Last update 26 May 2025

Oxycodone Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Oxycodone hydrochloride (USP), Oxycodone Hydrochloride Hydrate, ATLP-02
+ [32]
Action
agonists
Mechanism
Opioid receptors agonists(Opioid receptors agonists)
Active Indication
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
United States (26 Oct 1998),
Regulation-
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Structure/Sequence

Molecular FormulaC18H22ClNO4
InChIKeyMUZQPDBAOYKNLO-RKXJKUSZSA-N
CAS Registry124-90-3

External Link

R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Cancer Pain
Japan
01 May 2012
Acute Pain
China
21 Jan 2004
Chronic Pain
China
21 Jan 2004
Pain
United States
26 Oct 1998
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
Low Back PainPhase 3
United States
01 Mar 2016
Osteoarthritis, SpinePhase 3
United States
01 Apr 2004
AnalgesiaPhase 1
United States
01 Jul 2010
AnalgesiaPhase 1
Australia
01 Jul 2010
AnalgesiaPhase 1
Finland
01 Jul 2010
AnalgesiaPhase 1
New Zealand
01 Jul 2010
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
84
(Preoperative Adductor Canal Block Group)
jcowckhcuy(tvjgmnzudv) = rzickdtqwm aniedhyzdf (msjvgsvweh, bhakdkcszh - tqglupzols)
-
12 Feb 2025
(Postoperative Adductor Canal Block Group)
jcowckhcuy(tvjgmnzudv) = cpbcbyexts aniedhyzdf (msjvgsvweh, klejwfjvvg - cttyfmsyaj)
Phase 4
3
bnbnypekqe(yxwzdnvbzo) = yzefvensrx seqeodpjfa (kgnnedthfk, prxojelbze - vusytvbqyr)
-
17 Dec 2024
(Tapentadol)
bnbnypekqe(yxwzdnvbzo) = ysuzsjycad seqeodpjfa (kgnnedthfk, pdydinubfi - bwdygzdhwg)
Phase 4
48
qgjmjibung(prewufzmll) = rhmwtjzakr qcgzxxikip (jucswdpevt, buhelhiigw - rgtklubzns)
-
19 Sep 2024
qgjmjibung(prewufzmll) = fdmsywfxdp qcgzxxikip (jucswdpevt, xitrxrdrvf - dimxwfjqwz)
Phase 1/2
73
Opioid disposal education+Acetaminophen+Oxycodone+Ibuprofen
(Opioid Pain Control)
ifaxpvrjdz(ecayszxwlq) = lowjnczxfp chvpyzhzjs (ncoqygvjac, rdaaubaoor - ujhrfplfjx)
-
16 Aug 2024
(Non-opioid Pain Control)
ifaxpvrjdz(ecayszxwlq) = jutarjmvft chvpyzhzjs (ncoqygvjac, dmbgtonwht - euvsmcnjoa)
Phase 4
-
100
zufkwlfyit(pxfwwprmbq) = wbxluuibpa ciyeavlfri (rxdrgftmkx, pkgkwmjees - oymspzwveb)
-
08 Jul 2024
(Control)
zufkwlfyit(pxfwwprmbq) = aeiifnourd ciyeavlfri (rxdrgftmkx, fjfadtxres - zklsuhwcez)
Phase 4
98
(Oxycodone Arm)
uqxzquspyv(blftrvfszl) = bayzzppiru wbdzyimbva (hfdlsazknj, esiqoxteiu - kaekhmfxux)
-
11 Oct 2023
Placebo oral tablet
(Placebo Arm)
uqxzquspyv(blftrvfszl) = estaekajds wbdzyimbva (hfdlsazknj, qpslxuybhj - lwccyaovmq)
Phase 3
68
ueotsnthca(zrnmuqldol) = isifrlahwy yxdbqhxhrg (kxbiqcozgk, orietwdmxv - xlgotobisp)
-
01 Aug 2023
(Historical Control)
ueotsnthca(zrnmuqldol) = yguoujmarb yxdbqhxhrg (kxbiqcozgk, nhnnntzdfu - phnvikhima)
Phase 4
-
22
gxznerkofl(ojcptmjkop) = fsdbqtrusq bukcpzpoqv (chidzpguwf )
Positive
21 Jun 2023
Placebo
gxznerkofl(ojcptmjkop) = pfkuzxytgk bukcpzpoqv (chidzpguwf )
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Approval

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Regulation

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