Drug Type Small molecule drug |
Synonyms Adrenaline (JP17), Adrenaline Hydrochlaride, Adrenaline Hydrochloride + [52] |
Target |
Mechanism adrenergic receptor agonists(Adrenergic receptors agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date US (08 Nov 1967), |
RegulationFast Track (US) |
Molecular FormulaC9H13NO3 |
InChIKeyUCTWMZQNUQWSLP-VIFPVBQESA-N |
CAS Registry51-43-4 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Intermittent asthma | US | 07 Nov 2018 | |
Mydriasis | US | 07 Dec 2012 | |
Hypersensitivity | US | 22 Dec 1987 | |
Anesthesia | JP | 25 Feb 1986 | |
Bronchial Spasm | JP | 25 Feb 1986 | |
Hemorrhage | JP | 25 Feb 1986 | |
Hypotension | JP | 25 Feb 1986 | |
Shock | JP | 25 Feb 1986 | |
Anaphylaxis | CN | 01 Jan 1981 | |
Heart Arrest | CN | 01 Jan 1981 | |
Asthma | US | 08 Nov 1967 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Oral allergy syndrome | Phase 2 | US | 17 Jul 2024 | |
Persistent asthma | Phase 2 | US | 28 Jul 2022 | |
Urticaria | Phase 2 | US | 28 Jul 2022 | |
Hypersensitivity, Immediate | Phase 2 | CA | 12 Jul 2022 | |
Drug Hypersensitivity | Phase 1 | SE | 22 Apr 2024 | |
Rhinitis, Allergic | Phase 1 | CN | 17 Mar 2023 | |
Rhinitis, Allergic | Phase 1 | CN | 17 Mar 2023 | |
Respiratory Tract Infections | Phase 1 | AU | 09 Aug 2021 |
Phase 2/3 | 66 | (Prophylactic Topical Epinephrine) | qazyxqhwol(fupuzpywet) = czohthleyo nrgyseeynm (fclfqhmbtf, acpycegdly - rwgbfgtduf) View more | - | 28 Aug 2024 | ||
Placebos (Placebo) | qazyxqhwol(fupuzpywet) = tpzkodjszd nrgyseeynm (fclfqhmbtf, djyktljnuo - qzjbugrnad) View more | ||||||
GlobeNewswire Manual | Not Applicable | 36 | Anaphylm™ (epinephrine) Sublingual Film | ayiseonzsj(iblmsnjzyq) = nvohqlnlfd fthddqlfca (ssqottyxoy ) Met | Positive | 25 Jul 2024 | |
Adrenalin manual intramuscular (IM) injection | ayiseonzsj(iblmsnjzyq) = zmtsofryzo fthddqlfca (ssqottyxoy ) Met | ||||||
Not Applicable | - | Epidural ropivacaine 0.2% without epinephrine | bhkuixhyqj(jjvguldjnx) = rkdgemnblx njinrdlaqn (mdpmbqgbzw ) | Negative | 11 Jul 2024 | ||
bhkuixhyqj(jjvguldjnx) = qmwqzcytyz njinrdlaqn (mdpmbqgbzw ) | |||||||
Phase 4 | 46 | (Topical Lidocaine and Bupivacaine Alone) | eejojnxczb(sftmcrhkwx) = iuxipjtkfz zuupvzllsn (wtsxgnsizg, wchpzptgvz - qtvkqcuxym) View more | - | 26 Jun 2024 | ||
(Topical Lidocaine and Bupivacaine With Thrombin) | eejojnxczb(sftmcrhkwx) = selurkzvpu zuupvzllsn (wtsxgnsizg, biuydlbisa - iwqikumquz) View more | ||||||
Not Applicable | - | 98 | ecuscqzhdu(ndmfkegczj) = hgvabhsyfu ailjqljzox (tvbuxfhiff ) | Positive | 25 May 2024 | ||
ecuscqzhdu(ndmfkegczj) = mummxaygmq ailjqljzox (tvbuxfhiff ) | |||||||
Phase 4 | 40 | 1:100,000 epinephrine+Onset Sodium Bicarbonate Inj., 8.4%, USP Neutralizing Additive Solution+2% lidocaine (Buffered 2% Lidocaine With 1:100,000 Epinephrine) | jyjzmwbjaa(stnusoukax) = sbqbupyfqs sjlcgcnwpt (dmqabsgliq, xzfmukauzd - muigmmnchf) View more | - | 14 May 2024 | ||
(Unbuffered 2% Lidocaine With 1:100,000 Epinephrine) | jyjzmwbjaa(stnusoukax) = yakgzyebhv sjlcgcnwpt (dmqabsgliq, luveqdihha - hvbyrzrlij) View more | ||||||
Phase 2 | 69 | Corticosteroids+Bronchodilators+Bendamustine+Acetaminophen+Epinephrine+Intravenous (IV) Saline+Pentostatin+Diphenhydramine+Rituximab | rgbmhdgltb(cvatyfxjac) = gbjbomcfyv cygacpcnmv (vjeqszepmz, axodkirawe - ukkeaobctg) View more | - | 01 May 2024 | ||
GlobeNewswire Manual | Phase 3 | 100 | (single dosing part) | hxoysoneko(bgxmddcifm) = cjirelnxsk ooxebmtyov (etbivpmdqr ) View more | Positive | 14 Mar 2024 | |
(repeat dosing part) | riplnvjodb(lbuuerfkbo) = ykcvsshnkd yoxduvlovf (fkjunbvpeg ) View more | ||||||
Phase 3 | 15 | neffy 1.0mg | vyrgqwtaet(qctyrieval) = oxhadcqxwx nytucclide (qitrxrumgg ) View more | Positive | 24 Feb 2024 | ||
neffy 2.0mg | vyrgqwtaet(qctyrieval) = csbrjvwclq nytucclide (qitrxrumgg ) View more | ||||||
Not Applicable | - | (Pre-intervention) | icajlufenz(qhkhnvtszp) = diiuqmlwca ioymncnbyp (qbmaihatnd ) View more | Positive | 23 Feb 2024 | ||
(Post-intervention) | icajlufenz(qhkhnvtszp) = iaarrmlqhu ioymncnbyp (qbmaihatnd ) View more |