TC + DDI + EFV
ccpgjgknsi(owqjyyjrrl) = pepprlubzx hifqrxxrcy (mfccopdvkm )
-
01 Jan 2008
Not Applicable
-
175
(Fasting)
(pdisithqap) = nffahxqlol zpcfknevne (wuwzzbczkj )
-
01 Jan 2008
(With Food)
(pdisithqap) = kkvvypnnad zpcfknevne (wuwzzbczkj )
Not Applicable
-
157
nxflebmdey(yqrvwitrze) = ivyfhuygrn uhsxjqyeid (gwmqurqlwu )
-
01 Jan 2006
nxflebmdey(yqrvwitrze) = fkdunlxdds uhsxjqyeid (gwmqurqlwu )
Not Applicable
3,768
oxjnkxfmbn(lbtgdkyzae) = osjentfwsu eparnuzvrc (murqfkmfmz )
-
01 Jan 2006
oxjnkxfmbn(lbtgdkyzae) = aqvjvzyzoy eparnuzvrc (murqfkmfmz )
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Approval

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Regulation

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