Last update 01 Nov 2025

Recombinant Saccharomyces cerevisiae-CEA(GlobeImmune)

Overview

Basic Info

Drug Type
Recombinant vector vaccine, Therapeutic vaccine
Synonyms
Recombinant Saccharomyces cerevisiae-CEA (610D), GI 6207, GI-6207
Target
CEA
Action
inhibitors
Mechanism
CEA inhibitors(Carcinoembryonic antigen inhibitors)
Therapeutic Areas
NeoplasmsDigestive System DisordersEndocrinology and Metabolic Disease+ [3]
Active Indication-
Inactive Indication
Metastatic Colorectal CarcinomaMetastatic Pancreatic CancerNon-Small Cell Lung Cancer+ [8]
Originator Organization
GlobeImmune, Inc.GlobeImmune, Inc.
Active Organization-
Inactive Organization
ImmunityBio, Inc.ImmunityBio, Inc.GlobeImmune, Inc.GlobeImmune, Inc.NantKwest, Inc.NantKwest, Inc.
License Organization
Celgene Corp.Celgene Corp.GlobeImmune, Inc.GlobeImmune, Inc.
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
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Related

15
Clinical Trials associated with Recombinant Saccharomyces cerevisiae-CEA(GlobeImmune)
NCT03563157
/ TerminatedPhase 1/2
NANT Colorectal Cancer (CRC) Vaccine: A Phase 1b/2 Trial of the NANT CRC Vaccine vs Regorafenib in Subjects With Metastatic CRC Who Have Been Previously Treated With Standard-of-Care Therapy
NCT03554109
/ WithdrawnPhase 2
An Open-Label Randomized Phase 2 Trial Of The NANT NEOADJUVANT Triple-Negative Breast Cancer (TNBC) VACCINE VS Standard-Of-Care For The Neoadjuvant Treatment Of Subjects With TNBC
NCT03563144
/ WithdrawnPhase 2
QUILT-3.088 NANT Pancreatic Cancer Vaccine: Phase II Randomized Trial of the NANT Pancreatic Cancer Vaccine vs. Standard-of-Care as First- Line Treatment for Patients With Metastatic Pancreatic Cancer
100 Clinical Results associated with Recombinant Saccharomyces cerevisiae-CEA(GlobeImmune)
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100 Translational Medicine associated with Recombinant Saccharomyces cerevisiae-CEA(GlobeImmune)
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100 Patents (Medical) associated with Recombinant Saccharomyces cerevisiae-CEA(GlobeImmune)
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100 Deals associated with Recombinant Saccharomyces cerevisiae-CEA(GlobeImmune)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Metastatic Colorectal CarcinomaPhase 2
United States
ImmunityBio, Inc.ImmunityBio, Inc.
28 Sep 2018
Triple Negative Breast CancerPhase 2
United States
ImmunityBio, Inc.ImmunityBio, Inc.
01 Sep 2018
Metastatic Pancreatic CancerPhase 2
United States
ImmunityBio, Inc.ImmunityBio, Inc.
01 Aug 2018
Unresectable Hepatocellular CarcinomaPhase 2
United States
ImmunityBio, Inc.ImmunityBio, Inc.
25 May 2018
Non-Small Cell Lung CancerPhase 2-
ImmunityBio, Inc.ImmunityBio, Inc.
01 Feb 2018
Squamous Cell CarcinomaPhase 2
United States
NantKwest, Inc.NantKwest, Inc.
13 Jan 2018
Squamous Cell Carcinoma of Head and NeckPhase 2-
ImmunityBio, Inc.ImmunityBio, Inc.
01 Dec 2017
Transitional Cell CarcinomaPhase 2-
ImmunityBio, Inc.ImmunityBio, Inc.
01 Dec 2017
Unresectable MelanomaPhase 2-
ImmunityBio, Inc.ImmunityBio, Inc.
01 Dec 2017
Thyroid CancerPhase 2
United States
GlobeImmune, Inc.GlobeImmune, Inc.
26 Apr 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
NCT03563157 (CTgov)
Phase 1/2
Metastatic Colorectal Carcinoma
2
(NANT Colorectal Cancer (CRC) Vaccine)
hcrafmlxnu = ghwovczwbh xepjbscdih (nzxvssntiy, almllzssoc - csxetirfxg)
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-
11 Dec 2024
(Regorafenib)
lvukrnqxvm(rjcgsbrzzf) = dkffnbrdah hdsvmjngaz (apbkzwmugz, apyabiuyyl - udeqztnekv)
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NCT01856920 (QUILT-3.006, CTgov)
Phase 2
Thyroid Cancer, Medullary
35
(Surveillance Subjects)
vpncenmvtm = zrvrnqrxxp syrmlhtjeg (sgozlkmovw, stlgtfawtv - pyelxgodbz)
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-
09 Jul 2024
CEA (610D)+GI-6207
(Vaccine Subjects)
vpncenmvtm = hmgeglzqlp syrmlhtjeg (sgozlkmovw, jhrezijyps - gdlihexdyk)
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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