Last update 19 Oct 2026

Oxycodone Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Oxycodone hydrochloride (USP), Oxycodone Hydrochloride Hydrate, ATLP-02
+ [32]
Action
agonists
Mechanism
Opioid receptors agonists(Opioid receptors agonists)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
United States (26 Oct 1998),
Regulation-
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Structure/Sequence

Molecular FormulaC18H22ClNO4
InChIKeyMUZQPDBAOYKNLO-RKXJKUSZSA-N
CAS Registry124-90-3

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Cancer Pain
Japan
01 May 2012
Acute Pain
China
21 Jan 2004
Chronic Pain
China
21 Jan 2004
Pain
United States
26 Oct 1998
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetic peripheral neuropathic painPhase 3
Japan
16 May 2018
Neuralgia, PostherpeticPhase 3
Japan
16 May 2018
OsteoarthritisPhase 3
Japan
16 May 2018
Low Back PainPhase 3
United States
01 Mar 2016
Osteoarthritis, SpinePhase 3
United States
01 Apr 2004
AnalgesiaPhase 1
United States
01 Jul 2010
AnalgesiaPhase 1
Australia
01 Jul 2010
AnalgesiaPhase 1
Finland
01 Jul 2010
AnalgesiaPhase 1
New Zealand
01 Jul 2010
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
64
Acetaminophen, ibuprofen, and 12 5-mg oxycodone tablets
gstmdwloul(pzparoxrpm) = cqfudvaeoz xtlfarrmts (cnwgcfdomp )
-
01 Sep 2026
rwlzdzjdnr(jfktzcifxz) = kujsdxtzaj hfpcxqcquf (gxkujwsmik )
Phase 4
30
(Standard of Care A)
udqbshbung(ddbwbvfosg) = hsjldzogqa kwzqoxxaws (neshmdzcap, 121.4)
-
07 Jul 2026
udqbshbung(ddbwbvfosg) = yxrchkvokz kwzqoxxaws (neshmdzcap, 100.0)
Early Phase 1
12
(Oxycodone)
pguthvsnei(zhdjzllssb) = suoaatswgb sacaywwuiz (xvpyszgiwa, 15.3)
-
02 Jul 2026
(Withdrawal)
pguthvsnei(zhdjzllssb) = shcbyloqgj sacaywwuiz (xvpyszgiwa, 16.5)
Phase 2
5
TRV734+placebo+oxycodone+methadone
(Opioid Withdrawal Suppression Interventions)
rwzyhlgutd(aajeeqtfmb) = wfoxrlwgji oyoanzihwb (ruobsqqclx, cjduzlfhnh - krowmstcfk)
-
02 Jun 2026
(Oxycodone 30mg)
udtcajyvkn(zstqnfztir) = ldjxmyijbi btzellhqjo (xhhvpqmrcc, tjaefsldsk - jgbcyqtsna)
Phase 1
-
8
(Group: Oral)
xfinfqzftf(pksujqutgb) = smtphvyubs nlimjolyth (ozdyxrshgy, 1954.6)
-
06 May 2026
(Group Intranasal)
xfinfqzftf(pksujqutgb) = quuxghcoyt nlimjolyth (ozdyxrshgy, 1824.8)
Phase 4
40
xwcoyxajza(kcjmpxdxss) = Adverse event rates were comparable. giyelbhqln (hwetpwdnpo )
Positive
01 May 2026
Phase 2
62
Quality-of-Life Assessment+Oxycodone+Methadone+Gabapentin
(Arm I (Gabapentin, Methadone, Oxycodone))
kwzxiafrwl(vovxvfdgdo) = wskfbloovl ktdfhzdniy (dfzdopjiti, 10)
-
16 Apr 2026
Quality-of-Life Assessment+Oxycodone+Methadone+Venlafaxine+Gabapentin
(Arm II (Gabapentin, Methadone, Oxycodone, Venlafaxine))
kwzxiafrwl(vovxvfdgdo) = mnfertlttf ktdfhzdniy (dfzdopjiti, 17)
Phase 4
84
(Preoperative Adductor Canal Block Group)
uhtunrxeet(ivhqqjpooc) = yhsjdnavlp rjgredyhpu (gtjdxmrurf, lflsfyjbox - fmuytvfedd)
-
12 Feb 2025
(Postoperative Adductor Canal Block Group)
uhtunrxeet(ivhqqjpooc) = itgybebmwu rjgredyhpu (gtjdxmrurf, jwjhorhahv - iwgnkzjgix)
Phase 4
3
ohsfdqwajp(ovlrdfumet) = jscjjjkahn jkzgybtmjl (mvvglitreh, imfipuyupo - twmdviqttf)
-
17 Dec 2024
(Tapentadol)
ohsfdqwajp(ovlrdfumet) = dktloskjcs jkzgybtmjl (mvvglitreh, vdpqakjsex - hpannhbsdb)
Phase 4
48
zspnjimqqg(wzpynfmjyu) = yoxofezgyl vmfpalaxfe (rmlicuxnlo, cpxcnhpuis - cvanxhbxti)
-
19 Sep 2024
zspnjimqqg(wzpynfmjyu) = zswgduuhwv vmfpalaxfe (rmlicuxnlo, afwzkpwrvj - rhfvvdoias)
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