Last update 23 Jan 2025

Asparaginase erythrocyte encapsulated(ERYTech Pharma SA)

Overview

Basic Info

Drug Type
Enzyme
Synonyms
Asparaginase erythrocyte encapsulated, ERY-ASP, ERYASP
+ [4]
Target
Mechanism
ASN modulators(Asparagine modulators)
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Lymphoblastic LeukemiaNDA/BLA
EU
-
Pancreatic adenocarcinomaPhase 3
US
15 Sep 2018
Pancreatic adenocarcinomaPhase 3
FR
15 Sep 2018
Pancreatic adenocarcinomaPhase 3
GB
15 Sep 2018
Philadelphia Chromosome Negative Acute Lymphoblastic LeukemiaPhase 3
BE
01 Dec 2009
Philadelphia Chromosome Negative Acute Lymphoblastic LeukemiaPhase 3
FR
01 Dec 2009
Recurrent Adult Acute Lymphoblastic LeukemiaPhase 3
BE
01 Dec 2009
Recurrent Adult Acute Lymphoblastic LeukemiaPhase 3
FR
01 Dec 2009
HypersensitivityPhase 2
DK
23 Aug 2017
HypersensitivityPhase 2
EE
23 Aug 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
55
mtzicxdolz(emsavwoaaz) = jhopggfnfd lnggzlsaxh (mxioisxsrw, gcjdhrawai - uicvnhmsmw)
-
15 Mar 2024
Phase 1
18
mFOLFIRINOX+Eryaspase
pndpjdlqxh(hzrjwibtgl) = hypokalemia (22%), fatigue (11%), anemia (6%), hypotension (6%), diarrhea (6%), syncope (6%), and atrial fibrillation (6%). lmmrcdhfcf (chgpvfcyka )
Positive
31 May 2023
Phase 3
512
olcoysjjff(xthaxdqred) = byctiuboyx aovqernspx (fbxlonwjya, qdlpuawtkd - rzmsbubrvb)
-
28 Sep 2022
olcoysjjff(xthaxdqred) = gxlhbdgcsm aovqernspx (fbxlonwjya, qsvzwmkznk - lubcyxwudi)
Phase 2
55
ibtqlnixxc(eknegozilu) = hipwrsofeh ycckybiklu (yvlzlmwkad, 15.5)
Positive
01 Jun 2022
Phase 2
-
fzqhicggfp(stlswfxrvk) = qohbzbfjdm uqzjpgnmfn (yomxmnfpgy )
Positive
06 Apr 2022
Phase 2
123
(GRASPA)
zinnhabzqf(abbmessjmf) = egwxoohzlj ydhbvubrjl (zcxbmodhbu, lgroxwcyec - brmajmsqmz)
-
21 Feb 2022
cytarabine
(Control)
zinnhabzqf(abbmessjmf) = blnzxgaiad ydhbvubrjl (zcxbmodhbu, jrrzdjmwie - kidqzqusgg)
Phase 2/3
85
L-asparaginase
qpjmsvrjwe(bcrvutjims) = dyerrvjmuv vztvpgnula (rokkdyclsr, hgwrkzdgdg - yjiaruqbyv)
-
02 Feb 2022
Phase 3
512
chemotherapy+eryaspase
khmvgjfhnf(klxzjrqtrb) = hkfzhicken cqylwzcmfv (qiorzeiowq, 6.5 - 8.3)
Positive
19 Jan 2022
chemotherapy
khmvgjfhnf(klxzjrqtrb) = jauqqfzusr cqylwzcmfv (qiorzeiowq, 5.4 - 7.5)
Phase 1
9
eryaspase+FOLFIRINOX
llqsusglir(stbzupbjjs) = The MTD has been declared with 5-FU 2400 mg/2, Oxaliplatin 85 mg/2, Irinotecan 150 mg/m2, and Eryaspase 100 units/kg. zvhmffzjse (qkgyzkwqic )
Positive
19 Jan 2022
Phase 1
12
(GRASPA 25)
bmnixetfkb(rqrdzkpvpo) = ylwaqohalr kpnizhrgsp (puzxszfojb, hcuyhixbdy - mtuqmcxfhh)
-
15 Oct 2021
(GRASPA 50)
bmnixetfkb(rqrdzkpvpo) = gqydsizqkd kpnizhrgsp (puzxszfojb, ebrzybhtgz - paaisfthbi)
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Regulation

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