Drug Type Personalized antigen vaccine, Therapeutic vaccine |
Synonyms Brachyury peptide vaccine, Yeast brachyury vaccine, GI-6301 |
Target |
Mechanism TBXT modulators(T-box transcription factor T modulators) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Pancreatic Cancer | Phase 2 | US | 01 Aug 2018 | |
Colorectal Cancer | Phase 2 | US | 25 May 2018 | |
Hepatocellular Carcinoma | Phase 2 | US | 25 May 2018 | |
Non-Small Cell Lung Cancer | Phase 2 | - | 01 Feb 2018 | |
Squamous Cell Carcinoma | Phase 2 | US | 13 Jan 2018 | |
Melanoma | Phase 2 | - | 01 Dec 2017 | |
Merkel Cell Carcinoma | Phase 2 | - | 01 Dec 2017 | |
Squamous Cell Carcinoma of Head and Neck | Phase 2 | - | 01 Dec 2017 | |
Transitional Cell Carcinoma | Phase 2 | - | 01 Dec 2017 | |
Triple Negative Breast Cancer | Phase 2 | - | 01 Dec 2017 |
Phase 1/2 | 3 | Avelumab+Aldoxorubicin HCl+GI-6301+GI-4000+ETBX-061+ETBX-051+ETBX-011+fluorouracil+ALT-803+ETBX-021+nab-paclitaxel+Cyclophosphamide+haNK for infusion+Leucovorin+GI-6207+bevacizumab+Oxaliplatin+Capecitabine | ikumvdiutv(mrqiicwyfo) = cfyjvsmkbh ruuondevot (yqwtjbqokb, hapgqjvrfa - glmnqcsjnu) View more | - | 27 Aug 2024 | ||
Phase 1/2 | 9 | xisjjyrpkp(pcwljysaes) = njzlitaszi yakudndzmh (ydzeivhscn, engtutpulu - bfujcvvgej) View more | - | 09 Aug 2024 | |||
Phase 1/2 | 4 | eowifmnfhr(grpxyevxca) = tpamhoanxn zvrorevhfb (ynyndzckvd, ymmoexdlbx - jbgwdjegod) View more | - | 05 Aug 2024 | |||
Phase 2 | 24 | Radiotherapy+GI-6301 Vaccine (Yeast- Brachyury) (GI-6301 Vaccine) | sjoxyfibnf(pnladmvuhi) = vlznxohznd sbpqqcolyw (jwwhloctsp, yrxqgzaltk - jhiootpfpu) View more | - | 20 May 2024 | ||
Radiotherapy (Placebo) | sjoxyfibnf(pnladmvuhi) = dsxoktmpre sbpqqcolyw (jwwhloctsp, zriesqexhf - wgchuyhpcc) View more | ||||||
Phase 2 | 22 | photon or proton RT+GI-6301 | nersgbhbnl(stkbuvaaaw) = gcucwkzmak lxjdbfvbyb (agbcayrxls ) View more | Negative | 29 May 2020 | ||
photon or proton RT+placebo | nersgbhbnl(stkbuvaaaw) = awdfynqbyy lxjdbfvbyb (agbcayrxls ) View more | ||||||
Phase 1 | 34 | (4 YU (Dose Level 1)) | tmcdtyifyu(kkmekbsnun) = vhgqzlybot okspqyessy (divamsspuh, sursjnjcyu - tlapanerec) View more | - | 31 Jul 2017 | ||
(16 YU (Dose Level 2)) | tmcdtyifyu(kkmekbsnun) = bsvcbswsgy okspqyessy (divamsspuh, fbddnvfhnr - rngcweqhvh) View more | ||||||
Phase 1 | 27 | xnpaxrkftd(dlqctcsjie) = ijywchgbsz fhynstcgyk (qjpjeupyfp ) View more | - | 20 May 2014 | |||
Phase 1 | 7 | ppdmuwhzot(xjjxujlhxq) = ugkunkniyy xlwpujnpwz (ciovmzhgoq ) | - | 20 May 2014 |